SOME AROMATIC PLANTS USED IN WOUND TREATMENT IN COMPLEMENTARY MEDICINE AND THEIR USAGE METHODS

Fuat Serkan Kapucuk; Hikmet Dinç

Review

SOME AROMATIC PLANTS USED IN WOUND TREATMENT IN COMPLEMENTARY MEDICINE AND THEIR USAGE METHODS

Year 2021, Volume: 2 Issue: 4, 257 - 264, 03.01.2022

Fuat Serkan Kapucuk Hikmet Dinç

Abstract

Phytotherapy is a term used for treatment with plants. Since ancient times, plants have been used in the treatment. Today, the vast majority of medications used for treatment are herbal in origin. In traditional medicine, plants and herbal products are used extensively in the treatment of wounds and burns. It is known that plants have antibacterial, proliferation stimulating, fibroblast stimulating and antioxidant effects on wound healing. Currently, interest in herbal treatment is growing every day, and herbal methods used in traditional medicine are being studied. Special production areas are created for some plant species used for treatment purposes and their oils are extracted or dried products are prepared for use. In this article, current studies were examined to determine the effects of Aloe vera, Calendula officinalis, Panax ginseng, Achillea millfolium, Hypericum perforatum, Momordica charantia, İnula viscosa, Pinus nigra L., Pinus nigra L., Arnebia densiflora, Centaurium erythraea, Micromeria congesta, Plantago major L. and Nigella sativa L. plants, which are used in wound treatment in traditional folk medicine, on wound healing. It has been observed that these plants have herbal medicine potential that can be used in complementary medicine applications.

Keywords

Phytotherapy, plant, burn, wound treatment

References

1. Anonymous: https://tr.wikipedia.org/wiki/Fitoterapi. 11.06.2021.
2. O’Connor B. B., Calabrese C., Cardeña E., et al. Defining and Describing Complementary and Alternative Medicine. Altern Ther Health Med. 1997;3(2):49-57.
3. Bann, C. Turkey Forest Sector Review, Global Environment Overlays Program, Draft Report, WorldBank, Turkish Agency. Ankara. 1998.
4. Kaya, G. An Investigation of the P&P Model Used in Determining the Future Value of Forest Resources as a Medicinal Plant Reserve, Z.K.Ü. Journal of Bartin Faculty of Forestry. 2006;8(9):23-32.
5. Parsak C. K. Sakman G. ve Çelik Ü. Wound Healing, Wound Care and Complications. Journal of Archive Source Review. 2007;16(2):145-159.
6. Onat D. A. Wound Healing. Basic Clinical Sciences. Saraçoğlu F. (ed), Volume 2, Güneş Bookstore Co. Ltd. Ankara. 1989:635-636.
7. Barbul A. Wound healing. Schwartz’s Principles of Surgery. Mc Graw Hill Eight Edition. 2005;223.
8. Maenthaisong R., Chaiyakunapruk N., Niruntraporn S. and Kongkaew C. The Efficacy of Aloe vera Used for Burn Wound Healing: A Systematic Review. Burns. 2007;33(6):713-718.
9. Yu Z. H., Jin C. and Jianmin H. Effect of Aloe vera Polysaccharides on Immunity and Antioxidant Activities in Oral Ulcer Animal Models. Carbohydrate Polymers. 2009;75(2):307-311.
10. Mahendiran D., Subash G., Selvan D. A., Rehana D., Kumar R.S., and Rahiman A.K. Biosynthesis of Zinc Oxide Nanoparticles Using Plant Extracts of Aloe vera and Hibiscus sabdariffa: Phytochemical, Antibacterial, Antioxidant and Antiproliferative Studies. Bionanoscience. 2017;7:530-545.
11. Durusoy Ç. ve Ulusal B. G. Herbal Therapy in Dermatology-Phytotherapy. Türk Dermatoloji Dergisi. 2007;1:47-50.
12. Budovsky A., Yarmolinsky L. and Shabat S. B. Effect of Medicinal Plants on Wound Healing. Wound Rep. Reg. 2015;23:171-83.
13. Aliabadi A., Yosefi A., Mahjoor A. and Farahmand M. Evaluation of Wound Healing Activity Silymarin (Silybum Marianum) in Streptozotocin Induced Experimental Diabetes in Rats. Journal of Animal and Veterinary Advances. 2011;10(24):3287-3292.
14. Anoja, S. A., Wu, J. A. and Yuan, C., Ginseng Pharmacology. Multiple Constituents and Multiple Actions. Biochemical Pharmacology. 1999;58:1685-1693.
15. Shin H., Jeong H., An H., Hong S., Um J., Shin T., Kwon S., Jee S., Seo B., Shin S., Yang D. and Kim H. The effect of Panax Ginseng on Forced Immobility Time & Immune Function in Mice. Indian J. Med. Res. 2006;124:199-206.
16. Kim W. K., Song S. Y., Oh W. K., Kaewsuwan S., Tran T. L. and Kim W. S. Wound Healing Effect of Ginsenoside Rd From Leaves of Panax Ginseng via Cyclic AMP-Dependent Protein Kinase Pathway. European Journal of Pharmacology. 2013;702:285-293.
17. Lee G. Y., Park K. G., Namgoong S., Han S. K., Jeong S. H. and Dhong E. S. Effects of Panax Ginseng Extract on Human Dermal Fibroblast Proliferation and Collagen Synthesis. International Wound Journal. 2016;13:42-46.
18. Lakshmi T., Geetha R., Roy A. And Kumar A. S. Yarrow (Achillea Millefolium L.) A Herbal Medicinal Plant with Broad Therapeutic Use. A Review. Int. J. Pharm Sci. Rev. Res. 2011;9:136-144.
19. Uyar A., Akyol T., Yaman T. ve Keleş Ö. F. Histopathological and Biochemical Investigation of the Effect of Yarrow (Achillea millefolium) on Wound Healing and Oxidative Stress in Experimentally Created Wound Model in Rats. Van Vet J. 2017;28(3):157-163.
20. Süntar İ. P., Akkol E. K., Yılmazer D., Baykal T., Kırmızıbekmez H., Alper M. and Yeşilada E. Investigation on the In Vivo Wound Healing Potential of Hypericum Perforatum L. Journal of Ethnopharmacology. 2010;127(2):467-477.
21. Altan A., Damlar İ., Aras M. H. ve Alpaslan C. The Effect of St. John's Wound (Hypericum Perforatum) on Wound Healing. Arşiv Kaynak Tarama Dergisi. 2015;24(4):578-591.
22. Gerard J. The Herballe or General History of Plantes. Imprinted by John Norton. London. 1597.
23. Kumar S. R., Ashish J. and Satish N. Momordica Charania Linn.: A Mini Review. International Journal of Biomedical Research. 2011;2(11):579-587.
24. Sarı A. O., Oğuz B., Bilgiç A., Tort N., Güvensen A. ve Şenol S. G. Plants Used as Folk Medicine in Aegean and Southern Marmara Regions. Anadolu Journal of AARI. 2010;20(2):1-21.
25. Prasad V., Jain V., Girish D. and Dorle A. K. Wound Hhealing Property of Momordica Charantia L. Fruit Powder. Journal of Herbal Pharmacotherapy. 2009;6(3-4):105-115.
26. Satar N. Y., Topal A., Yanık K., Oktay A., Batmaz E. and İnan K. Comparison of the Effects of Bitter Melon (Momordica Charantia) and Gotu Kola (Centella Asiática) Extracts on Healing of Open Wounds in Rabbits. Kafkas Univ. Vet. Fak. Derg. 2013;19(Suppl-A):A161-A166.
27. Gökbulut A. Pharmacognostic Studies on Some Inula L. Species Grown in Turkey, (PhD Thesis), Ankara: Ankara University Health Sciences Institute. 2011; S: 1.
28. Danıno O., Gottlıeb E. H. and Grossman S. Antioxidant Activity of 1,3-Dicaffeoylquinic Acid From Inula Viscosa. Food Res. Int. 2009;42:1273-1280.
29. Honda G., Yeşilada E., Tabata M., Sezik E., Fujıta T., Takeda Y., Takaıshı Y. and Tanaka T. Traditional Medicine in Turkey VI. Folk medicine in West Anatolia: Afyon, Kütahya, Denizli, Muğla, Aydın Provinces. J. Ethnopharmacol. 1996;53(2):75-87.
30. Sipponen A., Kuokkanen O., Tiihonen R., Kauppinen H. and Jokinen J. J. Natural Coniferous Resinsalve Used to Treat Complicated Surgical Wounds: Pilot Clinical Trial on Healing and Costs. Int. J. Dermatol. 2012;51(6):726-732.
31. Kaya S. Medicinal Botany and Medicinal Plants. Medisan Medisan Publication Series: 68. Ankara. 2008. SS:69-232.
32. Tumen I., Süntar I., Keleş H. And Akkol E. K. A Therapeutic Approach for Wound Healing by Using Essential Oils of Cupressus and Juniperus Species Growing in Turkey. Evid. Based Complement. Alternat. Med. 2012;728281.
33. Aydın H. Wound and Treatment. Nobel Medical Bookstore. İstanbul. 1990.
34. Davis P. H. Flora of Turkey and the East Aegean Islans. Volume 5, Edinburgh University Press. 1975.
35. Baytop T., Dictionary of Turkish Plant Names. Ankara, Atatürk Culture. Language and History High Institution. (1994).
36. Sezik E., Yesilada E., Tabata M., Honda G., Takaishi Y., Fujita T., Tanak T. and Takeda Y. Traditional Medicine in Turkey. 8. Folk Medicine in East Anatolia; Erzurum, Erzincan, Agri, Kars, Igdir Provinces. Econ. Bot. 1997;51(3):195-211.
37. https://tr.wikipedia.org/wiki/Zeytin 14.06.2021.
38. Kaplan M. Women in the Reproduction Process of Traditional Medicine. Intergenerational Study in Ankara City Example. Ankara: Ankara University Press. Ankara University Rectorate Publications: 2010;257.
39. Demirci S. An Ethnobotanical Research in Andırın (Kahramanmaraş) District. Master Thesis. Istanbul University. Institute of Health Sciences. İstanbul. 2010.
40. Baytop T. Herbal Treatment in Turkey (Past and Present). Additive 2nd Edition, Nobel Medicine Bookstores. İstanbul. 1999. S:243.
41. Zlatković B. K., Bogosavljević S. S., Radivojević A. R. and Pavlović M. A. Traditional Use of the Native Medicinal Plant Resource of Mt. Rtanj (Eastern Serbia): Ethnobotanical Evaluation and Comparison. J. Ethnopharmacol. 2014;151(1):704-713.
42. Polat R. and Satı F. An Ethnobotanical Survey of Medicinal Plants in Edremit Gulf (Balıkesir–Turkey). Journal of Ethnopharmacology. 2012;139:629-641.
43. Yavuz Ü., Temamoğulları F., Yığın A. and Yumuşak N. Investigation of the Effects of Topical Centarium Erythraea in Full-Thickness Skin Wounds in Diabetic Rabbits. Dicle Üniv. Vet. Fak. Derg. 2020;13(2):92-98.
44. Dincer C., Torun M., Tontul I., Topuz A., Şahin-Nadeem H., Göktürk R. S., Tugrul-Ay S. and Özdemir F. Phenolic Composition and Antioxidant Activity of Sideritis Lycia and Sideritis Libanotica Subsp. Linearis: Effects of Cultivation, Year and Storage. J. Appl. Res. Med. Arom. Plant. 2017;5:26-32.
45. Özek T., “Composition of Micromeria Congesta Essential Oil’’ Master Thesis. Anadolu University-Institute of Health Sciences. Eskişehir. 1990.
46. Akan H., Aydoğdu M., Korkut M. M. ve Balos, M. M. An Ethnobotanical Research of the Kalecik Mountain Area (Şanlıurfa, South East Anatolia). Biological Diversity and Conservation. 2013;6:84-90.
47. Svendsen A. B. and Scheffer J. J. C. (Ed.): Essential Oils and Aromatic Plants, Martinus Nijhoff / Dr. W. Junk Publishers. Dordrech. 1985.
48. Yavuz U., Dinç. H., Yığın A., Yumuşak N., Aslan M., Yoldaş A., Özel A. and Mızraklıdağ A. S. Investigation of the Effects of Micromeria Congesta Essential Oil Extract on Wound Healing in Rabbits and Molecular Genetics Applications. Indian Journal of Animal Research. 2020:B-1289.
49. Samuelsen, A. B. The Traditional Uses, Chemical Constituents and Biological Activities of Plantago Major L. A Review. Journal of Ethnopharmacology. 2000;71(1-2):1-21.
50. Caro D. C., Rivera D. E., Ocampo Y., Franco L. A. and Salas R. D., Pharmacological Evaluation of Mentha spicata L. and Plantago major L., Medicinal Plants Used to Treat Anxiety and Insomnia in Colombian Caribbean Coast. Evidence-Based Complementary and Alternative Medicine. 2018;5921514:1-7.
51. Kolak U., Boğa M., Uruşak E. A., and Ulubelen A. 'Constituents of Plantago Major Subsp İntermedia With Antioxidant and Anticholinesterase Capacities'. Turkish Journal of Chemistry. 2011;35:637-645.
52. Yeşil Y. An Ethnobotanical Research in Kürecik (Akçadağ/Malatya) Subdistrict. Master Thesis. Istanbul University Institute of Health Sciences, İstanbul. 2007.
53. Khader M. and Eckl P. M. Thymoquinone: An Emerging Natural Drug With a Wide Range of Medical Applications. Iran J. Basic Med. Sci. 2014;17(12):950-957.
54. Güzelsoy P., Aydın S. and Başaran N. Possible Effects of Thymoquinone, Active Component of Black Cumin (Nigella sativa L.) on Human Health. Journal of Literature Pharmacy Sciences. 2018;7(2):118-135.
55. Darakhshan S., Bidmeshki P. A., Hosseinzadeh C. A. and Sisakhtnezhad S. Thymoquinone and its Therapeutic Potentials. Pharmacol Res. 2015;95-96:138-158.
56. Aslan R. ve Borazan S. Black Recipe: Black Cumin (Nigella Sativa L). Journal of Ayrıntı. 2019;7(74):41-47.

TAMAMLAYICI TIPTA YARA TEDAVİSİNDE KULLANILAN BAZI AROMATİK BİTKİLER VE KULLANIM YÖNTEMLERİ

Year 2021, Volume: 2 Issue: 4, 257 - 264, 03.01.2022

Fuat Serkan Kapucuk Hikmet Dinç

Abstract

Fitoterapi bitkilerle tedavi anlamında kullanılan bir terimdir. Çok eski çağlardan beri bitkiler tedavide kullanılmaktadır. Günümüzde tedavi amacıyla kullanılan ilaçların büyük çoğunluğu bitkisel kaynaklıdır. Geleneksel halk tıbbında yara ve yanıkların tedavisinde bitkiler ve bitkisel ürünler yoğun olarak kullanılmaktadır. Bitkilerin yara iyileşmesi üzerine antibakteriyel, proliferasyonu uyarıcı, fibroblastları uyarıcı ve antioksidan etkilerinin olduğu bilinmektedir. Günümüzde bitkisel tedavilere olan ilgi her geçen gün artmakta ve geçmişte halk tıbbında kullanılan bitkisel yöntemler araştırılmaktadır. Tedavi amacıyla kullanılan bazı bitki türleri için özel üretim alanları oluşturularak yağları, ekstreleri çıkarılarak veya kurutulmuş ürünleri hazırlanarak kullanıma sunulmaktadır. Bu makalede geleneksel halk tıbbında yara tedavisinde kullanılan Aleo vera, Calendula officinalis, Panax ginseng, Achillea millfolium, Hypericum perforatum, Momordica charantia, İnula viscosa, Pinus nigra L., Pinus nigra L., Arnebia densiflora, Centaurium erythraea, Micromeria congesta, Plantago major L. ve Nigella sativa L. bitkilerinin yara üzerine etkilerini tespit edilmesi amacıyla yapılan güncel araştırmalar incelenmiş olup bu bitkilerin tamamlayıcı tıp uygulamalarında kullanılabilecek bitkisel ilaç potansiyeli taşıdığı görülmüştür.

Keywords

Fitoterapi,, bitki, yanık, yara tedavisi

References

1. Anonymous: https://tr.wikipedia.org/wiki/Fitoterapi. 11.06.2021.
2. O’Connor B. B., Calabrese C., Cardeña E., et al. Defining and Describing Complementary and Alternative Medicine. Altern Ther Health Med. 1997;3(2):49-57.
3. Bann, C. Turkey Forest Sector Review, Global Environment Overlays Program, Draft Report, WorldBank, Turkish Agency. Ankara. 1998.
4. Kaya, G. An Investigation of the P&P Model Used in Determining the Future Value of Forest Resources as a Medicinal Plant Reserve, Z.K.Ü. Journal of Bartin Faculty of Forestry. 2006;8(9):23-32.
5. Parsak C. K. Sakman G. ve Çelik Ü. Wound Healing, Wound Care and Complications. Journal of Archive Source Review. 2007;16(2):145-159.
6. Onat D. A. Wound Healing. Basic Clinical Sciences. Saraçoğlu F. (ed), Volume 2, Güneş Bookstore Co. Ltd. Ankara. 1989:635-636.
7. Barbul A. Wound healing. Schwartz’s Principles of Surgery. Mc Graw Hill Eight Edition. 2005;223.
8. Maenthaisong R., Chaiyakunapruk N., Niruntraporn S. and Kongkaew C. The Efficacy of Aloe vera Used for Burn Wound Healing: A Systematic Review. Burns. 2007;33(6):713-718.
9. Yu Z. H., Jin C. and Jianmin H. Effect of Aloe vera Polysaccharides on Immunity and Antioxidant Activities in Oral Ulcer Animal Models. Carbohydrate Polymers. 2009;75(2):307-311.
10. Mahendiran D., Subash G., Selvan D. A., Rehana D., Kumar R.S., and Rahiman A.K. Biosynthesis of Zinc Oxide Nanoparticles Using Plant Extracts of Aloe vera and Hibiscus sabdariffa: Phytochemical, Antibacterial, Antioxidant and Antiproliferative Studies. Bionanoscience. 2017;7:530-545.
11. Durusoy Ç. ve Ulusal B. G. Herbal Therapy in Dermatology-Phytotherapy. Türk Dermatoloji Dergisi. 2007;1:47-50.
12. Budovsky A., Yarmolinsky L. and Shabat S. B. Effect of Medicinal Plants on Wound Healing. Wound Rep. Reg. 2015;23:171-83.
13. Aliabadi A., Yosefi A., Mahjoor A. and Farahmand M. Evaluation of Wound Healing Activity Silymarin (Silybum Marianum) in Streptozotocin Induced Experimental Diabetes in Rats. Journal of Animal and Veterinary Advances. 2011;10(24):3287-3292.
14. Anoja, S. A., Wu, J. A. and Yuan, C., Ginseng Pharmacology. Multiple Constituents and Multiple Actions. Biochemical Pharmacology. 1999;58:1685-1693.
15. Shin H., Jeong H., An H., Hong S., Um J., Shin T., Kwon S., Jee S., Seo B., Shin S., Yang D. and Kim H. The effect of Panax Ginseng on Forced Immobility Time & Immune Function in Mice. Indian J. Med. Res. 2006;124:199-206.
16. Kim W. K., Song S. Y., Oh W. K., Kaewsuwan S., Tran T. L. and Kim W. S. Wound Healing Effect of Ginsenoside Rd From Leaves of Panax Ginseng via Cyclic AMP-Dependent Protein Kinase Pathway. European Journal of Pharmacology. 2013;702:285-293.
17. Lee G. Y., Park K. G., Namgoong S., Han S. K., Jeong S. H. and Dhong E. S. Effects of Panax Ginseng Extract on Human Dermal Fibroblast Proliferation and Collagen Synthesis. International Wound Journal. 2016;13:42-46.
18. Lakshmi T., Geetha R., Roy A. And Kumar A. S. Yarrow (Achillea Millefolium L.) A Herbal Medicinal Plant with Broad Therapeutic Use. A Review. Int. J. Pharm Sci. Rev. Res. 2011;9:136-144.
19. Uyar A., Akyol T., Yaman T. ve Keleş Ö. F. Histopathological and Biochemical Investigation of the Effect of Yarrow (Achillea millefolium) on Wound Healing and Oxidative Stress in Experimentally Created Wound Model in Rats. Van Vet J. 2017;28(3):157-163.
20. Süntar İ. P., Akkol E. K., Yılmazer D., Baykal T., Kırmızıbekmez H., Alper M. and Yeşilada E. Investigation on the In Vivo Wound Healing Potential of Hypericum Perforatum L. Journal of Ethnopharmacology. 2010;127(2):467-477.
21. Altan A., Damlar İ., Aras M. H. ve Alpaslan C. The Effect of St. John's Wound (Hypericum Perforatum) on Wound Healing. Arşiv Kaynak Tarama Dergisi. 2015;24(4):578-591.
22. Gerard J. The Herballe or General History of Plantes. Imprinted by John Norton. London. 1597.
23. Kumar S. R., Ashish J. and Satish N. Momordica Charania Linn.: A Mini Review. International Journal of Biomedical Research. 2011;2(11):579-587.
24. Sarı A. O., Oğuz B., Bilgiç A., Tort N., Güvensen A. ve Şenol S. G. Plants Used as Folk Medicine in Aegean and Southern Marmara Regions. Anadolu Journal of AARI. 2010;20(2):1-21.
25. Prasad V., Jain V., Girish D. and Dorle A. K. Wound Hhealing Property of Momordica Charantia L. Fruit Powder. Journal of Herbal Pharmacotherapy. 2009;6(3-4):105-115.
26. Satar N. Y., Topal A., Yanık K., Oktay A., Batmaz E. and İnan K. Comparison of the Effects of Bitter Melon (Momordica Charantia) and Gotu Kola (Centella Asiática) Extracts on Healing of Open Wounds in Rabbits. Kafkas Univ. Vet. Fak. Derg. 2013;19(Suppl-A):A161-A166.
27. Gökbulut A. Pharmacognostic Studies on Some Inula L. Species Grown in Turkey, (PhD Thesis), Ankara: Ankara University Health Sciences Institute. 2011; S: 1.
28. Danıno O., Gottlıeb E. H. and Grossman S. Antioxidant Activity of 1,3-Dicaffeoylquinic Acid From Inula Viscosa. Food Res. Int. 2009;42:1273-1280.
29. Honda G., Yeşilada E., Tabata M., Sezik E., Fujıta T., Takeda Y., Takaıshı Y. and Tanaka T. Traditional Medicine in Turkey VI. Folk medicine in West Anatolia: Afyon, Kütahya, Denizli, Muğla, Aydın Provinces. J. Ethnopharmacol. 1996;53(2):75-87.
30. Sipponen A., Kuokkanen O., Tiihonen R., Kauppinen H. and Jokinen J. J. Natural Coniferous Resinsalve Used to Treat Complicated Surgical Wounds: Pilot Clinical Trial on Healing and Costs. Int. J. Dermatol. 2012;51(6):726-732.
31. Kaya S. Medicinal Botany and Medicinal Plants. Medisan Medisan Publication Series: 68. Ankara. 2008. SS:69-232.
32. Tumen I., Süntar I., Keleş H. And Akkol E. K. A Therapeutic Approach for Wound Healing by Using Essential Oils of Cupressus and Juniperus Species Growing in Turkey. Evid. Based Complement. Alternat. Med. 2012;728281.
33. Aydın H. Wound and Treatment. Nobel Medical Bookstore. İstanbul. 1990.
34. Davis P. H. Flora of Turkey and the East Aegean Islans. Volume 5, Edinburgh University Press. 1975.
35. Baytop T., Dictionary of Turkish Plant Names. Ankara, Atatürk Culture. Language and History High Institution. (1994).
36. Sezik E., Yesilada E., Tabata M., Honda G., Takaishi Y., Fujita T., Tanak T. and Takeda Y. Traditional Medicine in Turkey. 8. Folk Medicine in East Anatolia; Erzurum, Erzincan, Agri, Kars, Igdir Provinces. Econ. Bot. 1997;51(3):195-211.
37. https://tr.wikipedia.org/wiki/Zeytin 14.06.2021.
38. Kaplan M. Women in the Reproduction Process of Traditional Medicine. Intergenerational Study in Ankara City Example. Ankara: Ankara University Press. Ankara University Rectorate Publications: 2010;257.
39. Demirci S. An Ethnobotanical Research in Andırın (Kahramanmaraş) District. Master Thesis. Istanbul University. Institute of Health Sciences. İstanbul. 2010.
40. Baytop T. Herbal Treatment in Turkey (Past and Present). Additive 2nd Edition, Nobel Medicine Bookstores. İstanbul. 1999. S:243.
41. Zlatković B. K., Bogosavljević S. S., Radivojević A. R. and Pavlović M. A. Traditional Use of the Native Medicinal Plant Resource of Mt. Rtanj (Eastern Serbia): Ethnobotanical Evaluation and Comparison. J. Ethnopharmacol. 2014;151(1):704-713.
42. Polat R. and Satı F. An Ethnobotanical Survey of Medicinal Plants in Edremit Gulf (Balıkesir–Turkey). Journal of Ethnopharmacology. 2012;139:629-641.
43. Yavuz Ü., Temamoğulları F., Yığın A. and Yumuşak N. Investigation of the Effects of Topical Centarium Erythraea in Full-Thickness Skin Wounds in Diabetic Rabbits. Dicle Üniv. Vet. Fak. Derg. 2020;13(2):92-98.
44. Dincer C., Torun M., Tontul I., Topuz A., Şahin-Nadeem H., Göktürk R. S., Tugrul-Ay S. and Özdemir F. Phenolic Composition and Antioxidant Activity of Sideritis Lycia and Sideritis Libanotica Subsp. Linearis: Effects of Cultivation, Year and Storage. J. Appl. Res. Med. Arom. Plant. 2017;5:26-32.
45. Özek T., “Composition of Micromeria Congesta Essential Oil’’ Master Thesis. Anadolu University-Institute of Health Sciences. Eskişehir. 1990.
46. Akan H., Aydoğdu M., Korkut M. M. ve Balos, M. M. An Ethnobotanical Research of the Kalecik Mountain Area (Şanlıurfa, South East Anatolia). Biological Diversity and Conservation. 2013;6:84-90.
47. Svendsen A. B. and Scheffer J. J. C. (Ed.): Essential Oils and Aromatic Plants, Martinus Nijhoff / Dr. W. Junk Publishers. Dordrech. 1985.
48. Yavuz U., Dinç. H., Yığın A., Yumuşak N., Aslan M., Yoldaş A., Özel A. and Mızraklıdağ A. S. Investigation of the Effects of Micromeria Congesta Essential Oil Extract on Wound Healing in Rabbits and Molecular Genetics Applications. Indian Journal of Animal Research. 2020:B-1289.
49. Samuelsen, A. B. The Traditional Uses, Chemical Constituents and Biological Activities of Plantago Major L. A Review. Journal of Ethnopharmacology. 2000;71(1-2):1-21.
50. Caro D. C., Rivera D. E., Ocampo Y., Franco L. A. and Salas R. D., Pharmacological Evaluation of Mentha spicata L. and Plantago major L., Medicinal Plants Used to Treat Anxiety and Insomnia in Colombian Caribbean Coast. Evidence-Based Complementary and Alternative Medicine. 2018;5921514:1-7.
51. Kolak U., Boğa M., Uruşak E. A., and Ulubelen A. 'Constituents of Plantago Major Subsp İntermedia With Antioxidant and Anticholinesterase Capacities'. Turkish Journal of Chemistry. 2011;35:637-645.
52. Yeşil Y. An Ethnobotanical Research in Kürecik (Akçadağ/Malatya) Subdistrict. Master Thesis. Istanbul University Institute of Health Sciences, İstanbul. 2007.
53. Khader M. and Eckl P. M. Thymoquinone: An Emerging Natural Drug With a Wide Range of Medical Applications. Iran J. Basic Med. Sci. 2014;17(12):950-957.
54. Güzelsoy P., Aydın S. and Başaran N. Possible Effects of Thymoquinone, Active Component of Black Cumin (Nigella sativa L.) on Human Health. Journal of Literature Pharmacy Sciences. 2018;7(2):118-135.
55. Darakhshan S., Bidmeshki P. A., Hosseinzadeh C. A. and Sisakhtnezhad S. Thymoquinone and its Therapeutic Potentials. Pharmacol Res. 2015;95-96:138-158.
56. Aslan R. ve Borazan S. Black Recipe: Black Cumin (Nigella Sativa L). Journal of Ayrıntı. 2019;7(74):41-47.

There are 56 citations in total.

Details

Primary Language	English
Subjects	Clinical Sciences
Journal Section	Review
Authors	Fuat Serkan Kapucuk 0000-0001-9037-0125 Hikmet Dinç
Early Pub Date	December 29, 2021
Publication Date	January 3, 2022
Published in Issue	Year 2021 Volume: 2 Issue: 4

Cite

Vancouver	Kapucuk FS, Dinç H. SOME AROMATIC PLANTS USED IN WOUND TREATMENT IN COMPLEMENTARY MEDICINE AND THEIR USAGE METHODS. Exp Appl Med Sci. 2022;2(4):257-64.

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