Year 2019, Volume 22 , Issue 6, Pages 928 - 934 2019-12-31

Çörek Otu Tohumu Yağının Kimyasal İçeriği ve Biyolojik Aktivite Spektrumu
Chemical Content and Biological Activity Spectrum of Nigella sativa Seed Oil

Yusuf SICAK [1] , Elif Ayşe ERDOĞAN ELİUZ [2]


Bu çalışmada, Muğla (Köyceğiz)'de yetişen Nigella sativa (çörek otu) tohumu yağının kimyasal bileşimi ile yağın antioksidan, antikolinesteraz, antimikrobiyal ve üreaz aktivitesinin araştırılması amaçlanmıştır. Bitkinin yağı, Soxhlet aparatı kullanılarak elde edildi. Yağ bileşimi Gaz Kromatografisi-Kütle Spektrometresi (GC-MS) ile belirlendi. GC-MS sonuçlarından, yağın otuz bir bileşeni tespit edilebildi. Yağın ana bileşenleri palmitik asit (% 10.48), linoleik asit (%8.05), o-siemen (% 7.11), 3,5-dimetil sikloheksanol (% 6.68), timokinon (% 6.44), p-tert-butil katekol (% 6.28) ve 8-metil-1-undesen (% 3.28) olarak belirlendi. Biyolojik aktivite test sonuçları tıbbi özelliği olan çörek otu yağının yeni ilaçların keşfinde ve yeni doğal drog preparatların hazırlanmasında kullanılabilecek umut verici bir aday olduğunu göstermektedir.

In this study, it was aimed to investigate the chemical composition and biological activities including antioxidant, anticholinesterase, antimicrobial and urease activity of Nigella sativa seed oil growing in Muğla (Köyceğiz). The oil of plant was obtained using Soxhlet apparatus. Thirty-one components of the oil were determined by Gas Chromatography-Mass Spectrometry (GC-MS). The major components of oil were detected as palmitic acid (10.48%), linoleic acid (8.05%), o-cyemene (7.11%), 3,5-dimethyl cyclohexanol (6.68%), thymoquinone (6.44%), p-tert-buthyl catechol (6.28%) and 8-methyl-1-undecene (3.28%). The findings obtained from biological activity assays showed that Nigella sativa oil was a promising candidate that can be used in the discovery of new drugs and the preparation of new natural drug preparations.

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Primary Language en
Subjects Biology
Journal Section RESEARCH ARTICLE
Authors

Orcid: 0000-0003-2339-5837
Author: Yusuf SICAK (Primary Author)
Institution: MUGLA SITKI KOCMAN UNIVERSITY, KÖYCEĞİZ VOCATIONAL SCHOOL, DEPARTMENT OF PLANT AND ANIMAL PRODUCTION
Country: Turkey


Orcid: 0000-0003-4317-3000
Author: Elif Ayşe ERDOĞAN ELİUZ
Institution: MERSIN UNIVERSITY, TECHNICAL SCIENCES VOCATIONAL SCHOOL, DEPARTMENT OF FOOD PROCESSING
Country: Turkey


Supporting Institution Muğla Sıtkı Koçman University Research Fund
Project Number Project Number: 17/216
Thanks The authors would like to thank the Muğla Sıtkı Koçman University Research Fund (Project Number: 17/216) for the financial support of the antioxidant and anticholinesterase activities in this research project.
Dates

Publication Date : December 31, 2019

APA SICAK, Y , ERDOĞAN ELİUZ, E . (2019). Chemical Content and Biological Activity Spectrum of Nigella sativa Seed Oil. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi , 22 (6) , 928-934 . DOI: 10.18016/ksutarimdoga.vi.537674