BibTex RIS Kaynak Göster

Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer

Yıl 2014, Cilt: 17 Sayı: 1, 32 - 38, 19.11.2014

Karwan Mahmood Emel Büyükünal Bal

https://doi.org/10.18016/ksujns.71116
Cited By: 1

Öz

Abstract: Recently, the main point of discussion is being undertaken whether the resistance of bacteria and plasmids could have been transmitted to humans from animals. Using antimicrobials in livestock production was previously shown to be followed by the occurrence of the resistant bacteria in the treated animals as well as in humans (caretakers, their family members etc.). Evidences exist that the transmission of resistance might have taken place from animals to humans. Many of these evidences were not direct and were based on the similarities between the resistance profiles of bacteria (among others indicatory E. coli) isolated from animals (poultry, pigs, cattle) and from humans having contact with these animals (farm workers, animal caretakers, their family members). Direct evidences have been based on the molecular methods allowing the detection of either clonally related, resistant zoonotic bacteria in humans and animals or related to resistance of plasmids isolated from humans and animals.

Key words: Enterobacteriaceae, β-lactamase, E. coli, CTX-M

 

Antibiyotik Dirençli Enterobacteriaceae’lerin Hayvan ve İnsan Sindirim Sistemi Arasında in vivo Plazmit Transferinden Kaynaklı Geçişi

Özet: Esas tartışma konusu olan nokta, bakteri ve plazmit kaynaklı bakteri direncinin hayvanlardan insanlara nasıl geçebileceğidir. Antibiyotiklerin çiftlik hayvanlarında kullanımı daha önceleri dirençli bakterilerin tedavi görmüş hayvanlarda ve insanlarda varlığını göstermiştir (hayvan bakıcıları ve çiftlik çalışanları). Direncin geçişinin hayvanlardan insanlara doğru olabileceği şeklinde kanıtlar bulunmaktadır. Bu kanıtların çoğu, direkt olmamakla birlikte hayvanlardan (çiftlik hayvanları) ve bunlarla temas halindeki insanlardan (hayvan bakıcıları ve çiftlik çalışanları) izole edilen bakteriler arasındaki direnç profillerinin benzerliklerine dayanmaktadır. Direkt kanıtlar, birbirleriyle klonal ilişkili insan ve hayvan kaynaklı dirençli zoonotik bakterilerin veya yine bunlardaki dirençle ilgili plazmitlerin moleküler metotlara dayalı olarak saptanması ile olmuştur.

Anahtar kelimeler: Enterobacteriaceae, β-laktamaz, E. coli, CTX-M

Anahtar Kelimeler

Enterobacteriaceae β-lactamase E. coli CTX-M

Kaynakça

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  • Alhaj, N., Mariana, N.S., Raha, A.R., Ishak, Z., 2007. Prevalence of antibiotic resistance among Escherichia coli from different sources in Malaysia. International J. Poult. Sci, 6(4): 293-297.
  • Allen, K. J., Poppe, C., 2002. Occurrence and characterization of resistance to extended- spectrum cephalosporins mediated by beta-lactamase CMY-2 in Salmonella isolated from food-producing animals in Canada. Can J Vet Res, 66: 137-144.
  • Andersson, D.I., 2003. Persistence of antibiotic resistant bacteria. Curr. Opin. Microbiol, 6(5): 452-456.
  • Ardiles-Villegas, K., Gonzalez-Acuna, D., Waldenstrom, J., Olsen, B., Hernandez, J., 2011. Antibiotic resistance patterns in fecal bacteria isolated from Christmas shearwater (Puffinus nativitatis) and masked booby (Sula dactylatra) at remote Easter Island. Avian Dis. 55:486-489.
  • Bahl, M. I., Burmolle, M., Meisner, A., Hansen, L. H., Sorensen, S. J., 2009. All IncP-1 plasmid subgroups, including the novel epsilon subgroup, are prevalent in the influent of a Danish wastewater treatment plant. Plasmid, 62:134-139.
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Yıl 2014, Cilt: 17 Sayı: 1, 32 - 38, 19.11.2014

Karwan Mahmood Emel Büyükünal Bal

https://doi.org/10.18016/ksujns.71116
Cited By: 1

Öz

Esas tartışma konusu olan nokta, bakteri ve plazmit kaynaklı bakteri direncinin hayvanlardan insanlara nasılgeçebileceğidir. Antibiyotiklerin çiftlik hayvanlarında kullanımı daha önceleri dirençli bakterilerin tedavi görmüşhayvanlarda ve insanlarda varlığını göstermiştir (hayvan bakıcıları ve çiftlik çalışanları). Direncin geçişininhayvanlardan insanlara doğru olabileceği şeklinde kanıtlar bulunmaktadır. Bu kanıtların çoğu, direkt olmamakla birliktehayvanlardan (çiftlik hayvanları) ve bunlarla temas halindeki insanlardan (hayvan bakıcıları ve çiftlik çalışanları) izoleedilen bakteriler arasındaki direnç profillerinin benzerliklerine dayanmaktadır. Direkt kanıtlar, birbirleriyle klonal ilişkiliinsan ve hayvan kaynaklı dirençli zoonotik bakterilerin veya yine bunlardaki dirençle ilgili plazmitlerin molekülermetotlara dayalı olarak saptanması ile olmuştur.

Anahtar Kelimeler

Enterobacteriaceae β-laktamaz E. coli CTX-M

Kaynakça

  • Abbott, J. W., Hall-Robinson, E., McDermott, P. F., 2008. Antimicrobial resistance in Salmonella enterica Serovar Heidelberg isolates from retail meats, including poultry, from 2002 to 2006. Appl. Environ. Microb. 74: 6656-6662.
  • Alhaj, N., Mariana, N.S., Raha, A.R., Ishak, Z., 2007. Prevalence of antibiotic resistance among Escherichia coli from different sources in Malaysia. International J. Poult. Sci, 6(4): 293-297.
  • Allen, K. J., Poppe, C., 2002. Occurrence and characterization of resistance to extended- spectrum cephalosporins mediated by beta-lactamase CMY-2 in Salmonella isolated from food-producing animals in Canada. Can J Vet Res, 66: 137-144.
  • Andersson, D.I., 2003. Persistence of antibiotic resistant bacteria. Curr. Opin. Microbiol, 6(5): 452-456.
  • Ardiles-Villegas, K., Gonzalez-Acuna, D., Waldenstrom, J., Olsen, B., Hernandez, J., 2011. Antibiotic resistance patterns in fecal bacteria isolated from Christmas shearwater (Puffinus nativitatis) and masked booby (Sula dactylatra) at remote Easter Island. Avian Dis. 55:486-489.
  • Bahl, M. I., Burmolle, M., Meisner, A., Hansen, L. H., Sorensen, S. J., 2009. All IncP-1 plasmid subgroups, including the novel epsilon subgroup, are prevalent in the influent of a Danish wastewater treatment plant. Plasmid, 62:134-139.
  • Balis, E., Vatopoulos, A.C., Opoulou, M.K., Mainas, E., Hatzoudis, G., Kontogianni, V., Malamou-Lada, H., Kitsou-Kiriakopoulou, S., Kalapothaki, V., 1996. Indications of in vitro transfer of an epidemic R plasmid from Salmonella enteritidis to Escherichia coli of the normal human gut flora. J. Clinic. Microb, 34(4): 977-979.
  • Bertrand, S., Weill, F. X., Cloeckaert, A., Vrints, M., Mairiaux, E., Praud, K., Dierick, K., Wildemauve, C., Godard, C., Butaye, P., Imberechts, H., Grimont, P. A., Collard, J. M., 2006. Clonal emergence of extended-spectrum beta-lactamase (CTX-M-2)producing Salmonella enterica serovar Virchow isolates with reduced susceptibilities to ciprofloxacin among poultry and humans in Belgium and France (2000 to 2003). J. Clin. Microb, 44: 2897-903.
  • Bettelheim, K., Thomas, G., 1997. Escherichia coli Antibiotic Resistotypes. http://ecoli.bham.ac.uk/path/antir.html
  • Boehme, S., Werner, G., Klare, I., Reissbrodt, R., Witte, W., 2004. Occurrence of antibiotic resistant enterobacteria in agricultural foodstuffs. Mol. Nutr. Food Res. 48:522-531.
  • Boerlin, P., Travis, R., Gyles, C.L., Reid-Smith,R., Lim, N.J.H., Nicholson, V., McEwen, S.A., Friendship, R., Archambault, M., 2005. Antimicrobial resistance and virulence genes of Escherichia coli isolates from swine in Ontario. Appl. Environ. Microbiol, 71(11): 6753-6761.
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  • Hasman, H., Mevius, D., Veldman, K., Olesen, I., Aarestrup, F. M., 2005. β-lactamases amoung extended-spectrum β-lactamase (ESBL)-resistant Salmonella from poultry, poultry products and human patients in the Netherlands. J Antimicrob Chemother, 56: 115 121.
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  • Jouini, A., Vinué, L., Slama, K. B., Saénz, Y., Klibi, N., Hammami, S., Boudabous, A., Torres, C., 2007. Characterization of CTX-M and SHV extendedspectrum β-lactamases and associated resistance genes in Escherichia coli strains of food samples in Tunesia. J Antimicrob Chemother 60: 1137-1141.
  • Khan, A. A., Nawaz, M. S., Summage, W. C., Khan, S. A., Lin, J., 2005. Isolation and molecular characterization of fluoroquinolone-resistant Escherichia coli from poultry litter. Poult. Sci. 84:61
  • Kiratisin, P., Apisarnthanarak, A., Laesripa, C., Saifon, P., 200 Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. Antimicrob Agents Chemother, 52: 2818-2824.
  • Kojima, A., Ishii, Y., Ishihara, K., Esaki, H., Asai, T., Oda, C., Tamura, Y., Takahashi, T., Yamaguchio, K., 200 Extended-spectrum-β-lactamase-producing Escherichia coli strains isolated from farm animals from 1999 to 2002: report from the Japanese veterinary antimicrobial resistance monitoring program. Antimicrob Agents Chemother, 49: 353335
  • Kruger, T., Szabo, D., Keddy, K. H., Deeley, K., Marsh, J. W., Hujer, A. M., Bonomo, R. A., Paterson, D. L., 200 Infections with nontyphoidal Salmonella species producing TEM-63 or a novel TEM enzyme, TEM-131, in South Africa. Antimicrob Agents Chemother, 48: 4263-4270.
  • Leverstein-van Hall, M. A., Dierikx, C. M., Cohen, S. J., Voets, G. M., Van den Munckhof, M. P., EssenZandbergen, A., Platteel, T., Fluit, A. C., SandeBruinsma, N., Scharinga, J., Bonten, M. J., Mevius, D. J., 2011. Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains. Clin. Microbiol. Infect. 17:873-880.
  • Levy, S. B., FitzGerald, G. B., Macone, A. B., 1976. Spread of antibiotic-resistant plasmids from chicken to chicken and from chicken to man. Nature 260:40
  • Licht, T.R., Christensen, B.B., Krogfelt, K.A., Molin, S., 19 Plasmid transfer in the animal intestine and other dynamic bacterial populations: the role of community structure and environment. Microbiol, 145: 2615-2622.
  • Lim, S.K., Lee, H.S., Nam, H.M., Cho, Y.S., Kim, J.M., Song, S.W., Park, Y.H., Jung, S.C., 2007. Antimicrobial resistance observed in Escherichia coli strains isolated from fecal samples of cattle and pigs in Korea during 2003–2004. Int. J. Food Microbiol, 116(2): 283-286.
  • Machado, E., Coque, T. M., Canton, R., Sousa, J. C., Peixe, L., 2008. Antibiotic resistance integrons and extended-spectrum β-lactamases among Enterobacteriaceae isolates recovered from chickens and swine in Portugal. J Antimicrob Chemother, 62: 296-30
  • Madec, J. Y., Lazizzera, C., Châtre, P., Meunier, D., Martin, S., Lepage, G., Ménard, M. F., Lebreton, P., Ramboud, T., 2008. Prevalence of fecal carriage of acquired-expanded-spectrum cephalosporin resistance in Enterobacteriaceae strains from cattle in France. J Clin Microb, 46:1566-1567.
  • Madec, J. Y., Poirel, L., Saras, E., Gourguechon, A., Girlich, D., Nordmann, P., Haenni, M., 2012. NonST131 Escherichia coli from cattle harbouring human-like blaCTX-M-15-carrying plasmids. J. Antimicrob. Chemother. 67:578-581.
  • Mammeri, H., Loo, M.V.D., Poirel, L., MartinezMartinez, L., Nordmann, L., 2005. Emergence of plasmid-mediated quinolone resistance in Escherichia coli in Europe. Antimicrob. Agents Chemother. 49(1): 71–76.
  • Marshall, B. M., Levy, S. B., 2011. Food animals and antimicrobials: impacts on human health. Clin. Microbiol. Rev. 24:718-733.
  • Mathew, A.G., Saxton, A.M., Upchurch, W.G., Chattin, S.E., 1999. Multiple antibiotic resistance patterns of Escherichia coli isolates from swine farms. Appl. Environ. Microbiol, 65(6): 2770-2772.
  • Mayrhofer, S., Paulsen, P., Smulders, F.J.M., Hilbert, F., 200 Short Communication: Antimicrobial resistance in commensal Escherichia coli isolated from muscle foods as related to the veterinary use of antimicrobial agents in food-producing animals in Austria. Microbial Drug Resistance, 12(4): 278 -283. Miles, T. D., McLaughlin, W., Brown, P.D., 2006. Antimicrobial resistance of Escherichia coli isolates from broiler chickens and humans. BMC Vet. Res, 2: Nirdnoy, W., 2005. The contribution of plasmids to antibiotic resistance in Campylobacter jejuni. Mahidol University, Faculty of graduate studies, Bangkok, Thailand. Dissertation.
  • Petridis, M., Bagdasarian, M., Waldor, M. K., Walker, E., 200 Horizontal transfer of shiga toxin and antibiotic resistance genes among Escherichia coli strains in house fly (Diptera: Muscidae) gut. J. Med. Entomol, 43(2): 288–295. Rasko, D. A., Webster, D. R., Sahl, J. W., Bashir, A., Boisen, N., Scheutz, F., Paxinos, E. E., Sebra, R., Chin, C. S., Iliopoulos, D., Klammer, A., Peluso, P., Lee, L., Kislyuk, A. O., Bullard, J., Kasarskis, A., Wang, S., Eid, J., Rank, D., Redman, J. C., Steyert, S. R., Frimodt-Moller, J., Struve, C., Petersen, A. M., Krogfelt, K. A., Nataro, J. P., Schadt, E. E., Waldor, M. K., 2011. Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N. Engl. J. Med. 365:709-717.
  • Rayamajhi, N., Kang, S. G., Lee, D. Y., Kang, M. L., Lee, S. I., Park, K. Y., Lee, H. S., Yoo, H. S., 2008. Characterization of TEM-, SHV- and AmpC-type βlactamases from cephalosporinresistant
  • Enterobacteriaceae isolated from swine. Int J Food Microb, 124:183-187. Riaño, I., Moreno, M. A., Teshager, T., Saenz, Y., Dominguez, L., Torres, C., 2006. Detection and characterization of extended-spectrum β-lactamases in Salmonella enterica strains of healthy food animals in Spain. J Antimicrob Chemother, 58: 8448
  • Sayah, R.S., Kaneene, J.B., Johnson, Y., Miller, R.A., 200 Patterns of antimicrobial resistance observed in Escherichia coli isolates obtained from domestic- and wild-animal fecal samples, human septage, and surface water. Appl. Environ. Microbiol, 71(3): 1394–1404.
  • Schjİrring, S., Struve, C., Krogfelt, K.A., 2005. Plasmid transfer from Klebsiella pneumoniae to Escherichia coli. 15th European Congress of Clinical Microbiology and Infectious Diseases. 2-5th April, Copenhagen, Denmark. http://www.blackwellpublishing.com/eccmid15/abstr act.asp?id=37125
  • Schröder, C., 200 Antimicrobial resistance in Escherichia coli isolates in a large German community-based hospital 1998–2003 trends correlated with antimicrobial use. 14th European Congress of Clinical Microbiology and Infectious Diseases (ESCMID), 1-4 May, Prague. http://www.blackwellpublishing.com/eccmid14/abstr act.asp?id=15619.
  • Shiraki, Y., Shibata, N., Doi, Y., Arakawa, Y., 2004. Escherichia coli producing CTX-M-2 betalactamase in cattle, Japan. Emerg Infect Dis, 10: 69
  • Smet, A., Martel, A., Persoons, D., Dewulf, J., Heyndrickx, M., Catry, B., Herman, L., Haesebrouck, F., Butaye, P., 2008. Diversity of extended-spectrum β-lactamases and class C βlactamases among cloacal Escherichia coli in Belgian broiler farms. Antimicrob Agents Chemother, 52: 1238-1243.
  • Sunde, M., Sorum, H., 2001. Self-transmissible multidrug resistance plasmids in Escherichia coli of the normal intestinal flora of healthy swine. Microb. Drug Resist, 7(2): 191-196.
  • Tian, G.B., Wang, H.N., Zou, L.K., Tang, J.N., Zhao, Y.W., Ye, M.Y., Tang, J.Y., Zhang, Y., Zhang, A.Y., Yang, X., Xu, C.W., Fu, Y.J., 2009. Detection of CTX-M-15, CTX-M-22 and SHV-2 extendedspectrum β-lactamases (ESBLs) in Escherichia coli fecal sample isolates from pig farms in China. Microb Drug Res, 3: 297-304.
  • Umolu, P.I., Ohenhen, E.R., Okwu, I.G., Ogiehor, I.S., 200 Multiple Antibiotic resistant index and plasmid of Escherichia coli in beef in Ekpoma. Am. J. Sci, 2(3): 1-4. VSPA (World Society for the Protection of Animals), 200 Resistant bacteria in people and farm animals around the world. http://wspafarmwelfare.org/hhantibiotics.html Winokur, P. L., Bruegegemann, A., DeSalvo, D. L., Hoffmann, L., Apley, M. D., Uhlenhopp, E. K., Pfaller, M. A., Doern, G. V., 2000. Animal and human multidrug-resistant Salmonella isolates expressing a plasmid-mediated CMY-2 AmpC βlactamase. Antimicrob Agents Chemother, 44: 277727
  • Wu, S., Chouliara, E., Hasman, H., Dalsgaard, A., Vieira, A., Jensen, L. B., 2008. Detection of a single isolate of CTX-M-1-producing Escherichia coli from healthy pigs in Denmark. J. Antimicrob. Chemother. 61:747-749.
  • Wu, S., Dalsgaard, A., Vieira, A. R., Emborg, H. D., Jensen, L. B., 2009. Prevalence of tetracycline resistance and genotypic analysis of populations of Escherichia coli from animals, carcasses and cuts processed at a pig slaughterhouse. Int. J. Food Microbiol. 135:254-259.
  • Yan, S.S., Gilbert, J.M., 2004. Antimicrobial drug delivery in food animals and microbial food safety concerns: An overview of in vitro and in vivo factors potentially affecting the animal gut micro flora. Adv. Drug. Deliv. Rev, 56(10): 1497-1521.
  • Zhao, S., Blickenstaff, K., Bodeis-Jones, S., Gaines, S. A., Tong, E., McDermott, P. F., 2012. A Comparison of the Prevalence and Antimicrobial Resistance of Escherichia coli from Different Retail Meats in the United States: 2002-2008. Appl. Environ. Microbiol. 78(6), 1701-1707. http://dx.doi.org/10.1128/AEM.07522-11
  • Zhao, S., White, D. G., Friedman, S. L., Glenn, A., Blickenstaff, K., Ayers, S. L., Abbott J.W, HallRobinson E, McDermott P.F. 2008. Antimicrobial resistance in Salmonella enterica serovar Heidelberg isolates from retail meats, including poultry, from 2002 to 2006. Appl Environ. Microbiol. 74 (21):6656doi: 10.1128/AEM.01249-08. Epub 2008 Aug 29.
Toplam 66 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm MİKROBİYOLOJİ (Microbiology)
Yazarlar

Karwan Mahmood Bu kişi benim

Emel Büyükünal Bal Bu kişi benim

Yayımlanma Tarihi 19 Kasım 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 17 Sayı: 1

Kaynak Göster

APA Mahmood, K., & Büyükünal Bal, E. (2014). Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer. KSÜ Doğa Bilimleri Dergisi, 17(1), 32-38. https://doi.org/10.18016/ksujns.71116
AMA Mahmood K, Büyükünal Bal E. Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer. KSÜ Doğa Bilimleri Dergisi. Kasım 2014;17(1):32-38. doi:10.18016/ksujns.71116
Chicago Mahmood, Karwan, ve Emel Büyükünal Bal. “Transmission of Antibiotic Resistant Enterobacteriaceae Between Animals and Humans Gastrointestinal Tract With the Evidence of in Vivo Plasmid Transfer”. KSÜ Doğa Bilimleri Dergisi 17, sy. 1 (Kasım 2014): 32-38. https://doi.org/10.18016/ksujns.71116.
EndNote Mahmood K, Büyükünal Bal E (01 Kasım 2014) Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer. KSÜ Doğa Bilimleri Dergisi 17 1 32–38.
IEEE K. Mahmood ve E. Büyükünal Bal, “Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer”, KSÜ Doğa Bilimleri Dergisi, c. 17, sy. 1, ss. 32–38, 2014, doi: 10.18016/ksujns.71116.
ISNAD Mahmood, Karwan - Büyükünal Bal, Emel. “Transmission of Antibiotic Resistant Enterobacteriaceae Between Animals and Humans Gastrointestinal Tract With the Evidence of in Vivo Plasmid Transfer”. KSÜ Doğa Bilimleri Dergisi 17/1 (Kasım 2014), 32-38. https://doi.org/10.18016/ksujns.71116.
JAMA Mahmood K, Büyükünal Bal E. Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer. KSÜ Doğa Bilimleri Dergisi. 2014;17:32–38.
MLA Mahmood, Karwan ve Emel Büyükünal Bal. “Transmission of Antibiotic Resistant Enterobacteriaceae Between Animals and Humans Gastrointestinal Tract With the Evidence of in Vivo Plasmid Transfer”. KSÜ Doğa Bilimleri Dergisi, c. 17, sy. 1, 2014, ss. 32-38, doi:10.18016/ksujns.71116.
Vancouver Mahmood K, Büyükünal Bal E. Transmission of Antibiotic Resistant Enterobacteriaceae between Animals and Humans Gastrointestinal Tract with the Evidence of in vivo Plasmid Transfer. KSÜ Doğa Bilimleri Dergisi. 2014;17(1):32-8.

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