In this study, antioxidant, antimicrobial activities and effects on DNA damage of above and below-ground extracts of Heliotropium samolifolium subsp. erzurumicum were determined. This subspecies distributes only in the vicinity of Olur (Erzurum) in Turkey and is known as Erzurum Bambulu by the people. Heliotropium L. species include secondary metabolities such as; pyrrolizidine alkaloids, terpenoids, saponins, phenols, flavonoids, tannis, and steroids. The above and below-ground extracts of the subspecies were prepared using different organic solvents. For the antioxidant studies, DPPH and total phenolic content calculation methods were applied. The antimicrobial activity tests of the extracts were performed using four different standard strains, a yeast and MIC (Minimum Inhibition Concentration) method. The effects on DNA damage of plant extracts were explained using pBR322 plasmid DNA. The below-ground ethanol extract of the subspecies was seen to have stronger antimicrobial activity. According to antioxidant data, the highest activity was found in above-ground ethanol+aqueous, chloroform and below-ground ethanol extracts. Also, the below-ground aqueous and chloroform extracts hada greater effect on the open ring form of pBR322 plasmid DNA. It was determined that the below ground extracts of the subspecies were more effective than the above ground extracts. It was suggested that the extracts obtained from this subspecies may be used in medicine industry and folk medicine.
Antimicrobial Antioxidant Endemic Heliotropium samolifolium Plasmid DNA
Amasya University
FMB-BAP 17-0286
This study was produced within the scope of the project of FMB-BAP 17-0286 supported by Amasya University. This study is derived from master thesis Galip SAĞLAM's.
Antimicrobial Antioxidant Endemic Heliotropium samolifolium Plazmit DNA
FMB-BAP 17-0286
Birincil Dil | İngilizce |
---|---|
Konular | Yapısal Biyoloji |
Bölüm | ARAŞTIRMA MAKALESİ (Research Article) |
Yazarlar | |
Proje Numarası | FMB-BAP 17-0286 |
Yayımlanma Tarihi | 31 Ağustos 2020 |
Gönderilme Tarihi | 9 Ocak 2020 |
Kabul Tarihi | 13 Mart 2020 |
Yayımlandığı Sayı | Yıl 2020Cilt: 23 Sayı: 4 |
2022-JIF = 0.500
2022-JCI = 0.170
Uluslararası Hakemli Dergi (International
Peer Reviewed Journal)
Dergimiz, herhangi bir başvuru veya yayımlama ücreti almamaktadır. (Free submission and publication)
Yılda 6 sayı yayınlanır. (Published 6 times a year)
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