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ANTIHYPERTENSIVE DRUG-INDUCED GİNGİVAL HYPERPLASİA: A CASE REPORT

Year 2021, Volume: 7 Issue: 1, 77 - 84, 01.04.2021

Abstract

Calcium channel blockers used in hypertension patients, immunosuppressants used to prevent organ rejection in transplant patients, and anticonvulsants used in epilepsy patients are the three main groups of drugs known to cause drug-induced gingival overgrowth. Drug-induced gingival overgrowth can be controlled through elimination of local factors, mechanical and chemical plaque control, good oral hygiene, and ending medication or replacing it with another drug. This case reveals the pre-treatment and post-treatment clinical status of a patient who was admitted to our clinic with gingival overgrowth complaint due to the use of amplodipine for a long time due to hypertension. In this case, adequate improvement in the gingival tissue was achieved by surgical procedures conducted on the overgrown gingival tissues and careful plaque control

References

  • 1. Seymour RA, Ellis JS, Thomason JM. Risk Factors for Drug-İnduced Gingival Overgrowth. J Clin Periodontol 2000;27:217-223.
  • 2. Sinha A, Oswal S, Shivamurthy R. Amlodipine İnduced Gingival Overgrowth: A Case Report. Int J Case Rep Images 2014;5:509–512.
  • 3. Hallmon WW, Rossmann JA. The Role of Drugs in the Pathogenesis of Gingival Overgrowth. A Collective Review of Current Concepts. Periodontol 2000 1999;21:176-196.
  • 4. Ramon Y, Behar S, Kishon Y, Engelberg IS. Gingival Hyperplasia Caused by Nifedipine-A Preliminary Report. Int J Cardiol 1984;5:195-206.
  • 5. Seymour RA, Ellis JS, Thomason JM, Monkman S, Idle JR. Amlodipine-İnduced Gingival Overgrowth. J Clin Periodontol 1994;21:281-283.
  • 6. Lombardi T, Fiore-Donno G, Belser U, Di Felice R. Felodipine-İnduced Gingival Hyperplasia: A Clinical and Histologic Study. J Oral Pathol Med 1991;20:89-92.
  • 7. Bowman JM, Levy BA, Grubb RV. Gingival Overgrowth İnduced by Diltiazem. A Case Report. Oral Surg Oral Med Oral Pathol 1988;65:183-185.
  • 8. Brown RS, Sein P, Corio R, Bottomley WK. Nitrendipine-İnduced Gingival Hyperplasia. First Case Report. Oral Surg Oral Med Oral Pathol 1990;70:593-596.
  • 9. Mehta AV, Chidambaram B, O'Riordan AC. Verapamil-İnduced Gingival Hyperplasia in Children. Am Heart J 1992;124:535-536.
  • 10. Livada R, Shiloah J. Calcium Channel Blocker-induced Gingival Enlargement. Journal of Human Hypertension 2014;28:10–14.
  • 11. Ciantar M. Nifedipine-İnduced Gingival Overgrowth: Remission Following Non-surgical Therapy. Dent Update 1996;23:374-377.
  • 12. Thomason JD, Fallaw TL, Carmichael KP, Radlinsky MA, Calvert CA. Gingival Hyperplasia Associated With the Administration of Amlodipine to Dogs With Degenerative Valvular Disease (2004-2008). J Vet Intern Med 2009;23:39-42.
  • 13. Harel-Raviv M, Eckler M, Lalani K, Gornitsky M. Nifedipine İnduced Gingival Hyperplasia: A Comprehensive Review and Analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79:715-722.

ANTIHYPERTENSIVE DRUG-INDUCED GİNGİVAL HYPERPLASİA: A CASE REPORT

Year 2021, Volume: 7 Issue: 1, 77 - 84, 01.04.2021

Abstract

Calcium channel blockers used in hypertension patients, immunosuppressants used to prevent organ rejection in transplant patients, and anticonvulsants used in epilepsy patients are the three main groups of drugs known to cause drug-induced gingival overgrowth. Drug-induced gingival overgrowth can be controlled through elimination of local factors, mechanical and chemical plaque control, good oral hygiene, and ending medication or replacing it with another drug. This case reveals the pre-treatment and post-treatment clinical status of a patient who was admitted to our clinic with gingival overgrowth complaint due to the use of amplodipine for a long time due to hypertension. In this case, adequate improvement in the gingival tissue was achieved by surgical procedures conducted on the overgrown gingival tissues and careful plaque control.

References

  • 1. Seymour RA, Ellis JS, Thomason JM. Risk Factors for Drug-İnduced Gingival Overgrowth. J Clin Periodontol 2000;27:217-223.
  • 2. Sinha A, Oswal S, Shivamurthy R. Amlodipine İnduced Gingival Overgrowth: A Case Report. Int J Case Rep Images 2014;5:509–512.
  • 3. Hallmon WW, Rossmann JA. The Role of Drugs in the Pathogenesis of Gingival Overgrowth. A Collective Review of Current Concepts. Periodontol 2000 1999;21:176-196.
  • 4. Ramon Y, Behar S, Kishon Y, Engelberg IS. Gingival Hyperplasia Caused by Nifedipine-A Preliminary Report. Int J Cardiol 1984;5:195-206.
  • 5. Seymour RA, Ellis JS, Thomason JM, Monkman S, Idle JR. Amlodipine-İnduced Gingival Overgrowth. J Clin Periodontol 1994;21:281-283.
  • 6. Lombardi T, Fiore-Donno G, Belser U, Di Felice R. Felodipine-İnduced Gingival Hyperplasia: A Clinical and Histologic Study. J Oral Pathol Med 1991;20:89-92.
  • 7. Bowman JM, Levy BA, Grubb RV. Gingival Overgrowth İnduced by Diltiazem. A Case Report. Oral Surg Oral Med Oral Pathol 1988;65:183-185.
  • 8. Brown RS, Sein P, Corio R, Bottomley WK. Nitrendipine-İnduced Gingival Hyperplasia. First Case Report. Oral Surg Oral Med Oral Pathol 1990;70:593-596.
  • 9. Mehta AV, Chidambaram B, O'Riordan AC. Verapamil-İnduced Gingival Hyperplasia in Children. Am Heart J 1992;124:535-536.
  • 10. Livada R, Shiloah J. Calcium Channel Blocker-induced Gingival Enlargement. Journal of Human Hypertension 2014;28:10–14.
  • 11. Ciantar M. Nifedipine-İnduced Gingival Overgrowth: Remission Following Non-surgical Therapy. Dent Update 1996;23:374-377.
  • 12. Thomason JD, Fallaw TL, Carmichael KP, Radlinsky MA, Calvert CA. Gingival Hyperplasia Associated With the Administration of Amlodipine to Dogs With Degenerative Valvular Disease (2004-2008). J Vet Intern Med 2009;23:39-42.
  • 13. Harel-Raviv M, Eckler M, Lalani K, Gornitsky M. Nifedipine İnduced Gingival Hyperplasia: A Comprehensive Review and Analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79:715-722.
There are 13 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Kübra Ceran Deveci

Metin Çalışır 0000-0001-6607-6532

Abdulsamet Tanık

Merve Birgealp Erdem

Publication Date April 1, 2021
Submission Date September 11, 2020
Published in Issue Year 2021 Volume: 7 Issue: 1

Cite

Vancouver Ceran Deveci K, Çalışır M, Tanık A, Birgealp Erdem M. ANTIHYPERTENSIVE DRUG-INDUCED GİNGİVAL HYPERPLASİA: A CASE REPORT. Aydin Dental Journal. 2021;7(1):77-84.

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