Abstract
Abstract
Aluminum phosphite is a chemical used as an insecticide and pesticide to improve the storage conditions of agricultural products. Combined with the humidity in the air or after being taken orally as a tablet, it reacts with the acidic environment of the stomach and turns into phosphine gas and can cause poisoning. Suicidal use is also common. When poisoning develops, deep metabolic acidosis, hypotensive shock, acute respiratory failure, multi-organ failure, cardiac arrest and death may occur. Resistant hypotension and deep metabolic acidosis are the most important indicators of poor prognosis. In this case, an 18 year old male patient was brought to the emergency room after taking 3 tablets of aluminum phosphide. The patient was unconscious and had hypotensive shock. Despite gastric lavage, massive fluid replacement, positive inotropes, sodium bicarbonate, intravenous N acetyl cysteine loading, and hemodialysis, the patient died 6 hours after admission to the emergency department.
References
- Tolunay O., Çelik T., Yücel G., Özdemir U., Atmış A., Sucu A. et al. A Rare but Deadly Poisoning: Aluminum Phosphide Poisoning. J Pediatr Emerg Intensive Care Med, 2017;4:27-9.
- Ekinci F., Dinçer R., Horoz Ö.Ö., Kendir Ö.T., Petmezci E., Tolunay İ et al. Aluminum phosphide poisoning: two pediatric cases and two separate clinical outcomes. J Pediatr Emerg Intensive Care Med. 2017;4:72-6.
- Hakimoğlu S., Dikey İ., Sarı A., Kekeç L., Tuzcu K., Karcıoğlu, M. Successful management of aluminum phosphide poisoning resulting in cardiac arrest. Turk J Anaesth Reanim. 2015;43:288-290.
- Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4:378-84.
- Yalçın D. , Candan B. F. , Mutlu M. , Yelken B. A Rare Case of Aluminum Phosphite Inhalation Intoxication. Eskisehir Med J. 2022; 3(2): 234-238.
- Belen V. K. , Yoldaş A. , Karakuş A. Aluminum phosphide poisoning. Eurasian Journal of Toxicology. 2022; 4(1):27-28.
- Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum phosphide poisoning related deaths in Tehran, Iran, 2006 to 2013. Medicine. 2015;94(38):e1637.
- Chaudry D, Rai AS. N-acetyl cysteine in aluminum phosphide poisoning: Myth or hope. Indian J Crit Care Med. 2014;18:646-7.
- Bogle R.G., Theron, P., Brooks P., Dargan P.I., Redhead J. Aluminum phosphide poisoning. Emerg Med J. 2006;23:3.
- Terece C., Soğukpınar V. O., Özdemir N., Polat S. Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used: Case Report. Eurasian J Tox. 2019; 1(1): 33- 36.
Abstract
Özet: Alüminyum fosfit, tarım ürünlerinin saklama koşullarını iyileştirmek amacıyla insektisit ve pestisit olarak olarak kullanılan bir kimyasal maddedir. Havadaki nemle birleşerek ya da tablet olarak ağızdan alındıktan sonra midenin asidik ortamı ile tepkimeye girerek fosfin gazına dönüşür ve zehirlenmeye neden olabilir. İntihar amaçlı kullanımı da yaygın görülmektedir. Zehirlenme geliştiğinde derin metabolik asidoz, hipotansif şok, akut solunum yetmezliği, çoklu organ yetmezliği, kardiyak arrest ve ölüm görülebilir. Dirençli hipotansiyon ve derin metabolik asidoz kötü prognozun en önemli belirteçleridir. Bu vakada 18 yaşında erkek hasta acil servise 3 tablet alüminyum fosfit alımı sonrası getirilmiştir. Hastada bilinç kapalı ve hipotansif şok mevcuttu. Hastaya mide yıkama, masif sıvı replasmanı, pozitif inotroplar, sodyum bikarbonat, intravenöz N asetil sistein yüklemesi ve hemodiyaliz yapılmasına rağmen acil servise başvurudan 6 saat sonra ölümle sonuçlandı.
References
- Tolunay O., Çelik T., Yücel G., Özdemir U., Atmış A., Sucu A. et al. A Rare but Deadly Poisoning: Aluminum Phosphide Poisoning. J Pediatr Emerg Intensive Care Med, 2017;4:27-9.
- Ekinci F., Dinçer R., Horoz Ö.Ö., Kendir Ö.T., Petmezci E., Tolunay İ et al. Aluminum phosphide poisoning: two pediatric cases and two separate clinical outcomes. J Pediatr Emerg Intensive Care Med. 2017;4:72-6.
- Hakimoğlu S., Dikey İ., Sarı A., Kekeç L., Tuzcu K., Karcıoğlu, M. Successful management of aluminum phosphide poisoning resulting in cardiac arrest. Turk J Anaesth Reanim. 2015;43:288-290.
- Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4:378-84.
- Yalçın D. , Candan B. F. , Mutlu M. , Yelken B. A Rare Case of Aluminum Phosphite Inhalation Intoxication. Eskisehir Med J. 2022; 3(2): 234-238.
- Belen V. K. , Yoldaş A. , Karakuş A. Aluminum phosphide poisoning. Eurasian Journal of Toxicology. 2022; 4(1):27-28.
- Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum phosphide poisoning related deaths in Tehran, Iran, 2006 to 2013. Medicine. 2015;94(38):e1637.
- Chaudry D, Rai AS. N-acetyl cysteine in aluminum phosphide poisoning: Myth or hope. Indian J Crit Care Med. 2014;18:646-7.
- Bogle R.G., Theron, P., Brooks P., Dargan P.I., Redhead J. Aluminum phosphide poisoning. Emerg Med J. 2006;23:3.
- Terece C., Soğukpınar V. O., Özdemir N., Polat S. Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used: Case Report. Eurasian J Tox. 2019; 1(1): 33- 36.
Details
| Primary Language | English |
|---|---|
| Subjects | Toxicology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 30, 2023 |
| Submission Date | January 11, 2023 |
| Published in Issue | Year 2023 Volume: 5 Issue: 1 |
Cite
Dizinler ve Platformlar