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Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey

Year 2020, Volume: 9 Issue: Özel Sayı, 23 - 27, 23.10.2020

Pınar Erecevit Sönmez Uğur Çakılcıoğlu

https://doi.org/10.46810/tdfd.732234
Cited By: 4

Abstract

In this study, the antimicrobial effect researched on microorganisms threatening to human health of extract including methanol of Centaurea saligna that is endemic and used for therapy of many diseases. For disk diffusion method, this related extract is highly effective on the gram negative bacteria by its 20.3±0.5 mm inhibition area. Again to relation bacteria, gram positive bacteria are highly effective by 18.3±0.57 mm and 20.3±0.5 mm inhibition area. It has a effect against Candida species and Epidermophyton sp., the superficial skin infections are caused, by 9.6±0.5 mm and 13.6±1.5 mm inhibition area. On the other hand, for findings, this related extract is extremely effective against Trichophyton sp. that is one of dermatophyte fungi by 24.6±1.5 inhibition area. This natural extract shows its antimicrobial effect namely, by minimal inhibition value (MIC): 6.25 µL its lowest inhibition value against development of all the bacteria and dermatophyte fungi.
This plant has a potential to be a natural antimicrobial agent to be used as a medicine for human health and life quality.

Keywords

Centaurea saligna dermatophyte pathogens Bacteria Yeast Antimicrobial effect

References

  • [1] Güvensen NC, Keskin D, Güneş H, Oktay MK, Yıldırım H. Antimicrobial property and antiproliferative activity of Centaurea babylonica (L.) L. on human carcinomas and cervical cancer cell lines. Ann Agric Environ Med. 2019; 26 (2): 290-297.
  • [2] Ozcelik B, Gurbuz I, Karaoglu T, Yesilada E. Antiviral and antimicrobial activities of three sesquiterpene lactones from Centaurea solstitialis L. subsp. solstitialis. Microbiol Res. 2009; 164, 545-552.
  • [3] Khatun S, Parlak KU, Polat R, Cakilcioglu U. The endemic and rare plants of Maden (Elazig) and their uses in traditional medicine. J Herb Med. 2012; 2,3 68-75.
  • [4] Erdogan T, Gonenc T, Cakilcioglu U, Kivcak B. Fatty acid composition of the aerial parts of some Centaurea Species in Elazıg. Turkey Trop J Pharm Res. 2014; 13 (4): 613-616.
  • [5] Uysal I, Çelik S, Sağlam H, Güven K. Antimicrobial and antioxidant activities of Some Species of Centaurea collected from Turkey. Asian J Chem. 2013; 25(2):666-670.
  • [6] Bülent Köse Y, İşcan G, Demirci B, Başer KHC, Çelik S. Antimicrobial activity of the essential oil of Centaurea aladagensis Fitoterapia. 2007; 78: 253-254.
  • [7] Zengin G, Bulut G, Mollica A, Picot-Allain CMN, Mahomoodally MF. In vitro and in silico evaluation of Centaurea saligna (K.Koch) Wagenitz an endemic folk medicinal plant. Comput Biol Chem. 2018; 73: 120-126.
  • [8] Dumlu MU, Gürkan E, Naturforsch Z. A new active compound from Centaurea species. Z Naturforsch C. 2005; 61: 44-46.
  • [9] Koca U, Pesin Süntar I, Keles H, Yesilada E, Küpeli Akkol E. In vivo anti-inflammatory and wound healing activities of Centaurea iberica Trev. ex Spreng. J Ethnopharmacol. 2009; 126 (3): 551-556.
  • [10] Kubacey TM, Haggag EG, El-Toumy SA, Amany AA, El-Ashmawy IM, Youns MM. Biological activity and flavonoids from Centaurea alexanderina leaf extract. J Pharm Res. 2012; 5(6): 3352-3361.
  • [11] Albayrak S, Atasagun B, Aksoy A. Comparison of phenolic components and biological activities of two Centaurea sp. obtained by three extraction techniques. Asian Pac J Trop Med. 2017; 10(6): 599- 606.
  • [12] Baykan Erel S, Demir S, Nalbantsoy A, Ballar P, Khan S, Karaalp C, et al. Cytotoxic, antioxidant, antiinfammatory capacities of five Centaurea L. species and in vivo antiinflammatory evaluation of Centaurea athoa. 10th ISOPS. Ankara; 2012.
  • [13] Zater H, Huet J, Fontaine V, Benayache S, Stevigny C, Duez P, et al. Chemical constituents, cytotoxic, antifungal and antimicrobial properties of Centaurea diluta Ait. sub sp. algeriensis (Coss. & Dur.) Maire. Asian Pac J Trop Med. 2016; 9(6): 554-561.
  • [14] Şen A, Bitiş L, Birteksöz-Tan S, Bulut G. In vitro evaluation of antioxidant and antimicrobial activities of some Centaurea L. species. J Pharm Res. 2013; 1: 42-45.
  • [15] Koukoulitsa E, Skaltsa H, Karioti A, Demetzos C. Bioactive sesquiterpene lactones from Centaurea species and their cytotoxic/cytostatic activity against human cell lines in vitro. Planta Med. 2002; 68(7):649-52.
  • [16] Kilic O. Essential oil compounds of three Centaurea L. taxa from Turkey and their chemotaxonomy. J M Plant Res. 2013; 7(19): 1344-1350.
  • [17] Riham OB, Shaza AEHM, Nahla A. Phenolic profile of Centaurea aegyptiaca L. growing in Egypt and its cytotoxic and antiviral activities. Afr JT radit Complement Altern Med. 2016; 13(6): 135-143.
  • [18] Panagouleas C, Skaltsa H, Lazari D, Skaltsounis A, Sokovic A. Antifungal activity of secondary metabolites of Centaurea raphanina subsp. mixta, growing wild in Greece. Pharm Biol. 2003; 41 (4): 266-270.
  • [19] Barry L, Hainer, MD. Dermatophyte infections. Am Fam Physician. 2003; 67(1):101-109.
  • [20] Davis PH. Flora of Turkey and the Aegean Islands. V: 7, 8, 9. England: Edinburgh Univ. Press;1970-1984-1985.
  • [21] Collins CH, Lyne PM. Microbiological methods. London: Butter worths & Co. (Publishers) Ltd; 1989. p. 410.
  • [22] Güllüce M, Adıgüzel A, Oğütçü H, Şengül M, Karaman I, Şahin F. Antimicrobial effects of Quercus L. extract. Phytother Res. 2004;18 (3): 208-211.
  • [23] Okut N, Yıldırım B, Ekici K, Terzioğlu Ö, Özgökçe F. Identification of chemical composition and antibacterial properties Juniperus oxycedrus L. subsp. oxycedrus leaf essential oil. Y Y U J Agr Sci. 2018; 28(2): 186-191.
  • [24] Keser S, Keser F, Türkoğlu İ, Kaygılı Ö, Tekin S, Demir E, et al. In vitro biological evaluation and phytochemical contents of three Centaurea L. species growing from Eastern Anatolia in Turkey. KSÜ J Agr Nat. 2020; 23 (1): 148-156.
  • [25] Tekeli Y, Zengin G, Aktumsek A, Sezgin M, Torlak E. Antibacterial activities of extracts from twelve Centaurea species from Turkey. Arch Biol Sci Belgrade. 2011; 63 (3): 685-690.
  • [26] Bach SM, Fortuna MA, de Trimarco ARJT, Catalan CAN, Av-Gay Y, Bach H. Antibacterial and cytotoxic activities of the sesquiterpene lactones cnicin and onopordopicrin. Nat Prod Commun. 2011; 6 (2):163-166.
  • [27] Sarker Satyajit D, Nahar L, Gujja S, Begum S, Celik S. Bioactivity of Centaurea persica Boiss. (Asteraceae). Arch Biol Sci 2012; 64 (2):517-523.

Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey

Year 2020, Volume: 9 Issue: Özel Sayı, 23 - 27, 23.10.2020

Pınar Erecevit Sönmez Uğur Çakılcıoğlu

https://doi.org/10.46810/tdfd.732234
Cited By: 4

Abstract

In this study, the antimicrobial effect researched on microorganisms threatening to human health of extract including methanol of Centaurea saligna that is endemic and used for therapy of many diseases. For disk diffusion method, this related extract is highly effective on the gram negative bacteria by its 20.3±0.5 mm inhibition area. Again to relation bacteria, gram positive bacteria are highly effective by 18.3±0.57 mm and 20.3±0.5 mm inhibition area. It has a effect against Candida species and Epidermophyton sp., the superficial skin infections are caused, by 9.6±0.5 mm and 13.6±1.5 mm inhibition area. On the other hand, for findings, this related extract is extremely effective against Trichophyton sp. that is one of dermatophyte fungi by 24.6±1.5 inhibition area. This natural extract shows its antimicrobial effect namely, by minimal inhibition value (MIC): 6.25 µL its lowest inhibition value against development of all the bacteria and dermatophyte fungi. This plant has a potential to be a natural antimicrobial agent to be used as a medicine for human health and life quality.

Keywords

Centaurea saligna Dermatophyte pathogens Bacteria Yeast

References

  • [1] Güvensen NC, Keskin D, Güneş H, Oktay MK, Yıldırım H. Antimicrobial property and antiproliferative activity of Centaurea babylonica (L.) L. on human carcinomas and cervical cancer cell lines. Ann Agric Environ Med. 2019; 26 (2): 290-297.
  • [2] Ozcelik B, Gurbuz I, Karaoglu T, Yesilada E. Antiviral and antimicrobial activities of three sesquiterpene lactones from Centaurea solstitialis L. subsp. solstitialis. Microbiol Res. 2009; 164, 545-552.
  • [3] Khatun S, Parlak KU, Polat R, Cakilcioglu U. The endemic and rare plants of Maden (Elazig) and their uses in traditional medicine. J Herb Med. 2012; 2,3 68-75.
  • [4] Erdogan T, Gonenc T, Cakilcioglu U, Kivcak B. Fatty acid composition of the aerial parts of some Centaurea Species in Elazıg. Turkey Trop J Pharm Res. 2014; 13 (4): 613-616.
  • [5] Uysal I, Çelik S, Sağlam H, Güven K. Antimicrobial and antioxidant activities of Some Species of Centaurea collected from Turkey. Asian J Chem. 2013; 25(2):666-670.
  • [6] Bülent Köse Y, İşcan G, Demirci B, Başer KHC, Çelik S. Antimicrobial activity of the essential oil of Centaurea aladagensis Fitoterapia. 2007; 78: 253-254.
  • [7] Zengin G, Bulut G, Mollica A, Picot-Allain CMN, Mahomoodally MF. In vitro and in silico evaluation of Centaurea saligna (K.Koch) Wagenitz an endemic folk medicinal plant. Comput Biol Chem. 2018; 73: 120-126.
  • [8] Dumlu MU, Gürkan E, Naturforsch Z. A new active compound from Centaurea species. Z Naturforsch C. 2005; 61: 44-46.
  • [9] Koca U, Pesin Süntar I, Keles H, Yesilada E, Küpeli Akkol E. In vivo anti-inflammatory and wound healing activities of Centaurea iberica Trev. ex Spreng. J Ethnopharmacol. 2009; 126 (3): 551-556.
  • [10] Kubacey TM, Haggag EG, El-Toumy SA, Amany AA, El-Ashmawy IM, Youns MM. Biological activity and flavonoids from Centaurea alexanderina leaf extract. J Pharm Res. 2012; 5(6): 3352-3361.
  • [11] Albayrak S, Atasagun B, Aksoy A. Comparison of phenolic components and biological activities of two Centaurea sp. obtained by three extraction techniques. Asian Pac J Trop Med. 2017; 10(6): 599- 606.
  • [12] Baykan Erel S, Demir S, Nalbantsoy A, Ballar P, Khan S, Karaalp C, et al. Cytotoxic, antioxidant, antiinfammatory capacities of five Centaurea L. species and in vivo antiinflammatory evaluation of Centaurea athoa. 10th ISOPS. Ankara; 2012.
  • [13] Zater H, Huet J, Fontaine V, Benayache S, Stevigny C, Duez P, et al. Chemical constituents, cytotoxic, antifungal and antimicrobial properties of Centaurea diluta Ait. sub sp. algeriensis (Coss. & Dur.) Maire. Asian Pac J Trop Med. 2016; 9(6): 554-561.
  • [14] Şen A, Bitiş L, Birteksöz-Tan S, Bulut G. In vitro evaluation of antioxidant and antimicrobial activities of some Centaurea L. species. J Pharm Res. 2013; 1: 42-45.
  • [15] Koukoulitsa E, Skaltsa H, Karioti A, Demetzos C. Bioactive sesquiterpene lactones from Centaurea species and their cytotoxic/cytostatic activity against human cell lines in vitro. Planta Med. 2002; 68(7):649-52.
  • [16] Kilic O. Essential oil compounds of three Centaurea L. taxa from Turkey and their chemotaxonomy. J M Plant Res. 2013; 7(19): 1344-1350.
  • [17] Riham OB, Shaza AEHM, Nahla A. Phenolic profile of Centaurea aegyptiaca L. growing in Egypt and its cytotoxic and antiviral activities. Afr JT radit Complement Altern Med. 2016; 13(6): 135-143.
  • [18] Panagouleas C, Skaltsa H, Lazari D, Skaltsounis A, Sokovic A. Antifungal activity of secondary metabolites of Centaurea raphanina subsp. mixta, growing wild in Greece. Pharm Biol. 2003; 41 (4): 266-270.
  • [19] Barry L, Hainer, MD. Dermatophyte infections. Am Fam Physician. 2003; 67(1):101-109.
  • [20] Davis PH. Flora of Turkey and the Aegean Islands. V: 7, 8, 9. England: Edinburgh Univ. Press;1970-1984-1985.
  • [21] Collins CH, Lyne PM. Microbiological methods. London: Butter worths & Co. (Publishers) Ltd; 1989. p. 410.
  • [22] Güllüce M, Adıgüzel A, Oğütçü H, Şengül M, Karaman I, Şahin F. Antimicrobial effects of Quercus L. extract. Phytother Res. 2004;18 (3): 208-211.
  • [23] Okut N, Yıldırım B, Ekici K, Terzioğlu Ö, Özgökçe F. Identification of chemical composition and antibacterial properties Juniperus oxycedrus L. subsp. oxycedrus leaf essential oil. Y Y U J Agr Sci. 2018; 28(2): 186-191.
  • [24] Keser S, Keser F, Türkoğlu İ, Kaygılı Ö, Tekin S, Demir E, et al. In vitro biological evaluation and phytochemical contents of three Centaurea L. species growing from Eastern Anatolia in Turkey. KSÜ J Agr Nat. 2020; 23 (1): 148-156.
  • [25] Tekeli Y, Zengin G, Aktumsek A, Sezgin M, Torlak E. Antibacterial activities of extracts from twelve Centaurea species from Turkey. Arch Biol Sci Belgrade. 2011; 63 (3): 685-690.
  • [26] Bach SM, Fortuna MA, de Trimarco ARJT, Catalan CAN, Av-Gay Y, Bach H. Antibacterial and cytotoxic activities of the sesquiterpene lactones cnicin and onopordopicrin. Nat Prod Commun. 2011; 6 (2):163-166.
  • [27] Sarker Satyajit D, Nahar L, Gujja S, Begum S, Celik S. Bioactivity of Centaurea persica Boiss. (Asteraceae). Arch Biol Sci 2012; 64 (2):517-523.
There are 27 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Articles
Authors

Pınar Erecevit Sönmez 0000-0003-2389-0694

Uğur Çakılcıoğlu 0000-0002-3627-3604

Publication Date October 23, 2020
Published in Issue Year 2020 Volume: 9 Issue: Özel Sayı

Cite

APA Erecevit Sönmez, P., & Çakılcıoğlu, U. (2020). Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey. Türk Doğa Ve Fen Dergisi, 9(Özel Sayı), 23-27. https://doi.org/10.46810/tdfd.732234
AMA Erecevit Sönmez P, Çakılcıoğlu U. Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey. TJNS. October 2020;9(Özel Sayı):23-27. doi:10.46810/tdfd.732234
Chicago Erecevit Sönmez, Pınar, and Uğur Çakılcıoğlu. “Screening of Antimicrobial Effect Against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea Saligna (C. Koch) Wagenitz from Turkey”. Türk Doğa Ve Fen Dergisi 9, no. Özel Sayı (October 2020): 23-27. https://doi.org/10.46810/tdfd.732234.
EndNote Erecevit Sönmez P, Çakılcıoğlu U (October 1, 2020) Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey. Türk Doğa ve Fen Dergisi 9 Özel Sayı 23–27.
IEEE P. Erecevit Sönmez and U. Çakılcıoğlu, “Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey”, TJNS, vol. 9, no. Özel Sayı, pp. 23–27, 2020, doi: 10.46810/tdfd.732234.
ISNAD Erecevit Sönmez, Pınar - Çakılcıoğlu, Uğur. “Screening of Antimicrobial Effect Against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea Saligna (C. Koch) Wagenitz from Turkey”. Türk Doğa ve Fen Dergisi 9/Özel Sayı (October 2020), 23-27. https://doi.org/10.46810/tdfd.732234.
JAMA Erecevit Sönmez P, Çakılcıoğlu U. Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey. TJNS. 2020;9:23–27.
MLA Erecevit Sönmez, Pınar and Uğur Çakılcıoğlu. “Screening of Antimicrobial Effect Against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea Saligna (C. Koch) Wagenitz from Turkey”. Türk Doğa Ve Fen Dergisi, vol. 9, no. Özel Sayı, 2020, pp. 23-27, doi:10.46810/tdfd.732234.
Vancouver Erecevit Sönmez P, Çakılcıoğlu U. Screening of Antimicrobial Effect against Microorganisms Threatening to Human Health of the Endemic Plant; Centaurea saligna (C. Koch) Wagenitz from Turkey. TJNS. 2020;9(Özel Sayı):23-7.

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