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Investigation of The Effect of Thymbra spicata L. var. spicata Plant Extracts on DNA Protective Activities and Stenotrophomonas maltophilia

Year 2020, Volume: 1 Issue: 2, 28 - 34, 22.04.2020

Abstract

In alternative treatments in the world, botanical extracts are used for treatment in many diseases. The fact that our country has different climatic and ecological conditions, Flora contains many plant species and diversity and therefore there are many plant species consumed for medical purposes in our country. Most of these plants have antimicrobial effects and have been reported both in Turkey and abroad. Studies have shown that some plant extracts and essential oils that naturally grow in the soil show antifungal activity against fungi as well as bacterial activity. Antimicrobial effects of these extracts against Stenotrophomonas maltophilia bacteria and DNA protective activity were studied. The antimicrobial activity was tested Disk Diffusion method. DNA protecting activity was studied using H2O2 and UV-C using pBR322 plasmid DNA. Water and Methanol extracts did show antimicrobial activity on bacteria. On the other hand They showed a high activity in terms of DNA protective activity.

References

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  • 3. Berber, İ., Avşar, C., Çine, N., Bozkurt, N. ve Elmas E. (2013). Determination Of Antibacterial and Antifungal Activities of Methanolic Extracts of Some PlantsGrowing in Sinop Karaelmas'' Science and Engineering Journal 3(1), 10-16.
  • 4. Toroğlu, S., Dığrak, M., Kocabaş, Y.Z. (2005). Çay veya Baharat Olarak Tüketilen Teucrium polium L., Thymbra spicata L. var. spicata, Ocimum basilicum L. ve Foeniculum vulgare Miller’ in Uçucu Yağlarının In-Vitro Antimikrobiyal Aktivitesi ve Bazı Antibiyotiklerle Etkileşimleri KSÜ. Fen ve Mühendislik Dergisi, 8(2), 36-42.
  • 5. Njume, C., Afolayan, AJ. ve Ndip, R.N. (2009). An Overview of Antimicrobial Resistance and The Future of Medicinal Plants in The Treatment of Helicobacterpylori Infections'', Afr. J. Pharm. Pharmacol. 3, 685-699.
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  • 7. Bayram, E., Kırıcı, E., Tansi, S., Yılmaz, G., Arabacı, O., Kızıl, S., Telci, İ. (2010). Tıbbi ve Aromatik Bitkiler Üretiminin Arttırılması Olanakları, Ziraat Mühendisliği VII. Teknik Kongresi, Bildiriler Kitabı-1, 11-15 Ocak Ankara, 437-457,
  • 8. Vonderbank, H. (1949). Ergebnisse der Chemotherapieder Tuberculose, Pharmazie, 4:198-207.
  • 9. Dığrak, M., İlçim, A., Alma, M.H. (1999). Antimicrobialactivities of severalparts of Pinus brutia, Juniperusoxycedrus, Abies cilicia, Cedrus libani and Pinusnigra. Phytotherapy Research, 13: 584-587.
  • 10. Dorman, H.J.D., Deans, S.G. (2000). Antimikrobiyal agents fromm plants:antibacterial activity of plant volatile oils. Journal of Appliedd Mizrobiology 88:308-316.
  • 11. Akgül, A. (1993). Baharat Bilimi ve Teknolojisi. Gıda Teknolojisi Derneği Yayın 15, Ankara, s.451
  • 12. Abascal, K., Yarnell, E. (2002). Herbs and Drug Resistance. Potential of Botanical in Drug-Resistant Microbes. Alternative & Complementary Therapies, 1, 237-241.
  • 13. Tepe, B., Degerli, S., Arslan, S., Malatyali, E., Sarikurkcu, C. (2011). Determination of chemical profile, antioxidant, DNA damage protection andantiamoebic activities of Teucrium polium and Stachys iberica. Fitoterapia,82(2): 237–246.
  • 14. Cragg, G.M., Body, M.R., Cardellina, J.H., Grever, M.R., Schepartz, S.S. and Spader, K.M. (1993). The role of plants in the drug discovery program of the US manuipulation.eln.,International Crop Science 1 Maddison, USA'', Crop Science Society of America, 179-196.
  • 15. Nakipoğlu, M., Otan, H. (1992). Tıbbi Bitkilerin Flavonitleri. Anadolu, J. of AARI 4(1), s. 70-93
  • 16. Nigg, H.N. ve Seigler, D. (1992). Phytochemical resources form medicine andagriculture, New York, Plenum Pres. 76-363.
  • 17. Faydaoğlu, E., Sürücüoğlu, M. (2013). Tıbbi Ve Aromatik Bitkilerin Antimikrobiyal, Antioksidan Aktiviteleri Ve Kullanım Olanakları. Fen Bilimleri Enstitüsü Dergisi Cilt-Sayı: 6-2 Yıl: 2013 233-265
  • 18. Kızıl, S., Tonçer, Ö. (2003). Değisik Azot Dozlarının Floradan Toplanan Karabas Kekik (Thymbra Spicata Var. Spicata L.)’İn Bazı Agronomik Ve Kalite Özellikleri Üzerine Etkisi. Anadolu, J. of AARI 13(1), 132 – 141
  • 19. Downs, C. A., Kramarsky-Winter, E., Segal, R., Fauth, J., Knutson, S., Bronstein, O., Frederic R.C., Jeger, R., Lichtenfeld, Y., Woodley, C.M., Pennington, P., Cadenas, K., Kushmaro, A., Loya, A. (2015). Toxicopathological Effects of the Sunscreen UV Filter, Oxybenzone (Benzophenone-3), on Coral Planulae and Cultured Primary Cells and Its Environmental Contamination in Hawaii and the U.S. Virgin Islands, Arch Environ Contam Toxicol, 70: 265–288.
  • 20. Zachary, R. Hopkins, Snowberger, S., Blaney, L. (2017). Ozonation of the oxybenzone, octinoxate, and octocrylene UV-filters: Reaction kinetics, absorbance characteristics, and transformationproducts, Journal of Hazardous Materials, 338 23–32.

Zahter (Thymbra spicata L. var. spicata) Bitki Özütlerinin DNA Koruyucu Aktivitelerinin ve Stenotrophomonas maltophilia Üzerine Antimikrobiyal Etkisinin Araştırılması

Year 2020, Volume: 1 Issue: 2, 28 - 34, 22.04.2020

Abstract

References

  • 1. Barış, D., Kızıl, M., Çeken, B., Yavuz, M. ve Aytekin, Ç. (2005). Bazı Hypericum Türlerinin in-vitro Antimikrobiyal ve Antioksidan Aktivitelerinin Araştırılması, XIX. Ulusal Kimya Kongresi, Kuşadası.
  • 2. Baytop, T. (1999). Therapy with Medicinal Plants in Turkey (past and Present), 2nd ed. Nobel Tıp Kitabevi, Istanbul, Turkey.
  • 3. Berber, İ., Avşar, C., Çine, N., Bozkurt, N. ve Elmas E. (2013). Determination Of Antibacterial and Antifungal Activities of Methanolic Extracts of Some PlantsGrowing in Sinop Karaelmas'' Science and Engineering Journal 3(1), 10-16.
  • 4. Toroğlu, S., Dığrak, M., Kocabaş, Y.Z. (2005). Çay veya Baharat Olarak Tüketilen Teucrium polium L., Thymbra spicata L. var. spicata, Ocimum basilicum L. ve Foeniculum vulgare Miller’ in Uçucu Yağlarının In-Vitro Antimikrobiyal Aktivitesi ve Bazı Antibiyotiklerle Etkileşimleri KSÜ. Fen ve Mühendislik Dergisi, 8(2), 36-42.
  • 5. Njume, C., Afolayan, AJ. ve Ndip, R.N. (2009). An Overview of Antimicrobial Resistance and The Future of Medicinal Plants in The Treatment of Helicobacterpylori Infections'', Afr. J. Pharm. Pharmacol. 3, 685-699.
  • 6. Şahin, G. (2007). Türkiye’ den Toplanan Bazı Paeonia Türlerinin Antibakteriyel Etkisi, Yüksek Lisans Tezi, Ankara Üniversitesi Fen Bilimleri Enstitüsü, Ankara
  • 7. Bayram, E., Kırıcı, E., Tansi, S., Yılmaz, G., Arabacı, O., Kızıl, S., Telci, İ. (2010). Tıbbi ve Aromatik Bitkiler Üretiminin Arttırılması Olanakları, Ziraat Mühendisliği VII. Teknik Kongresi, Bildiriler Kitabı-1, 11-15 Ocak Ankara, 437-457,
  • 8. Vonderbank, H. (1949). Ergebnisse der Chemotherapieder Tuberculose, Pharmazie, 4:198-207.
  • 9. Dığrak, M., İlçim, A., Alma, M.H. (1999). Antimicrobialactivities of severalparts of Pinus brutia, Juniperusoxycedrus, Abies cilicia, Cedrus libani and Pinusnigra. Phytotherapy Research, 13: 584-587.
  • 10. Dorman, H.J.D., Deans, S.G. (2000). Antimikrobiyal agents fromm plants:antibacterial activity of plant volatile oils. Journal of Appliedd Mizrobiology 88:308-316.
  • 11. Akgül, A. (1993). Baharat Bilimi ve Teknolojisi. Gıda Teknolojisi Derneği Yayın 15, Ankara, s.451
  • 12. Abascal, K., Yarnell, E. (2002). Herbs and Drug Resistance. Potential of Botanical in Drug-Resistant Microbes. Alternative & Complementary Therapies, 1, 237-241.
  • 13. Tepe, B., Degerli, S., Arslan, S., Malatyali, E., Sarikurkcu, C. (2011). Determination of chemical profile, antioxidant, DNA damage protection andantiamoebic activities of Teucrium polium and Stachys iberica. Fitoterapia,82(2): 237–246.
  • 14. Cragg, G.M., Body, M.R., Cardellina, J.H., Grever, M.R., Schepartz, S.S. and Spader, K.M. (1993). The role of plants in the drug discovery program of the US manuipulation.eln.,International Crop Science 1 Maddison, USA'', Crop Science Society of America, 179-196.
  • 15. Nakipoğlu, M., Otan, H. (1992). Tıbbi Bitkilerin Flavonitleri. Anadolu, J. of AARI 4(1), s. 70-93
  • 16. Nigg, H.N. ve Seigler, D. (1992). Phytochemical resources form medicine andagriculture, New York, Plenum Pres. 76-363.
  • 17. Faydaoğlu, E., Sürücüoğlu, M. (2013). Tıbbi Ve Aromatik Bitkilerin Antimikrobiyal, Antioksidan Aktiviteleri Ve Kullanım Olanakları. Fen Bilimleri Enstitüsü Dergisi Cilt-Sayı: 6-2 Yıl: 2013 233-265
  • 18. Kızıl, S., Tonçer, Ö. (2003). Değisik Azot Dozlarının Floradan Toplanan Karabas Kekik (Thymbra Spicata Var. Spicata L.)’İn Bazı Agronomik Ve Kalite Özellikleri Üzerine Etkisi. Anadolu, J. of AARI 13(1), 132 – 141
  • 19. Downs, C. A., Kramarsky-Winter, E., Segal, R., Fauth, J., Knutson, S., Bronstein, O., Frederic R.C., Jeger, R., Lichtenfeld, Y., Woodley, C.M., Pennington, P., Cadenas, K., Kushmaro, A., Loya, A. (2015). Toxicopathological Effects of the Sunscreen UV Filter, Oxybenzone (Benzophenone-3), on Coral Planulae and Cultured Primary Cells and Its Environmental Contamination in Hawaii and the U.S. Virgin Islands, Arch Environ Contam Toxicol, 70: 265–288.
  • 20. Zachary, R. Hopkins, Snowberger, S., Blaney, L. (2017). Ozonation of the oxybenzone, octinoxate, and octocrylene UV-filters: Reaction kinetics, absorbance characteristics, and transformationproducts, Journal of Hazardous Materials, 338 23–32.
There are 20 citations in total.

Details

Primary Language Turkish
Subjects Structural Biology
Journal Section Research Articles
Authors

Mahdı Hussaın Joma This is me

Mesut Çay

İbrahim Halil Kılıç This is me

Mehmet Özaslan

Publication Date April 22, 2020
Submission Date April 13, 2020
Published in Issue Year 2020 Volume: 1 Issue: 2

Cite

EndNote Joma MH, Çay M, Kılıç İH, Özaslan M (April 1, 2020) Zahter (Thymbra spicata L. var. spicata) Bitki Özütlerinin DNA Koruyucu Aktivitelerinin ve Stenotrophomonas maltophilia Üzerine Antimikrobiyal Etkisinin Araştırılması. Zeugma Biological Science 1 2 28–34.