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Year 2020, Volume: 10 Issue: 2, 142 - 147, 29.06.2020
https://doi.org/10.33808/clinexphealthsci.600151

Abstract

References

  • 1. Iddah MA, Macharia BN, Ng’wena AG et al. Thryroid hormones and hematological indices levels in thyroid disorders patients at Moi teaching and referral hospital, Western Kenya. ISRN endocrinology 2013.
  • 2. Dorgalaleh A, Mahmoodi M, Varmaghani B. Effect of thyroid dysfunctions on blood cell count and red blood cell indice. Iranian journal of pediatric hematology and oncology 2013; 3 (2), 73.
  • 3. Kandir S, Keskin E. Effects of hypothyroidism and hyperthyroidism on hematological parameters in rats. Thyroid 2016; 15, 30.

The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status

Year 2020, Volume: 10 Issue: 2, 142 - 147, 29.06.2020
https://doi.org/10.33808/clinexphealthsci.600151

Abstract

Objective: We aimed to investigate neutrophil lymphocyte ratio (NLR), leukocyte count (WBC), mean platelet volume (MPV) and C-reactive
protein levels (CRP) as inflammatory markers according to thyroid function status in hypo-hyperthyroidism patients.


Methods: Data of patients (n=454, age>18) who applied to the Eskisehir Osmangazi University Hospital between March 2018 and December
2018 were evaluated retrospectively. There were 79 patients in hyperthyroidism group (TSH<0.27 μIU/ml, group I), 297 patients in euthyroid
group (TSH=0.27-4.2 μIU/ml, group II) and 78 patients in hypothyroidism group (TSH>4.2 μIU/ml, group III).


Results: Serum TSH, fT4, fT3, anti-TG and anti-TPO levels were found statistically different between groups (p<0.001) but there were no
significant difference in WBC, NLR and MPV between groups. There was a positive correlation between the NLR and CRP (r=0,295, p<0.01). In
addition, NLR was positively correlated with WBC (r=0,412, p<0.001). Serum CRP levels were statistically higher in group I (3.5 mg/L [1.50-11])
than group II (2.1 mg/L [0.86-5.42]), (p<0.001). Although CRP levels were higher in group III (2.5 mg/L [1.18-5.73]) than group II, there was no
significant difference. CRP showed weak positive correlation with fT4 (r=0,118, p<0.05) and negative correlation with TSH (r=-0,108, p<0.05).


Conclusion: High CRP levels may play an important role in the evaluation of hyperthyroidism in terms of thyroid dysfunction observed in the
present study.

References

  • 1. Iddah MA, Macharia BN, Ng’wena AG et al. Thryroid hormones and hematological indices levels in thyroid disorders patients at Moi teaching and referral hospital, Western Kenya. ISRN endocrinology 2013.
  • 2. Dorgalaleh A, Mahmoodi M, Varmaghani B. Effect of thyroid dysfunctions on blood cell count and red blood cell indice. Iranian journal of pediatric hematology and oncology 2013; 3 (2), 73.
  • 3. Kandir S, Keskin E. Effects of hypothyroidism and hyperthyroidism on hematological parameters in rats. Thyroid 2016; 15, 30.
There are 3 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Fatih Kar 0000-0001-8356-9806

Zeynep Küskü Kiraz This is me 0000-0001-7375-8486

Evin Kocatürk 0000-0003-1728-8613

Sema Uslu 0000-0002-2239-7841

Publication Date June 29, 2020
Submission Date August 1, 2019
Published in Issue Year 2020 Volume: 10 Issue: 2

Cite

APA Kar, F., Kiraz, Z. K., Kocatürk, E., Uslu, S. (2020). The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status. Clinical and Experimental Health Sciences, 10(2), 142-147. https://doi.org/10.33808/clinexphealthsci.600151
AMA Kar F, Kiraz ZK, Kocatürk E, Uslu S. The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status. Clinical and Experimental Health Sciences. June 2020;10(2):142-147. doi:10.33808/clinexphealthsci.600151
Chicago Kar, Fatih, Zeynep Küskü Kiraz, Evin Kocatürk, and Sema Uslu. “The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status”. Clinical and Experimental Health Sciences 10, no. 2 (June 2020): 142-47. https://doi.org/10.33808/clinexphealthsci.600151.
EndNote Kar F, Kiraz ZK, Kocatürk E, Uslu S (June 1, 2020) The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status. Clinical and Experimental Health Sciences 10 2 142–147.
IEEE F. Kar, Z. K. Kiraz, E. Kocatürk, and S. Uslu, “The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status”, Clinical and Experimental Health Sciences, vol. 10, no. 2, pp. 142–147, 2020, doi: 10.33808/clinexphealthsci.600151.
ISNAD Kar, Fatih et al. “The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status”. Clinical and Experimental Health Sciences 10/2 (June 2020), 142-147. https://doi.org/10.33808/clinexphealthsci.600151.
JAMA Kar F, Kiraz ZK, Kocatürk E, Uslu S. The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status. Clinical and Experimental Health Sciences. 2020;10:142–147.
MLA Kar, Fatih et al. “The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status”. Clinical and Experimental Health Sciences, vol. 10, no. 2, 2020, pp. 142-7, doi:10.33808/clinexphealthsci.600151.
Vancouver Kar F, Kiraz ZK, Kocatürk E, Uslu S. The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status. Clinical and Experimental Health Sciences. 2020;10(2):142-7.

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