In this study, antioxidant, antimicrobial activities and effects on DNA damage of above and below-ground extracts of Heliotropium samolifolium subsp. erzurumicum were determined. This subspecies distributes only in the vicinity of Olur (Erzurum) in Turkey and is known as Erzurum Bambulu by the people. Heliotropium L. species include secondary metabolities such as; pyrrolizidine alkaloids, terpenoids, saponins, phenols, flavonoids, tannis, and steroids. The above and below-ground extracts of the subspecies were prepared using different organic solvents. For the antioxidant studies, DPPH and total phenolic content calculation methods were applied. The antimicrobial activity tests of the extracts were performed using four different standard strains, a yeast and MIC (Minimum Inhibition Concentration) method. The effects on DNA damage of plant extracts were explained using pBR322 plasmid DNA. The below-ground ethanol extract of the subspecies was seen to have stronger antimicrobial activity. According to antioxidant data, the highest activity was found in above-ground ethanol+aqueous, chloroform and below-ground ethanol extracts. Also, the below-ground aqueous and chloroform extracts hada greater effect on the open ring form of pBR322 plasmid DNA. It was determined that the below ground extracts of the subspecies were more effective than the above ground extracts. It was suggested that the extracts obtained from this subspecies may be used in medicine industry and folk medicine.
|Journal Section||RESEARCH ARTICLE|
|Supporting Institution||Amasya University|
|Project Number||FMB-BAP 17-0286|
|Thanks||This study was produced within the scope of the project of FMB-BAP 17-0286 supported by Amasya University. This study is derived from master thesis Galip SAĞLAM's.|
: January 9, 2020
|APA||Sağlam, G , Kandemi̇r, N . (2020). Comparison of Biological and Antioxidant Activities of Above and Below-Ground Extracts of Endemic Heliotropium samolifolium subsp. erzurumicum . Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi , 23 (4) , 1054-1063 . DOI: 10.18016/ksutarimdoga.vi.672571|