Research Article
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Psoriasisli çocuk hastaların klinik ve demografik özelliklerinin retrospektif olarak değerlendirilmesi

Year 2019, Volume: 16 Issue: 2, 321 - 325, 29.08.2019
https://doi.org/10.35440/hutfd.491500

Abstract

 

Amaç:
Psoriasis immün aracılı inflamatuar bir dermatoz olup, pediatrik dermatozların
%4’ünü oluşturur. Çalışmamızda, psoriasisli çocuklarda klinik ve demografik
özelliklerin değerlendirilmesi amaçlanmıştır.

Materyal ve Metot:
Çalışmaya, 70 psoriasisli çocuk hasta alındı. Yaş, cinsiyet, hastalık başlangıç
yaşı, eklem veya tırnak tutulumu, klinik tip, lezyon dağılımı, hastalık
şiddeti, aile öyküsü, eşlik eden hastalık, alınmış/alınmakta olan tedaviler,
sigara kullanımıyla beden kitle indeksi parametreleri kaydedildi. Veriler
istatistiksel olarak analiz edildi.

Bulgular:
Hastaların 36’sı kız (%51.4), 34’ü erkekti (%48.5). Kız/erkek oranı 1.058/1
idi. Ortalama başlangıç yaşı 8.01±4.56 idi. En sık başlangıç yaş aralığı 0-5
idi (%34.28). Aile öyküsü %31.40’ünde, eşlik eden hastalık %8.57’sinde, eklem
tutulumu %10’unda, tırnak tutulumu %18.57’sinde ve sigara kullanımı %8.57’sinde
mevcuttu. En sık klinik tip plak tip (%68.57), en sık yerleşim yeri saçlı
deri/yüz bölgesi (%74.28) ve en sık kullanılan sistemik ajan metotreksat idi
(%18.57).

Sonuç:
Sonuçlarımız, önceki çalışma sonuçlarıyla çoğunlukla uyumluydu. Klinik tipler
sırasıyla plak, guttat, palmoplantar ve püstüler olup, hiçbir hastada
eritrodermik forma rastlanmadı. Kız hastalarda palmoplantar tutulum gözlenmedi.
Hastaların %45.71’inde hafif, %24.28’inde orta şiddetli ve %30’unda şiddetli
psoriasis mevcuttu. İki hastada vitiligo mevcuttu.

Literatürde
çocukluk çağı psoriasis hastalarının klinik ve sosyodemografik özelliklerini
değerlendiren çalışma sayısı az olup, veriler oldukça değişkendir. Çalışma
sonuçlarımızı daha iyi değerlendirebilmek için, ileri çalışmalara ihtiyaç
olduğu kanaatindeyiz.













 

References

  • 1. Yesilova Y, Yavuz E, Sula B. The sensitivity of patch test in patients with psoriasis. Dicle Med J 2010; 37: 236-40.
  • 2. Ozden MG. Childhood psoriasis. Turkderm 2011; 45: 127-32.
  • 3. Kose N, Kutlugun C. Measurement of bone mineral density in patients with psoriasis vulgaris. Dicle Med J 2013; 40: 621-6.
  • 4. Karadag AS, Gunes Bilgili S, Calka O, Tas Demircan Y. The Retro spective evaluation of childhood psoriasis clinically and demographic features. Turk J Dermatol 2013; 7: 13-7.
  • 5. NB Silverberg. Pediatric psoriasis: an update. Therapeutics and Clinical Risk Management 2009; 5: 849-56.
  • 6. Bukulmez G, Ersoy S, Atakan N, Saray Y. K, Şahin S, Karaduman A. et al. Clinical features of childhood psoriasis: a retrospective study of 117 cases. Turkderm 2001; 35: 43-5.
  • 7. Seyhan M, Coskun BK, Saglam H, Ozcan H, Karincaoglu Y. Psoriasis in childhood and adolescence: evaluation of demographic and clinical features. Pediatr Int 2006; 48: 525-30.
  • 8. I. M. G. J. Bronckers, A. S. Paller, M. J. Van Geel, P. C. M. Van de Kerkhof, M. M. B. Seyger. Psoriasis in adolescents and children: diagnosis, management and comorbidities. Pediatr Drugs 2015; 17: 373-384.
  • 9. Stefanaki C, Lagogianni E, Kontochristopoulos G, Verra P, Barkas G, Katsambas A. et al. Psoriasis in children: a retrospective analysis. J Eur Acad Dermatol Venereol 2011; 25: 417-21.
  • 10. Kumar B, Jain R, Sandhu K, Kaur I, Handa S. Epidemiology of childhood psoriasis: a study of 419 patients from northern India. Int J Dermatol 2004; 43: 654-8.
  • 11. Morris A, Rogers M, Fischer G, Williams K. Childhood psoriasis: a clinical review of 1262 cases. Pediatr Dermatol 2001; 18: 188-98.
  • 12. Ozden MG, Tekin NS, Gurer MA, Akdemir D, Doğramacı Ç, Utaş S. et al. Environmental risk factors in pediatric psoriasis: a multicenter a case-controlstudy. Pediatr Dermatol 2011; 28: 306-12.
  • 13. Augustin M, Glaeske G, Radtke MA, Christophers E, Reich K, Schafer I. Epidemiology and comorbidity of psoriasis in children. Br J Dermatol 2010; 162: 633-6.
  • 14. Lee EJ, Han KD, Han JH, Lee JH. Smoking and risk of psoriasis: a nationwide cohort study. J Am Acad Dermatol 2017; 77: 573-5.
  • 15. Barton AC. Genetic epidemiology. Psoriatic arthritis. Arthritis Res 2002; 4: 247-51.
  • 16. Diluvio L, Campione E, Paterno EJ, Mordenti C, El Hachem M, Chimenti S. Childhood nail psoriasis: a usefull treatment with tazarotene 0.05%. Pediatr Dermatol 2007; 24: 332-3.
  • 17. Salomon J, Szepietovski JC, Proniewicz A. Psoriatic nails: A prospective clinical study. J Cutan Med Surg 2003; 7: 317-21.

The retrospective evaluation of clinical and demographic features of children with psoriasis

Year 2019, Volume: 16 Issue: 2, 321 - 325, 29.08.2019
https://doi.org/10.35440/hutfd.491500

Abstract

Background:
Psoriasis is an immune-mediated inflammatory dermatosis and constitutes 4% of
the pediatric dermatosises. In our study, evaluation of the clinical and
demographic characteristics of children with psoriasis has been aimed.

Methods: 70 children with
psoriasis were included to the study. Parameters such as age, gender, disease,
age of onset, joint or nail involvement, clinical type, distribution of
lesions, severity of the disease, family history, accompanying disease,
received/receiving treatments, smoking habits and body mass index were
recorded. The data were statistically analyzed.

Results: 36 of the patients
were girls (51.4%) and girl/boy ratio was: 1.058/1. Average age of onset was
8.01±4.56. The most frequent age of onset was 0-5 (%34.28). 31.40% of the
patients had family history, 8.57% of them had accompanying disease, 10% of
them had joint involvement, 18.57% of them had nail involvement and 8.57% of
them were smoking. The most frequent clinical type was plaque type (68.57%),
the most frequent parts that the disease was observed were hairy skin/face
areas (74.28%), and the most frequently used systemic agent was methotrexate
(18.57%).

Conclusion:
Our results were mostly compatible with previous study results. In literature,
the amounts of studies that evaluate the clinic and sociodemographic
characteristics of the children with psoriasis are few and data are quite
variational.









 

References

  • 1. Yesilova Y, Yavuz E, Sula B. The sensitivity of patch test in patients with psoriasis. Dicle Med J 2010; 37: 236-40.
  • 2. Ozden MG. Childhood psoriasis. Turkderm 2011; 45: 127-32.
  • 3. Kose N, Kutlugun C. Measurement of bone mineral density in patients with psoriasis vulgaris. Dicle Med J 2013; 40: 621-6.
  • 4. Karadag AS, Gunes Bilgili S, Calka O, Tas Demircan Y. The Retro spective evaluation of childhood psoriasis clinically and demographic features. Turk J Dermatol 2013; 7: 13-7.
  • 5. NB Silverberg. Pediatric psoriasis: an update. Therapeutics and Clinical Risk Management 2009; 5: 849-56.
  • 6. Bukulmez G, Ersoy S, Atakan N, Saray Y. K, Şahin S, Karaduman A. et al. Clinical features of childhood psoriasis: a retrospective study of 117 cases. Turkderm 2001; 35: 43-5.
  • 7. Seyhan M, Coskun BK, Saglam H, Ozcan H, Karincaoglu Y. Psoriasis in childhood and adolescence: evaluation of demographic and clinical features. Pediatr Int 2006; 48: 525-30.
  • 8. I. M. G. J. Bronckers, A. S. Paller, M. J. Van Geel, P. C. M. Van de Kerkhof, M. M. B. Seyger. Psoriasis in adolescents and children: diagnosis, management and comorbidities. Pediatr Drugs 2015; 17: 373-384.
  • 9. Stefanaki C, Lagogianni E, Kontochristopoulos G, Verra P, Barkas G, Katsambas A. et al. Psoriasis in children: a retrospective analysis. J Eur Acad Dermatol Venereol 2011; 25: 417-21.
  • 10. Kumar B, Jain R, Sandhu K, Kaur I, Handa S. Epidemiology of childhood psoriasis: a study of 419 patients from northern India. Int J Dermatol 2004; 43: 654-8.
  • 11. Morris A, Rogers M, Fischer G, Williams K. Childhood psoriasis: a clinical review of 1262 cases. Pediatr Dermatol 2001; 18: 188-98.
  • 12. Ozden MG, Tekin NS, Gurer MA, Akdemir D, Doğramacı Ç, Utaş S. et al. Environmental risk factors in pediatric psoriasis: a multicenter a case-controlstudy. Pediatr Dermatol 2011; 28: 306-12.
  • 13. Augustin M, Glaeske G, Radtke MA, Christophers E, Reich K, Schafer I. Epidemiology and comorbidity of psoriasis in children. Br J Dermatol 2010; 162: 633-6.
  • 14. Lee EJ, Han KD, Han JH, Lee JH. Smoking and risk of psoriasis: a nationwide cohort study. J Am Acad Dermatol 2017; 77: 573-5.
  • 15. Barton AC. Genetic epidemiology. Psoriatic arthritis. Arthritis Res 2002; 4: 247-51.
  • 16. Diluvio L, Campione E, Paterno EJ, Mordenti C, El Hachem M, Chimenti S. Childhood nail psoriasis: a usefull treatment with tazarotene 0.05%. Pediatr Dermatol 2007; 24: 332-3.
  • 17. Salomon J, Szepietovski JC, Proniewicz A. Psoriatic nails: A prospective clinical study. J Cutan Med Surg 2003; 7: 317-21.
There are 17 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Article
Authors

Mahmut Demir 0000-0002-0983-9457

Mustafa Aksoy 0000-0002-4303-699X

Publication Date August 29, 2019
Submission Date December 3, 2018
Acceptance Date May 10, 2019
Published in Issue Year 2019 Volume: 16 Issue: 2

Cite

Vancouver Demir M, Aksoy M. The retrospective evaluation of clinical and demographic features of children with psoriasis. Harran Üniversitesi Tıp Fakültesi Dergisi. 2019;16(2):321-5.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty