Case Report
Year 2020,
Volume: 3 Issue: 3, 139 - 142, 31.12.2020
Abstract
Akut pankreatit; pankreas bezinin inflamasyonu olup, hayatı tehdit edebilen ölümcül bir durumdur. Bir çok olguda kronik alkol kullanımı ve safra yolu hastalıkları etyolojiden sorumlu olsa da nadiren hipertrigliseridemiye bağlıda akut pankreatit gelişebilir. Trigliserit düzeyleri arttıkça pankreatit gelişme riski artar ve 1000 mg/dl’yi geen düzeylerde hastaların yaklaşık beşte birinde akut pankreatit geliştiği bildirilmiştir. Hipertrigliseridemi nedeniyle meydana gelen pankreatit tedavisinde oral alım kısıtlanlanması, yağdan fakir beslenme, insulin infüzyonu, heparin, lipid düşürücü ilaçlar, nadirende plazmaferez kullanılabilir. Bu yazımızda daha önceden hiç lipid düşürücü ilaç tedavisi almamış ve 3 defa akut pankreatit gelişmiş bir hastayı sunduk. Akut pankreatit etyolojisinde nadiren de olsa yüksek trigliserit düzeyleri sorumlu olabilir. Bu nedenle akut pankreatit gelişen tüm olgular lipid parametreleri açısından incelenmelidir.
References
- 1. Karne S, Gorelick FS. Etiopathogenesis of acute pancreatitis. Surg Clin North Am. 1999;79:699-710.
- 2. Testoni PA. Acute recurrent pancreatitis: Etiopathogenesis, diagnosis and treatment. World J Gastroenterol. 2014;20:16891-16901.
- 3. Zhang XL, Li F, Zhen YM, Li A, Fang Y. Clinical Study of 224 Patients with Hypertriglyceridemia Pancreatitis. Chin Med J (Engl). 2015;128:2045-2049.
- 4. Valdivielso P, Ramírez-Bueno A, Ewald N. Current knowledge of hypertriglyceridemic pancreatitis. Eur J Intern Med. 2014;25:689-694.
- 5. Kimura W, Secknus R, Fischbach W, Mössner J. Role of phospholipase A2 in pancreatic acinar cell damage and possibilities of inhibition: studies with isolated rat pancreatic acini. Pancreas. 1993;8(1):70-79.
- 6. Thompson GR. Primary hyperlipidaemia. Br Med Bull. 1990;46:986-1004.
- 7. Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62:102-111.
- 8. Fredrickson DS. An international classification of hyperlipidemias and hyperlipoproteinemias. Ann Intern Med. 1971;75:471-472.
- 9. Verma N. Introduction to hyperlipidemia and its treatment: a review. Int J Pharm Res. 2016;9:6-14
- 10. Hegele RA, Ginsberg HN, Chapman MJ, et al. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol. 2014;2:655-666.
- 11. Zhang J, Zhu S, Tan D, Ma A, Yang Y, Xu J. A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis. Saudi J Gastroenterol. 2019;25:14-19.
- 12. Zhao XL, Zhu SF, Xue GJ, et al. Early oral refeeding based on hunger in moderate and severe acute pancreatitis: a prospective controlled, randomized clinical trial. Nutrition. 2015;31:171-175.
- 13. Huang W, de la Iglesia-García D, Baston-Rey I, et al. Exocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis. Dig Dis Sci. 2019;64:1985-2005.
Year 2020,
Volume: 3 Issue: 3, 139 - 142, 31.12.2020
Abstract
References
- 1. Karne S, Gorelick FS. Etiopathogenesis of acute pancreatitis. Surg Clin North Am. 1999;79:699-710.
- 2. Testoni PA. Acute recurrent pancreatitis: Etiopathogenesis, diagnosis and treatment. World J Gastroenterol. 2014;20:16891-16901.
- 3. Zhang XL, Li F, Zhen YM, Li A, Fang Y. Clinical Study of 224 Patients with Hypertriglyceridemia Pancreatitis. Chin Med J (Engl). 2015;128:2045-2049.
- 4. Valdivielso P, Ramírez-Bueno A, Ewald N. Current knowledge of hypertriglyceridemic pancreatitis. Eur J Intern Med. 2014;25:689-694.
- 5. Kimura W, Secknus R, Fischbach W, Mössner J. Role of phospholipase A2 in pancreatic acinar cell damage and possibilities of inhibition: studies with isolated rat pancreatic acini. Pancreas. 1993;8(1):70-79.
- 6. Thompson GR. Primary hyperlipidaemia. Br Med Bull. 1990;46:986-1004.
- 7. Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62:102-111.
- 8. Fredrickson DS. An international classification of hyperlipidemias and hyperlipoproteinemias. Ann Intern Med. 1971;75:471-472.
- 9. Verma N. Introduction to hyperlipidemia and its treatment: a review. Int J Pharm Res. 2016;9:6-14
- 10. Hegele RA, Ginsberg HN, Chapman MJ, et al. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol. 2014;2:655-666.
- 11. Zhang J, Zhu S, Tan D, Ma A, Yang Y, Xu J. A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis. Saudi J Gastroenterol. 2019;25:14-19.
- 12. Zhao XL, Zhu SF, Xue GJ, et al. Early oral refeeding based on hunger in moderate and severe acute pancreatitis: a prospective controlled, randomized clinical trial. Nutrition. 2015;31:171-175.
- 13. Huang W, de la Iglesia-García D, Baston-Rey I, et al. Exocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis. Dig Dis Sci. 2019;64:1985-2005.
There are 13 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | Case Report |
| Authors | |
| Publication Date | December 31, 2020 |
| Acceptance Date | September 15, 2020 |
| Published in Issue | Year 2020 Volume: 3 Issue: 3 |
