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Year 2019, Volume: 3 Issue: 1, 72 - 76, 28.06.2019

Hüseyin Akşit Mehmet Keçeci İbrahim Demirtaş Nusret Genç

https://doi.org/10.32571/ijct.577183
Cited By: 3

Abstract

References

  • 1. Erenler, R.; Telci, I.; Elmastaş, M.; Akşit, H.; Gül, F.; Tüfekçi, A. R.; Kayır, Ö. Turk. J. Chem. 2018, 42(6), 1695-1705.
  • 2. Karan, T.; Erenler, R. Trop. J. Pharm. Res. 2018, 17(10), 1977-1982.
  • 3. Erenler, R.; Demirtaş, I.; Karan, T.; Gül, F.; Kayır, O.; Karakoc, O. C. Trends Phytochem. Res. 2018, 2(2), 91-96.
  • 4. Karan, T.; Yıldız, I.; Aydın, A.; Erenler, R.; Rec. Nat. Prod. 2018, 12(3), 273-283.
  • 5. Karan, T.; Erenler, R. Pharmacogn. Mag. 2017, 13, 723-725.
  • 6. Güzel, A.; Akşit, H.; Elmastaş, M.; Erenler, R. Pharmacogn. Mag. 2017, 13(50), 316-320.
  • 7. Erenler, R.; Meral, B.; Şen, Ö.; Elmastaş, M.; Aydın, A.; Eminağaoğlu, O.; Topçu, G. Pharm. Biol. 2017, 55(1), 1646-1653.
  • 8. Erenler, R.; Şen, Ö.; Şahin Yağlıoğlu, A.; Demirtaş, I.; Comb. Chem. High T. Scr. 2016, 19(1), 66-72. 9. Capecka, E.; Mareczek, A.; Leja, M. Food Chem. 2005, 93, 223-226.
  • 10. Kwee, E. M.; and Niemeyer, E. D. Food Chem. 2011, 128, 1044-1050.
  • 11. Sharmila, R.; Manoharan, S. Indian J. Exp. Biol. 2012, 50, 187-194.
  • 12. Jiang, W. L.; Xu, Y.; Zhang, S. P.; Hou, J.; Zhu, H. B. Basic Clin. Pharmacol. Toxicol, 2012, 110, 390-395.
  • 13. Perez-Tortosa, V.; Lopez-Orenes, A.; Martinez-Perez, A.; Ferrer, M.A.; Calderon, A.A. Food Chem. 2012, 130, 362-369.
  • 14. Erenler, R.; Şen, Ö.; Yıldız, I.; Aydın, A. Rec. Nat. Prod. 2016, 10(6), 766-770.
  • 15. Zhang, J. J.; Wang, Y. L.; Feng, X. B.; Song, X. D.; Lu, W.B. Biol. Pharm. Bull. 2011, 34, 343-348.
  • 16. Swarup, V.; Ghosh, J.; Ghosh, S.; Saxena, A.; Basu, A. Antimicrob. Agents Ch. 2007, 51, 3367-3370.
  • 17. Erenler, R.; Yılmaz, S.; Akşit, H.; Sen, O.; Genç, N.; Elmastaş, M.; Demirtaş. İ. Rec. Nat. Prod. 2014 8(1), 32-36.
  • 18. Erenler, R., Telci, I., Ulutaş, M., Demirtaş, I., Gül, F., Elmastaş, M., Kayır, Ö. J. Food Biochem. 2015, 39(5), 622-630.
  • 19. Grice, H. C. Food Chem. Toxicol. 1986, 24, 1127-1130.
  • 20. Demirtaş, İ.; Erenler, R.; Elmastaş, M.; Göktaşoğlu, A. Food Chem. 2013, 136, 34-40.
  • 21. Woo E. R.; Piao, M. S. Arch. Pharm. Res. 2007, 27, 173-176.
  • 22. Wang, M. F.; Li, J. G.; Rangarajan, M.; Shao, Y.; LaVoie, E. J.; Huang T.C.; Ho, C. T. J. Agr. Food Chem. 1998, 46, 4869-4873.

Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography

Year 2019, Volume: 3 Issue: 1, 72 - 76, 28.06.2019

Hüseyin Akşit Mehmet Keçeci İbrahim Demirtaş Nusret Genç

https://doi.org/10.32571/ijct.577183
Cited By: 3

Abstract

In this study; it was aimed at
the isolation of rosmarinic acid (RosA) from Ocimum basilicum (OB) with
a selective extraction and rapid isolation technique using flash chromatography
(FC). For this purpose, dried leaves of OB were extracted with n-hexane,
dichloromethane, and methanol, respectively. The methanol extract (ME) was
extracted with dichloromethane and ethyl acetate using separation funnel by
suspending with water. The ethyl acetate layer was dried with anhydrous Na2SO4
and the solvent was evaporated to give a rosmarinic acid-rich extract. Then the
ethyl acetate extract (EAE) was separated over silica gel column using FC, and
thus RosA was isolated with high purity. 

Keywords

Rosmarinic acid flash chromatography Ocimum basilicum

References

  • 1. Erenler, R.; Telci, I.; Elmastaş, M.; Akşit, H.; Gül, F.; Tüfekçi, A. R.; Kayır, Ö. Turk. J. Chem. 2018, 42(6), 1695-1705.
  • 2. Karan, T.; Erenler, R. Trop. J. Pharm. Res. 2018, 17(10), 1977-1982.
  • 3. Erenler, R.; Demirtaş, I.; Karan, T.; Gül, F.; Kayır, O.; Karakoc, O. C. Trends Phytochem. Res. 2018, 2(2), 91-96.
  • 4. Karan, T.; Yıldız, I.; Aydın, A.; Erenler, R.; Rec. Nat. Prod. 2018, 12(3), 273-283.
  • 5. Karan, T.; Erenler, R. Pharmacogn. Mag. 2017, 13, 723-725.
  • 6. Güzel, A.; Akşit, H.; Elmastaş, M.; Erenler, R. Pharmacogn. Mag. 2017, 13(50), 316-320.
  • 7. Erenler, R.; Meral, B.; Şen, Ö.; Elmastaş, M.; Aydın, A.; Eminağaoğlu, O.; Topçu, G. Pharm. Biol. 2017, 55(1), 1646-1653.
  • 8. Erenler, R.; Şen, Ö.; Şahin Yağlıoğlu, A.; Demirtaş, I.; Comb. Chem. High T. Scr. 2016, 19(1), 66-72. 9. Capecka, E.; Mareczek, A.; Leja, M. Food Chem. 2005, 93, 223-226.
  • 10. Kwee, E. M.; and Niemeyer, E. D. Food Chem. 2011, 128, 1044-1050.
  • 11. Sharmila, R.; Manoharan, S. Indian J. Exp. Biol. 2012, 50, 187-194.
  • 12. Jiang, W. L.; Xu, Y.; Zhang, S. P.; Hou, J.; Zhu, H. B. Basic Clin. Pharmacol. Toxicol, 2012, 110, 390-395.
  • 13. Perez-Tortosa, V.; Lopez-Orenes, A.; Martinez-Perez, A.; Ferrer, M.A.; Calderon, A.A. Food Chem. 2012, 130, 362-369.
  • 14. Erenler, R.; Şen, Ö.; Yıldız, I.; Aydın, A. Rec. Nat. Prod. 2016, 10(6), 766-770.
  • 15. Zhang, J. J.; Wang, Y. L.; Feng, X. B.; Song, X. D.; Lu, W.B. Biol. Pharm. Bull. 2011, 34, 343-348.
  • 16. Swarup, V.; Ghosh, J.; Ghosh, S.; Saxena, A.; Basu, A. Antimicrob. Agents Ch. 2007, 51, 3367-3370.
  • 17. Erenler, R.; Yılmaz, S.; Akşit, H.; Sen, O.; Genç, N.; Elmastaş, M.; Demirtaş. İ. Rec. Nat. Prod. 2014 8(1), 32-36.
  • 18. Erenler, R., Telci, I., Ulutaş, M., Demirtaş, I., Gül, F., Elmastaş, M., Kayır, Ö. J. Food Biochem. 2015, 39(5), 622-630.
  • 19. Grice, H. C. Food Chem. Toxicol. 1986, 24, 1127-1130.
  • 20. Demirtaş, İ.; Erenler, R.; Elmastaş, M.; Göktaşoğlu, A. Food Chem. 2013, 136, 34-40.
  • 21. Woo E. R.; Piao, M. S. Arch. Pharm. Res. 2007, 27, 173-176.
  • 22. Wang, M. F.; Li, J. G.; Rangarajan, M.; Shao, Y.; LaVoie, E. J.; Huang T.C.; Ho, C. T. J. Agr. Food Chem. 1998, 46, 4869-4873.
There are 21 citations in total.

Details

Primary Language English
Subjects Chemical Engineering
Journal Section Short Communication
Authors

Hüseyin Akşit 0000-0002-1509-851X

Mehmet Keçeci This is me 0000-0002-0420-5316

İbrahim Demirtaş 0000-0001-8946-647X

Nusret Genç 0000-0003-3685-1344

Publication Date June 28, 2019
Published in Issue Year 2019 Volume: 3 Issue: 1

Cite

APA Akşit, H., Keçeci, M., Demirtaş, İ., Genç, N. (2019). Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography. International Journal of Chemistry and Technology, 3(1), 72-76. https://doi.org/10.32571/ijct.577183
AMA Akşit H, Keçeci M, Demirtaş İ, Genç N. Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography. Int. J. Chem. Technol. June 2019;3(1):72-76. doi:10.32571/ijct.577183
Chicago Akşit, Hüseyin, Mehmet Keçeci, İbrahim Demirtaş, and Nusret Genç. “Rapid Isolation of Rosmarinic Acid from Ocimum Basilicum Using Flash Chromatography”. International Journal of Chemistry and Technology 3, no. 1 (June 2019): 72-76. https://doi.org/10.32571/ijct.577183.
EndNote Akşit H, Keçeci M, Demirtaş İ, Genç N (June 1, 2019) Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography. International Journal of Chemistry and Technology 3 1 72–76.
IEEE H. Akşit, M. Keçeci, İ. Demirtaş, and N. Genç, “Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography”, Int. J. Chem. Technol., vol. 3, no. 1, pp. 72–76, 2019, doi: 10.32571/ijct.577183.
ISNAD Akşit, Hüseyin et al. “Rapid Isolation of Rosmarinic Acid from Ocimum Basilicum Using Flash Chromatography”. International Journal of Chemistry and Technology 3/1 (June 2019), 72-76. https://doi.org/10.32571/ijct.577183.
JAMA Akşit H, Keçeci M, Demirtaş İ, Genç N. Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography. Int. J. Chem. Technol. 2019;3:72–76.
MLA Akşit, Hüseyin et al. “Rapid Isolation of Rosmarinic Acid from Ocimum Basilicum Using Flash Chromatography”. International Journal of Chemistry and Technology, vol. 3, no. 1, 2019, pp. 72-76, doi:10.32571/ijct.577183.
Vancouver Akşit H, Keçeci M, Demirtaş İ, Genç N. Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography. Int. J. Chem. Technol. 2019;3(1):72-6.

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