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Antioxidant and antimicrobial activities of the essential oil of Helichrysum chionophilum: an endemic plant of Türkiye

Year 2023, Volume: 13 Issue: 2, 680 - 689, 15.06.2023

Tuba Acet Kadriye Özcan

https://doi.org/10.31466/kfbd.1271087
Cited By: 1

Abstract

Diseases that develop due to microorganisms have become increasingly dangerous today. Especially in the fight against resistant microorganisms, there is a need for cheaper, natural and effective methods. Plant materials containing biologically active compounds come to the fore in this sense. Therefore, in the present study, the antioxidant and antimicrobial activities of the essential oil obtained from H. chionophilum collected from Gümüşhane were investigated. The essential oil was obtained by hydro-distillation using a Clevenger-type apparatus. Free radical scavenging activity was determined using the DPPH (2,2-diphenyl-1-picrylhydrazil) method. Antimicrobial activity was examined using the microdilution method using 17 bacteria and 2 yeasts. According to the findings, IC50 value of the radical scavenging activity of the essential oil of H. chionophilum plant was found to be 260.0±0.2 µg/mL. Also, the essential oil of the plant showed outstanding antimicrobial activity against Y. pseudotuberculosis (MIC: 16 µg/mL), S. epidermidis (MIC: 16 µg/mL), and C. albicans (MIC: 16 µg/mL) and C. tropicalis (MIC: 32 µg/mL). The results indicate that H. chionophilum, which is an endemic species, and its essential oils can be used as a new and alternative natural agent thanks to its antioxidant and antimicrobial properties.

Keywords

Antioxidant antimicrobial Helichrysum chionophilum

References

  • Acet, T., and Özcan, K. (2022). Heracleum pastinacifolium’nın antioksidan ve antimikrobiyal özellikleri ile fenolik içeriğinin aydınlatılması. Karadeniz Fen Bilimleri Dergisi, 12(1), 22-32.
  • Acet, T., Ozcan, K., and Zengin, G., (2020). An assessment of phenolic profiles, fatty acid compositions, and biological activities of two Helichrysum species: H. plicatum and H. chionophilum. Journal of Food Biochemisrty. 44, e13128.
  • Afoulous, S., Ferhout, H., Raoelison, E.G., Valentin, A., Moukarzel, B., Couderc, F., and Bouajila, J., (2011). Helichrysum gymnocephalum Essential oil: chemical composition and cytotoxic, antimalarial and antioxidant activities, attribution of the activity origin by correlations. Molecules, 16(10), 8273-8291.
  • Akinfenwa, A.O., Sagbo, I.J., Makhaba, M., Mabusela, W.T., and Hussein, A.A., (2022). Helichrysum genus and compound activities in the management of diabetes mellitus. Plants (Basel), 23, 11(10), 1386.
  • Albayrak, S., Aksoy, A., Sağdiç, O., and Budak, Ü., (2010). Phenolic compounds and antioxidant and antimicrobial properties of Helichrysum species collected from eastern Anatolia, Turkey. Turkish Journal of Biology, 34, 463-473.
  • Aslan, M., Orhan, D.D., Orhan, N., Sezik, E., and Yesilada, E., (2007). In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats. Journal of Ethnopharmacology, 109(1), 54-59.
  • Başer, K.H.C., Demirci, B., and Kirimer, N., (2002). Compositions of the essential oils of four Helichrysum species from Madagascar. Journal of Essential Oil Research, 14(1), 53-55.
  • Baytop, T., (1997). Türkçe bitki adiarı sözlüğü (A dictionary ofvernacular names of wild plants of Turkey) (p. 578). Ankara: Publication of the Turk Dil Kurumu (The Turkish Language Society).
  • Benelli, G., Pavela, R., Rakotosaona, R., Randrianarivo, E., Nicoletti, M., and Maggi, F., (2018). Chemical composition and insecticidal activity of the essential oil from Helichrysum faradifani endemic to Madagascar. Natural Product Research, 32(14), 1690-1698.
  • Bianchini, A., Santoni, F., Paolini, J., Bernardini, A.F., Mouillot, D., and Costa, J., (2009). Partitioning the relative contributions of inorganic plant composition and soil characteristics to the quality of Helichrysum italicum subsp. italicum (Roth) G. Don fil. essential oil. Chemistry and Biodiversity, 6(7), 1014-33.
  • Cantore, L.P., Iacobellis, S.N., Marco, D.A., Capasso, F., and Senatore, F., (2004). Antibacterial activity of Coriandrum sativum L. and Foeniculum vulgare Miller var. (MILLER) Essential oil. Journal of Agricultural and Food Chemistry, 7862-7866.
  • Chalchat J.C., and Özcan, M.M., (2006). Composition of the essential oil of Helichrysum chasmolycicum growing wild in Turkey. Journal of Medicinal Food, 9(2), 287-289.
  • Chinou, L.B., Bougatsos, C., and Perdetzoglou, D., (2004). Chemical composition and antimicrobial activities of Helichrysum amorginum cultivated in Greece. Journal of Essential Oil Research, 16(3), 243-245.
  • Clinical and Laboratory Standards Institute (CLSI), (2017). Performance Standards for Antimicrobial Susceptibility Testing; 27th Informational Supplement. CLSI/NCCLS, 27th ed.; Clinical and Laboratory Standards Institute: Wayne, PA, USA.
  • Davis, P.H., Mill R.R. and Tan, K., (1988). Flora of Turkey and the East Aegean Islands. Edinburgh University Press. Edinburgh, UK.
  • Djihane, B., Wafa, N., Elkhamssa, S., Pedro, D.H.J., Maria, A.E., and Mihoub, Z.M., (2017). Chemical constituents of Helichrysum italicum (Roth) G. Don essential oil and their antimicrobial activity against Gram-positive and Gram-negative bacteria, filamentous fungi and Candida albicans. Saudi Pharmaceutical Journal, 25, 780-787.
  • Ebrahimzadeh, M.A., and Tavassoli, A., (2015). Antioxidant properties of Helichrysum pseudoplicatum Nab. Pharmaceutical and Biomedical Research, 1(1), 37.
  • Ebrahimzadeh, M.A., Nabavi, S.F., Nabavi, S.M., and Eslami, B., (2010). Antihemolytic and antioxidant activities of Allium paradoxum. Central European Journal of Biology, 5, 338-345.
  • El-Olemy, M.M., Al-Rehaily, A.J., Albishi, O.A., Mossa, J.S., Demirci B., and Başer, K.H.C., (2005). Composition of the Essential Oil of Helichrysum forsskahlii (Gmel) Hilliard et Burt. Journal of Essential Oil Research, 17(1), 112-116.
  • Furlan, V., and Bren, U., (2023). Helichrysum italicum: From extraction, distillation, and encapsulation techniques to beneficial health effects. Foods, 12(4), 802.
  • Giovanelli, S., De Leo, M., Cervelli, C., Ruffoni, B., Ciccarelli, D., and Pistelli, L., (2018). Essential oil composition and volatile profile of seven Helichrysum species grown in Italy. Chemistry and Biodiversity, 15, e1700545.
  • Giuliani, C., Lazzaro, L., Calamassi, R., Calamai, L., Romoli, R., Fico, G., Foggi, B., and Lippi, M.M., (2016). A volatolomic approach for studying plant variability: the case of selected Helichrysum species (Asteraceae). Phytochemistry, 130, 128-143.
  • González, A.M., Tracanna, M.I., Amani, S.M., Schuff, C., Poch, M.J., Bach, H., and Can, C., (2012). Chemical composition, antimicrobial and antioxidant properties of the volatile oil and methanol extract of Xenophyllum poposum. Natural Product Communications, 7(12), 1663-1666.
  • Güner, A., S. Aslan, T. Ekim, M. Vural ve M. T. Babaç, 2012. Türkiye Bitkileri Listesi (Damarlı Bitkiler). Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını, İstanbul.
  • Javidnia, K., Miri, R., Soltani M., and Khosravi, A.R., (2009). Essential oil composition of two Iranian endemic Helichrysum Miller. species (H. leucocephalum Boiss. and H. artemisioides Boiss. et Hausskn.). Journal of Essential Oil Research, 21(1), 54-56.
  • Jokić, S., Rajić, M., Bilić, B., and Molnar, M., (2016). Supercritical extraction of scopoletin from Helichrysum italicum (Roth) G. Don flowers. Phytochemical Analysis, 27, 290-295.
  • Judzentiene, A., and Butkiene, R., (2006). Chemical composition of the essential oils of wild Helichrysum arenarium (L.) with differently colored inflorescences from Eastern Lithuania. Journal of Essential Oil Research, 18(1), 80-83.
  • Judžentienė, A., Charkova, T., and Misiūnas, A., (2019). Chemical composition of the essential oils from Helichrysum arenarium (L.) plants growing in Lithuanian forests. Journal of Essential Oil Research, 31(4), 305-311.
  • Kladar, N.V., Anačkov, G.T., Rat, M.M., Srđenović, B.U., Grujić, N.N., Šefer, E.L., and Božin, B.N., (2015). Biochemical characterization of Helichrysum italicum (Roth) G.Don subsp. italicum (Asteraceae) from Montenegro: phytochemical screening, chemotaxonomy, and antioxidant properties. Chemistry and Biodiversity, 12(3), 419-31.
  • Kürkçüoğlu, M., Ağalar, H.G., Aksoy A., and Başer, K.H.C., (2019). Composition of the essential oils of two endemic Helichrysum species in Turkey. Records of Natural Products, 13(3), 236-242.
  • Kurti, F., Giorgi, A., Beretta, G., Mustafa, B., Gelmini, F., Testa, C., Angioletti, S., Giupponi, L., Zilio, E., Pentimalli, D., and Hajdari, A., (2019). Chemical composition, antioxidant and antimicrobial activities of essential oils of different Pinus species from Kosovo. Journal of Essential Oil Research, 31(4), 263-275.
  • Lourens, A.C.U., Reddy, D., Baser, K.H.C., Viljoen, A.M., and Van Vuuren, S.F., (2004). In vitro biological activity and essential oil composition of four indigenous South African Helichrysum Species. Journal of Ethnopharmacology, 95, 253-58.
  • Lourens, A.C.U., Viljoen, A.M., and van Heerden, F.R., (2008). South African Helichrysum species: A review of the traditional uses, biological activity and phytochemistry. Journal of Ethnopharmacology, 119(3), 630¬¬-652.
  • Ornano, L., Venditti, A., Sanna, C., Ballero, M., Maggi, F., Lupidi, G., Bramucci, M., Quassinti, L., and Bianco, A.C., (2015). Chemical composition and biological activity of the essential oil from Helichrysum microphyllum Cambess. ssp. tyrrhenicum Bacch., Brulloe Giusso growing in La Maddalena Archipelago. Sardinia, Journal of Oleo Science, 64(1), 19-26.
  • Özcan, K., and Acet, T., (2018b). Antimicrobial and antioxidant screening, synergy studies of Helichrysum chionophilum extracts against to resistant microbial strains. Fresenius Environmental Bulletin. 27(7), 5045-5052.
  • Özcan, K., and Acet, T., (2022). Stachys macrantha (K.Koch) Stearn’ın biyolojik aktivitesinin belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 11(1), 156-163.
  • Öztürk, B., Özek, G., Özek, T., and Baser, K.H.C., (2014). Chemical Diversity in Volatiles of Helichrysum plicatum DC. Subspecies in Turkey. Records of Natural Products, 8(4), 373-384.
  • Ralijerson, L.B., Rabehaja, D.J.R., Rajaonarison, J.F., Urverg, S.R., Hérent, M.F. Mavar-Manga, H., and Tilquin, B., (2005). Comparison between the fresh and dry essential oil of Helichrysum faradifani Scott Elliot from Madagascar. Journal of Essential Oil Research, 17(6), 597-600.
  • Rančić A., Soković, M., Vukojević, J., Simić, A., Marin, P., Duletić-Laušević, S., and Djoković, D., (2005). Chemical composition and antimicrobial activities of essential oils of Myrrhis odorata (L.) Scop, Hypericum perforatum L and Helichrysum arenarium (L.) Moench. Journal of Essential Oil Research, 17(3), 341-345.
  • Rossi, P.G., Berti, L., Panighi, J., Luciani, A., Maury, J., Muselli, A., De Rocca Serra, D., Gonny, M., and Bolla, J.M., (2007). Antibacterial action of essential oils from Corsica. Journal of Essential Oil Research, 19, 176-182.
  • Roussis, V., Tsoukatou, M., Chinou L.B., and Harvala, C., (2002). Composition and antibacterial activity of the essential oils of two Helichrysum stoechas varieties growing in the Island of Crete. Journal of Essential Oil Research, 14(6), 459-461.
  • Süzgeç-Selçuk, S., and Birteksöz, A.S., (2011). Flavonoids of Helichrysum chasmolycicum and its antioxidant and antimicrobial activities. South African Journal of Botany, 77(1), 170-174.
  • Tepe, B., Sokmen, M., Akpulat H.A., and Sokmen, A., (2005). In vitro antioxidant activities of the methanol extracts of four Helichrysum species from Turkey. Food Chemistry, 90(4), 685-689. van Vuuren, S.F., Viljoen, A.M., van Zyl, R.L., van Heerden, F.R., and Baser, K.H.C., (2006). The antimicrobial, antimalarial and toxicity profiles of helihumulone, leaf essential oil and extracts of Helichrysum cymosum (L.) D. Don subsp. cymosum. South African Journal of Botany, 72, 287-290.
  • Viegas, D.A., Palmeira-de-Oliveira, A., Salgueiro, L., Martinez-de-Oliveira, J., and Palmeira-de-Oliveira, R., (2014). Helichrysum italicum: From traditional use to scientific data. Journal of Ethnopharmacology, 151(1), 54-65.
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Helichrysum chionophilum’un uçucu yağının antioksidan ve antimikrobiyal aktiviteleri: Türkiye'nin endemik bir bitkisi

Year 2023, Volume: 13 Issue: 2, 680 - 689, 15.06.2023

Tuba Acet Kadriye Özcan

https://doi.org/10.31466/kfbd.1271087
Cited By: 1

Abstract

Mikroorganizmalara bağlı olarak gelişen rahatsızlıklar günümüzde giderek tehlikeli bir hal almıştır. Özellikle, dirençli organizmalar ile mücadele noktasında, daha ucuz, doğal ve etkili yöntemlere ihtiyaç duyulmaktadır. Biyolojik olarak aktif bileşikleri barındıran bitki materyalleri bu manada ön plana çıkmaktadır. Bu nedenle, mevcut çalışmada, Gümüşhane'den toplanan Helichrysum chionophilum'dan elde edilen uçucu yağın antioksidan ve antimikrobiyal aktiviteleri araştırılmıştır. Uçucu yağ, Clevenger tipi bir aparat kullanılarak hidro-damıtma yönteminden elde edildi. Serbest radikal yakalama aktivitesi, DPPH (2,2-difenil-1-pikrilhidrazil) yöntemi kullanılarak belirlendi. Antimikrobiyal aktivite mikro dilüsyon yöntemi kullanılarak 17 bakteri ve 2 maya kullanılarak incelendi. Elde edilen bulgulara göre, H. chionophilum bitkisi radikal süpürme aktivitesinin IC50 değeri 260.0±0.2 µg/mL olarak bulunmuştur. Ayrıca, bitkinin uçucu yağı, Y. pseudotuberculosis (MIC: 16 µg/mL), S. epidermidis (MIC: 16 µg/mL) ve C. albicans (MIC: 16 µg/mL) ve C. tropicalis'e (MIC: 32 µg/mL) karşı olağanüstü antimikrobiyal aktivite göstermiştir. Elde edilen sonuçlar, endemik bir tür olan H. chionophilum ve uçucu yağlarının antioksidan ve antimikrobiyal özellikleri sayesinde yeni ve alternatif doğal bir ajan olarak kullanılabileceğini işaret etmektedir.

Keywords

Antioksidan antimikrobiyal Helichrysum chionophilum

References

  • Acet, T., and Özcan, K. (2022). Heracleum pastinacifolium’nın antioksidan ve antimikrobiyal özellikleri ile fenolik içeriğinin aydınlatılması. Karadeniz Fen Bilimleri Dergisi, 12(1), 22-32.
  • Acet, T., Ozcan, K., and Zengin, G., (2020). An assessment of phenolic profiles, fatty acid compositions, and biological activities of two Helichrysum species: H. plicatum and H. chionophilum. Journal of Food Biochemisrty. 44, e13128.
  • Afoulous, S., Ferhout, H., Raoelison, E.G., Valentin, A., Moukarzel, B., Couderc, F., and Bouajila, J., (2011). Helichrysum gymnocephalum Essential oil: chemical composition and cytotoxic, antimalarial and antioxidant activities, attribution of the activity origin by correlations. Molecules, 16(10), 8273-8291.
  • Akinfenwa, A.O., Sagbo, I.J., Makhaba, M., Mabusela, W.T., and Hussein, A.A., (2022). Helichrysum genus and compound activities in the management of diabetes mellitus. Plants (Basel), 23, 11(10), 1386.
  • Albayrak, S., Aksoy, A., Sağdiç, O., and Budak, Ü., (2010). Phenolic compounds and antioxidant and antimicrobial properties of Helichrysum species collected from eastern Anatolia, Turkey. Turkish Journal of Biology, 34, 463-473.
  • Aslan, M., Orhan, D.D., Orhan, N., Sezik, E., and Yesilada, E., (2007). In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats. Journal of Ethnopharmacology, 109(1), 54-59.
  • Başer, K.H.C., Demirci, B., and Kirimer, N., (2002). Compositions of the essential oils of four Helichrysum species from Madagascar. Journal of Essential Oil Research, 14(1), 53-55.
  • Baytop, T., (1997). Türkçe bitki adiarı sözlüğü (A dictionary ofvernacular names of wild plants of Turkey) (p. 578). Ankara: Publication of the Turk Dil Kurumu (The Turkish Language Society).
  • Benelli, G., Pavela, R., Rakotosaona, R., Randrianarivo, E., Nicoletti, M., and Maggi, F., (2018). Chemical composition and insecticidal activity of the essential oil from Helichrysum faradifani endemic to Madagascar. Natural Product Research, 32(14), 1690-1698.
  • Bianchini, A., Santoni, F., Paolini, J., Bernardini, A.F., Mouillot, D., and Costa, J., (2009). Partitioning the relative contributions of inorganic plant composition and soil characteristics to the quality of Helichrysum italicum subsp. italicum (Roth) G. Don fil. essential oil. Chemistry and Biodiversity, 6(7), 1014-33.
  • Cantore, L.P., Iacobellis, S.N., Marco, D.A., Capasso, F., and Senatore, F., (2004). Antibacterial activity of Coriandrum sativum L. and Foeniculum vulgare Miller var. (MILLER) Essential oil. Journal of Agricultural and Food Chemistry, 7862-7866.
  • Chalchat J.C., and Özcan, M.M., (2006). Composition of the essential oil of Helichrysum chasmolycicum growing wild in Turkey. Journal of Medicinal Food, 9(2), 287-289.
  • Chinou, L.B., Bougatsos, C., and Perdetzoglou, D., (2004). Chemical composition and antimicrobial activities of Helichrysum amorginum cultivated in Greece. Journal of Essential Oil Research, 16(3), 243-245.
  • Clinical and Laboratory Standards Institute (CLSI), (2017). Performance Standards for Antimicrobial Susceptibility Testing; 27th Informational Supplement. CLSI/NCCLS, 27th ed.; Clinical and Laboratory Standards Institute: Wayne, PA, USA.
  • Davis, P.H., Mill R.R. and Tan, K., (1988). Flora of Turkey and the East Aegean Islands. Edinburgh University Press. Edinburgh, UK.
  • Djihane, B., Wafa, N., Elkhamssa, S., Pedro, D.H.J., Maria, A.E., and Mihoub, Z.M., (2017). Chemical constituents of Helichrysum italicum (Roth) G. Don essential oil and their antimicrobial activity against Gram-positive and Gram-negative bacteria, filamentous fungi and Candida albicans. Saudi Pharmaceutical Journal, 25, 780-787.
  • Ebrahimzadeh, M.A., and Tavassoli, A., (2015). Antioxidant properties of Helichrysum pseudoplicatum Nab. Pharmaceutical and Biomedical Research, 1(1), 37.
  • Ebrahimzadeh, M.A., Nabavi, S.F., Nabavi, S.M., and Eslami, B., (2010). Antihemolytic and antioxidant activities of Allium paradoxum. Central European Journal of Biology, 5, 338-345.
  • El-Olemy, M.M., Al-Rehaily, A.J., Albishi, O.A., Mossa, J.S., Demirci B., and Başer, K.H.C., (2005). Composition of the Essential Oil of Helichrysum forsskahlii (Gmel) Hilliard et Burt. Journal of Essential Oil Research, 17(1), 112-116.
  • Furlan, V., and Bren, U., (2023). Helichrysum italicum: From extraction, distillation, and encapsulation techniques to beneficial health effects. Foods, 12(4), 802.
  • Giovanelli, S., De Leo, M., Cervelli, C., Ruffoni, B., Ciccarelli, D., and Pistelli, L., (2018). Essential oil composition and volatile profile of seven Helichrysum species grown in Italy. Chemistry and Biodiversity, 15, e1700545.
  • Giuliani, C., Lazzaro, L., Calamassi, R., Calamai, L., Romoli, R., Fico, G., Foggi, B., and Lippi, M.M., (2016). A volatolomic approach for studying plant variability: the case of selected Helichrysum species (Asteraceae). Phytochemistry, 130, 128-143.
  • González, A.M., Tracanna, M.I., Amani, S.M., Schuff, C., Poch, M.J., Bach, H., and Can, C., (2012). Chemical composition, antimicrobial and antioxidant properties of the volatile oil and methanol extract of Xenophyllum poposum. Natural Product Communications, 7(12), 1663-1666.
  • Güner, A., S. Aslan, T. Ekim, M. Vural ve M. T. Babaç, 2012. Türkiye Bitkileri Listesi (Damarlı Bitkiler). Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını, İstanbul.
  • Javidnia, K., Miri, R., Soltani M., and Khosravi, A.R., (2009). Essential oil composition of two Iranian endemic Helichrysum Miller. species (H. leucocephalum Boiss. and H. artemisioides Boiss. et Hausskn.). Journal of Essential Oil Research, 21(1), 54-56.
  • Jokić, S., Rajić, M., Bilić, B., and Molnar, M., (2016). Supercritical extraction of scopoletin from Helichrysum italicum (Roth) G. Don flowers. Phytochemical Analysis, 27, 290-295.
  • Judzentiene, A., and Butkiene, R., (2006). Chemical composition of the essential oils of wild Helichrysum arenarium (L.) with differently colored inflorescences from Eastern Lithuania. Journal of Essential Oil Research, 18(1), 80-83.
  • Judžentienė, A., Charkova, T., and Misiūnas, A., (2019). Chemical composition of the essential oils from Helichrysum arenarium (L.) plants growing in Lithuanian forests. Journal of Essential Oil Research, 31(4), 305-311.
  • Kladar, N.V., Anačkov, G.T., Rat, M.M., Srđenović, B.U., Grujić, N.N., Šefer, E.L., and Božin, B.N., (2015). Biochemical characterization of Helichrysum italicum (Roth) G.Don subsp. italicum (Asteraceae) from Montenegro: phytochemical screening, chemotaxonomy, and antioxidant properties. Chemistry and Biodiversity, 12(3), 419-31.
  • Kürkçüoğlu, M., Ağalar, H.G., Aksoy A., and Başer, K.H.C., (2019). Composition of the essential oils of two endemic Helichrysum species in Turkey. Records of Natural Products, 13(3), 236-242.
  • Kurti, F., Giorgi, A., Beretta, G., Mustafa, B., Gelmini, F., Testa, C., Angioletti, S., Giupponi, L., Zilio, E., Pentimalli, D., and Hajdari, A., (2019). Chemical composition, antioxidant and antimicrobial activities of essential oils of different Pinus species from Kosovo. Journal of Essential Oil Research, 31(4), 263-275.
  • Lourens, A.C.U., Reddy, D., Baser, K.H.C., Viljoen, A.M., and Van Vuuren, S.F., (2004). In vitro biological activity and essential oil composition of four indigenous South African Helichrysum Species. Journal of Ethnopharmacology, 95, 253-58.
  • Lourens, A.C.U., Viljoen, A.M., and van Heerden, F.R., (2008). South African Helichrysum species: A review of the traditional uses, biological activity and phytochemistry. Journal of Ethnopharmacology, 119(3), 630¬¬-652.
  • Ornano, L., Venditti, A., Sanna, C., Ballero, M., Maggi, F., Lupidi, G., Bramucci, M., Quassinti, L., and Bianco, A.C., (2015). Chemical composition and biological activity of the essential oil from Helichrysum microphyllum Cambess. ssp. tyrrhenicum Bacch., Brulloe Giusso growing in La Maddalena Archipelago. Sardinia, Journal of Oleo Science, 64(1), 19-26.
  • Özcan, K., and Acet, T., (2018b). Antimicrobial and antioxidant screening, synergy studies of Helichrysum chionophilum extracts against to resistant microbial strains. Fresenius Environmental Bulletin. 27(7), 5045-5052.
  • Özcan, K., and Acet, T., (2022). Stachys macrantha (K.Koch) Stearn’ın biyolojik aktivitesinin belirlenmesi. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 11(1), 156-163.
  • Öztürk, B., Özek, G., Özek, T., and Baser, K.H.C., (2014). Chemical Diversity in Volatiles of Helichrysum plicatum DC. Subspecies in Turkey. Records of Natural Products, 8(4), 373-384.
  • Ralijerson, L.B., Rabehaja, D.J.R., Rajaonarison, J.F., Urverg, S.R., Hérent, M.F. Mavar-Manga, H., and Tilquin, B., (2005). Comparison between the fresh and dry essential oil of Helichrysum faradifani Scott Elliot from Madagascar. Journal of Essential Oil Research, 17(6), 597-600.
  • Rančić A., Soković, M., Vukojević, J., Simić, A., Marin, P., Duletić-Laušević, S., and Djoković, D., (2005). Chemical composition and antimicrobial activities of essential oils of Myrrhis odorata (L.) Scop, Hypericum perforatum L and Helichrysum arenarium (L.) Moench. Journal of Essential Oil Research, 17(3), 341-345.
  • Rossi, P.G., Berti, L., Panighi, J., Luciani, A., Maury, J., Muselli, A., De Rocca Serra, D., Gonny, M., and Bolla, J.M., (2007). Antibacterial action of essential oils from Corsica. Journal of Essential Oil Research, 19, 176-182.
  • Roussis, V., Tsoukatou, M., Chinou L.B., and Harvala, C., (2002). Composition and antibacterial activity of the essential oils of two Helichrysum stoechas varieties growing in the Island of Crete. Journal of Essential Oil Research, 14(6), 459-461.
  • Süzgeç-Selçuk, S., and Birteksöz, A.S., (2011). Flavonoids of Helichrysum chasmolycicum and its antioxidant and antimicrobial activities. South African Journal of Botany, 77(1), 170-174.
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Details

Primary Language English
Subjects Structural Biology
Journal Section Articles
Authors

Tuba Acet 0000-0002-0981-9413

Kadriye Özcan 0000-0002-4913-6035

Early Pub Date June 15, 2023
Publication Date June 15, 2023
Published in Issue Year 2023 Volume: 13 Issue: 2

Cite

APA Acet, T., & Özcan, K. (2023). Antioxidant and antimicrobial activities of the essential oil of Helichrysum chionophilum: an endemic plant of Türkiye. Karadeniz Fen Bilimleri Dergisi, 13(2), 680-689. https://doi.org/10.31466/kfbd.1271087

Cited By

Alternatif Tıpta Kullanılan Helichrysum armenium Türünün (Altınotu) Fenolik İçerik ve Antioksidan Özellikleri
Türk Tarım ve Doğa Bilimleri Dergisi
https://doi.org/10.30910/turkjans.1355478
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