Research Article
BibTex RIS Cite

Etiology and Mortality Investigation in Neonates that Underwent Surgery

Year 2022, Volume: 14 Issue: 1, 99 - 103, 14.03.2022
https://doi.org/10.18521/ktd.1024822

Abstract

Objective
We aimed to examine the demographic characteristics, etiology and postoperative mortality rates of neonates operated on in our hospital.
Methods
The records of neonates who were operated in our tertiary care level university hospital between 2013 and 2019 were reviewed retrospectively. Patients with a diagnosis requiring surgical procedure, age (days), gender, anatomical region where the surgical procedure was performed, length of hospital stay and mortality rates were investigated.
Results
329 neonates were included in the study of which 213 (64.75%) were male and 116 (35.25%) were female. Gastrointestinal system surgery was performed in 214 patients (65.04%), respiratory system surgery in 95 (28.87%) patients and urogenital system surgery in 17 (5.16%) patients. The mortality rate of 156 patients that were followed up in our neonatal unit in the postoperative period was 16.6%. The mortality rate of female babies (21.3%) was higher than that of male babies (13%). Considering the mortality rates of the patients according to the surgical areas, the highest mortality rate was found in respiratory system surgery (38.46%) which was trailed by gastrointestinal system surgery (12.28%) and genitourinary system surgery (7.69%), respectively.
Conclusions
Despite advances in neonatal care and surgical techniques, immaturity and congenital anomalies still have an important place among the most common causes of death in infants. In particular, the detection of organ dysfunctions due to congenital anomalies which are considered among the preventable causes of death in infants, efforts to correct them will be beneficial to a certain extent in reducing the mortality rates of neonates.

References

  • 1. Korkmaz A, Akçören Z, Alanay Y, Özyüncü Ö, Yiğit Ş, Deren Ö ve ark. Hacettepe Üniversitesi Hastanesi 2001-2006 dönemi perinatal mortalite analizi. Çocuk Sağlığı ve Hastalıkları Dergisi 2010; 53: 175-88.
  • 2. Linhart Y, Bashiri A, Maymon E, Shoham-Vardi I, Furman B, Vardi H, et al. Congenital anomalies are an independent risk factor for neonatal morbidity and perinatal mortality in preterm birth. Eur J Obstet Gynecol Reprod Biol. 2000;90(1):43-9.
  • 3. World Health Organization. Maternal Health and Safe Motherhood Programme. (‎1996)‎. Mother-baby package : implementing safe motherhood in countries : practical guide. World Health Organization. Available from: https://apps.who.int/iris/handle/10665/63268
  • 4. Mathews TJ, Minino AM, Osterman MJ, Strobino DM, Guyer B. Annual summary of vital statistics 2008. Pediatrics 2011; 127(1):146-57.
  • 5. Denney JM, Culhane JF, Goldenberg RL. Prevention of preterm birth. Womens Health (Lond Engl) 2008;4(6):625-38.
  • 6. Liu S, Joseph KS, Wen WS. Trends in fetal and infant deaths caused by congenital anomalies. Semin Perinatol 2002; 26(4): 268-76.
  • 7. Gilboa SM, Salemi JL, Nembhard WN, Fixler DE, Correa A. Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. Circulation 2010; 122(22): 2254-63.
  • 8. Hall NJ, Stanton MP, Kitteringham LJ, Wheeler RA, Griffiths DM, Drewett M, et al. Scope and feasibility of operating on the neonatal intensive care unit: 312 cases in 10 years. Pediatr Surg Int. 2012;28(10):1001-5.
  • 9. Celayir AC, Karatekin G. Çocuk Cerrahisinde Gastrointestinal Kökenli Patolojilerde Yoğun Bakım.Turkiye Klinikleri J Pediatr Surg-Special Topics 2010;3(1):69-77.
  • 10.Başaklar AC. Çocukların Cerrahi ve Ürolojik Hastalıkları. Palme Yayıncılık, Ankara 2006.
  • 11. Taguchi T. Current progress in neonatal surgery. Surg Today. 2008;38(5):379-89.
  • 12.Gangopadhyay AN, Upadhyaya VD, Sharma SP. Neonatalsurgery: a ten year audit from a university hospital. Indian J Pediatr. 2008;75(10):1025-30.
  • 13. Çevik M, Açar A ,Boleken ME. Ameliyat edilen yenidoğanlardaki mortalite: Tek bir merkezdeki 275 vakalık seri. Kocaeli Tıp Dergisi 2012;2:18-22
  • 14. Osifo OD, Ovueni ME, Evbuomvan I. The Prevalence, Patterns, and Causes of Deaths of Surgical Neonates at Two African Referral Pediatric Surgical Centers Annals of Pediatric Surgery 2009;5(3): 194-9.
  • 15. Yi B, Wu L, Liu H, Fang W, Hu Y, Wang Y. Rural-urban differences of neonatal mortality in a poorly developed province of China. BMC Public Health. 2011; 11(1): 477.
  • 16. Siddharth V, Gupta SK, Agarwala S, Satpathy S, Goel P. Outcome of Care Provided in Neonatal Surgery Intensive Care Unit of a Public Sector Tertiary Care Teaching Hospital of India. J Indian Assoc Pediatr Surg. 2019;24(4):257-263. doi:10.4103/jiaps.JIAPS_177_18
  • 17. Celayir A, Gence A, Deresoy AF, Yılmazkar S. Cerrahi anomalilerde prenatal tanılama postnatal yaklaşımı değiştirdi mi? Zeynep Kamil Bülteni 2007;38(1). 41-4
  • 18. Bruner JP. In their footsteps: A brief history of maternal-fetal surgery. Clinics in Perinatology. 2003;30:439-47.
  • 19. Deprest JA, Flake AW, Gratacos E, Ville Y, Hecherk, et al. The making of fetal surgery. Prenatal Diagnosis. 2010;30:653-67.
  • 20. Niño DF, Sodhi C, Hackman DJ. Necrotizing enterocolitis: New insights into pathogenesis and mechanisms. Nature Reviews Gastroenterology and Hepatology. 2016;13:590-600.
  • 21. Baeza HC, Cortes GR, Gonzalez MT. Atresia ileoyeyunal. In: Baeza HC, editor. Temas selectos de cirugia neonatal. Mexico: Alfil; 2011: 387-406.
  • 22. Hall NJ, Eaton S, Pierro A. Royal Australasia of Surgeons Guest Lecture. Necrotizing enterocolitis: prevention, treatment, and outcome. J Pediatr Surg. 2013;48(12):2359-67. doi: 10.1016/j.jpedsurg.2013.08.006.
  • 23. Puri A, Lal B, Nangia S. A Pilot Study on Neonatal Surgical Mortality: A Multivariable Analysis of Predictors of Mortality in a Resource-Limited Setting. J Indian Assoc Pediatr Surg. 2019;24(1):36-44. doi:10.4103/jiaps.JIAPS_30_18
  • 24. Boyer TJ, Kritzmire SM. Neonatal Anesthesia. (Updated 2021 Jun 9). In: StatPearls (Internet). Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541030/)
  • 25. Mohta A, Mishra A, Khan NA, et al. Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates. J Indian Assoc Pediatr Surg. 2021;26(5):307-10. doi:10.4103/jiaps.JIAPS_149_20

Ameliyat Olan Yenidoğanlarda Etiyoloji ve Mortalite Araştırması

Year 2022, Volume: 14 Issue: 1, 99 - 103, 14.03.2022
https://doi.org/10.18521/ktd.1024822

Abstract

Amaç
Hastanemizde ameliyat edilen yenidoğanların demografik özelliklerini, etiyolojilerini ve postoperatif mortalite oranlarını incelemeyi amaçladık.
Metod
Üçüncü basamak üniversite hastanemizde 2013-2019 yılları arasında ameliyat edilen yenidoğanların kayıtları geriye dönük olarak incelendi. Cerrahi işlem gerektiren tanısı olan hastaların yaş (gün), cinsiyet, cerrahi işlemin yapıldığı anatomik bölge, hastanede kalış süreleri ve mortalite oranları araştırıldı.
Bulgular
Çalışmaya 213'ü (%64,75) erkek, 116'sı (%35,25) kız olmak üzere 329 yenidoğan alındı. 214 hastada (%65.04) gastrointestinal sistem cerrahisi, 95 (%28,87) hastada solunum sistemi cerrahisi ve 17 (%5.16) hastada ürogenital sistem cerrahisi uygulandı. Yenidoğan ünitemizde postoperatif dönemde takip edilen 156 hastanın mortalite oranı %16,6 idi. Kız bebeklerin ölüm oranı (%21,3) erkek bebeklerden (%13) daha yüksekti. Hastaların cerrahi alanlara göre ölüm oranlarına bakıldığında, en yüksek ölüm oranı solunum sistemi cerrahisinde (%38,46) bulunurken, bunu sırasıyla gastrointestinal sistem cerrahisi (%12,28) ve ürogenital sistem cerrahisi (%7,69) izledi.
Sonuçlar
Yenidoğan bakımı ve cerrahi tekniklerdeki gelişmelere rağmen, immatürite ve konjenital anomaliler, bebeklerde en sık ölüm nedenleri arasında hala önemli bir yer tutmaktadır. Özellikle bebeklerde önlenebilir ölüm nedenleri arasında sayılan doğumsal anomalilere bağlı organ işlev bozukluklarının saptanması, düzeltilmesine yönelik çabalar yenidoğan bebek ölüm oranlarının azaltılmasında bir ölçüde faydalı olacaktır.

References

  • 1. Korkmaz A, Akçören Z, Alanay Y, Özyüncü Ö, Yiğit Ş, Deren Ö ve ark. Hacettepe Üniversitesi Hastanesi 2001-2006 dönemi perinatal mortalite analizi. Çocuk Sağlığı ve Hastalıkları Dergisi 2010; 53: 175-88.
  • 2. Linhart Y, Bashiri A, Maymon E, Shoham-Vardi I, Furman B, Vardi H, et al. Congenital anomalies are an independent risk factor for neonatal morbidity and perinatal mortality in preterm birth. Eur J Obstet Gynecol Reprod Biol. 2000;90(1):43-9.
  • 3. World Health Organization. Maternal Health and Safe Motherhood Programme. (‎1996)‎. Mother-baby package : implementing safe motherhood in countries : practical guide. World Health Organization. Available from: https://apps.who.int/iris/handle/10665/63268
  • 4. Mathews TJ, Minino AM, Osterman MJ, Strobino DM, Guyer B. Annual summary of vital statistics 2008. Pediatrics 2011; 127(1):146-57.
  • 5. Denney JM, Culhane JF, Goldenberg RL. Prevention of preterm birth. Womens Health (Lond Engl) 2008;4(6):625-38.
  • 6. Liu S, Joseph KS, Wen WS. Trends in fetal and infant deaths caused by congenital anomalies. Semin Perinatol 2002; 26(4): 268-76.
  • 7. Gilboa SM, Salemi JL, Nembhard WN, Fixler DE, Correa A. Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. Circulation 2010; 122(22): 2254-63.
  • 8. Hall NJ, Stanton MP, Kitteringham LJ, Wheeler RA, Griffiths DM, Drewett M, et al. Scope and feasibility of operating on the neonatal intensive care unit: 312 cases in 10 years. Pediatr Surg Int. 2012;28(10):1001-5.
  • 9. Celayir AC, Karatekin G. Çocuk Cerrahisinde Gastrointestinal Kökenli Patolojilerde Yoğun Bakım.Turkiye Klinikleri J Pediatr Surg-Special Topics 2010;3(1):69-77.
  • 10.Başaklar AC. Çocukların Cerrahi ve Ürolojik Hastalıkları. Palme Yayıncılık, Ankara 2006.
  • 11. Taguchi T. Current progress in neonatal surgery. Surg Today. 2008;38(5):379-89.
  • 12.Gangopadhyay AN, Upadhyaya VD, Sharma SP. Neonatalsurgery: a ten year audit from a university hospital. Indian J Pediatr. 2008;75(10):1025-30.
  • 13. Çevik M, Açar A ,Boleken ME. Ameliyat edilen yenidoğanlardaki mortalite: Tek bir merkezdeki 275 vakalık seri. Kocaeli Tıp Dergisi 2012;2:18-22
  • 14. Osifo OD, Ovueni ME, Evbuomvan I. The Prevalence, Patterns, and Causes of Deaths of Surgical Neonates at Two African Referral Pediatric Surgical Centers Annals of Pediatric Surgery 2009;5(3): 194-9.
  • 15. Yi B, Wu L, Liu H, Fang W, Hu Y, Wang Y. Rural-urban differences of neonatal mortality in a poorly developed province of China. BMC Public Health. 2011; 11(1): 477.
  • 16. Siddharth V, Gupta SK, Agarwala S, Satpathy S, Goel P. Outcome of Care Provided in Neonatal Surgery Intensive Care Unit of a Public Sector Tertiary Care Teaching Hospital of India. J Indian Assoc Pediatr Surg. 2019;24(4):257-263. doi:10.4103/jiaps.JIAPS_177_18
  • 17. Celayir A, Gence A, Deresoy AF, Yılmazkar S. Cerrahi anomalilerde prenatal tanılama postnatal yaklaşımı değiştirdi mi? Zeynep Kamil Bülteni 2007;38(1). 41-4
  • 18. Bruner JP. In their footsteps: A brief history of maternal-fetal surgery. Clinics in Perinatology. 2003;30:439-47.
  • 19. Deprest JA, Flake AW, Gratacos E, Ville Y, Hecherk, et al. The making of fetal surgery. Prenatal Diagnosis. 2010;30:653-67.
  • 20. Niño DF, Sodhi C, Hackman DJ. Necrotizing enterocolitis: New insights into pathogenesis and mechanisms. Nature Reviews Gastroenterology and Hepatology. 2016;13:590-600.
  • 21. Baeza HC, Cortes GR, Gonzalez MT. Atresia ileoyeyunal. In: Baeza HC, editor. Temas selectos de cirugia neonatal. Mexico: Alfil; 2011: 387-406.
  • 22. Hall NJ, Eaton S, Pierro A. Royal Australasia of Surgeons Guest Lecture. Necrotizing enterocolitis: prevention, treatment, and outcome. J Pediatr Surg. 2013;48(12):2359-67. doi: 10.1016/j.jpedsurg.2013.08.006.
  • 23. Puri A, Lal B, Nangia S. A Pilot Study on Neonatal Surgical Mortality: A Multivariable Analysis of Predictors of Mortality in a Resource-Limited Setting. J Indian Assoc Pediatr Surg. 2019;24(1):36-44. doi:10.4103/jiaps.JIAPS_30_18
  • 24. Boyer TJ, Kritzmire SM. Neonatal Anesthesia. (Updated 2021 Jun 9). In: StatPearls (Internet). Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541030/)
  • 25. Mohta A, Mishra A, Khan NA, et al. Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates. J Indian Assoc Pediatr Surg. 2021;26(5):307-10. doi:10.4103/jiaps.JIAPS_149_20
There are 25 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Evren Büyükfırat 0000-0002-6396-0426

Abit Demir 0000-0002-6400-1841

Mustafa Erman Dörterler 0000-0001-9304-6830

Tansel Günendi 0000-0001-5356-1061

Publication Date March 14, 2022
Acceptance Date February 10, 2022
Published in Issue Year 2022 Volume: 14 Issue: 1

Cite

APA Büyükfırat, E., Demir, A., Dörterler, M. E., Günendi, T. (2022). Etiology and Mortality Investigation in Neonates that Underwent Surgery. Konuralp Medical Journal, 14(1), 99-103. https://doi.org/10.18521/ktd.1024822
AMA Büyükfırat E, Demir A, Dörterler ME, Günendi T. Etiology and Mortality Investigation in Neonates that Underwent Surgery. Konuralp Medical Journal. March 2022;14(1):99-103. doi:10.18521/ktd.1024822
Chicago Büyükfırat, Evren, Abit Demir, Mustafa Erman Dörterler, and Tansel Günendi. “Etiology and Mortality Investigation in Neonates That Underwent Surgery”. Konuralp Medical Journal 14, no. 1 (March 2022): 99-103. https://doi.org/10.18521/ktd.1024822.
EndNote Büyükfırat E, Demir A, Dörterler ME, Günendi T (March 1, 2022) Etiology and Mortality Investigation in Neonates that Underwent Surgery. Konuralp Medical Journal 14 1 99–103.
IEEE E. Büyükfırat, A. Demir, M. E. Dörterler, and T. Günendi, “Etiology and Mortality Investigation in Neonates that Underwent Surgery”, Konuralp Medical Journal, vol. 14, no. 1, pp. 99–103, 2022, doi: 10.18521/ktd.1024822.
ISNAD Büyükfırat, Evren et al. “Etiology and Mortality Investigation in Neonates That Underwent Surgery”. Konuralp Medical Journal 14/1 (March 2022), 99-103. https://doi.org/10.18521/ktd.1024822.
JAMA Büyükfırat E, Demir A, Dörterler ME, Günendi T. Etiology and Mortality Investigation in Neonates that Underwent Surgery. Konuralp Medical Journal. 2022;14:99–103.
MLA Büyükfırat, Evren et al. “Etiology and Mortality Investigation in Neonates That Underwent Surgery”. Konuralp Medical Journal, vol. 14, no. 1, 2022, pp. 99-103, doi:10.18521/ktd.1024822.
Vancouver Büyükfırat E, Demir A, Dörterler ME, Günendi T. Etiology and Mortality Investigation in Neonates that Underwent Surgery. Konuralp Medical Journal. 2022;14(1):99-103.