Evaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa SubstanceEvaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa Substance

Rumeysa Duyuran; Metin Kılınç; Hasan Dağlı

doi:10.18016/ksutarimdoga.vi.1175469

TR EN

Verniks Kazeoza Maddesinde Bulunan Bazı Element (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Düzeylerinin Değerlendirilmesi

Öz

İnsan fetüsünun 3. trimestrinde salgılanmaya başlayan “Vernix Caseosa” (VC) maddesi kendiliğinden oluşan doğal bir üründür. Bebeği dış etkenlere karşı koruyan bu madde, normal doğum sırasında kayganlık sağlayarak doğumu kolaylaştıran bir özellik taşımaktadır. Çalışmaya 52 bebek dahil edilmiştir. VC toplanırken steril yumuşak uçlu aparat kullanılmıştır ve doğumdan hemen sonra bebeğin derisinden sürüntü şeklinde alınmıştır. Ayrıca 35 yaş altı ve 35 yaş üstü anneler, multipar ve nullipar olarak gruplandırılarak VC'si ayrı ayrı incelenmiştir. VC' da insan vücudunda bulunan, yapım ve onarımdan sorumlı elementlerin seviyeleri araştırılmıştır. Homojenize numuneler Atomik Absorbsiyon Spektrofotometre cihazı ölçülmüştür. Element sonuçları ortalama ve standart sapma olarak verildi; *Na+: 12.09 ± 0.58, *Cl-: 10.27 ± 1.08, *K+:1.84 ± 0.54, **Fe+2: 72.39 ± 4.84, **Mg+2: 67.07 ± 3.31, **Ca+2:864.51 ± 32.61, **Cu+2:12.98 ± 2.01, **Zn+2: 11.00 ± 1.55 (*:mg/g doku, **:ug/g doku). Literatür taramasının sonuçlarına göre ve bildindiği kadarıyla VC' nın element seviyeleri hakkında hiçbir bilgi rapor edilmemiştir. Çalışılan elementler, büyüme gelişmede ve birçok biyokimyasal mekanizmada kofaktör olarak bulunmaktadır. Daha önceki çalışmalarda protein ve lipid içerikleri araştırılmış ve VC'nin fetüsü dış etkenlerden ve enfeksiyonlardan korumada önemli rolü olduğu bildirilmiştir. Ek olarak amniyotik sıvının maserasyondan korunması ve cildin sıvı elektrolit kayıplarının önlenmesinden de bahsedilmiştir. Bu araştırmanın doğal ve koruyucu bir madde olan VC'nin biyokimyasal yapısının belirlenmesine önemli katkı sağlayacağı düşünülmektedir.

Anahtar Kelimeler

Evaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa SubstanceEvaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa Substance

Abstract

The substance "Vernix Caseosa" (VC), which begins to be secreted in the third trimester of the human fetus, is a natural product that occurs spontaneously. This substance, which protects the baby against external factors, has a feature that facilitates birth by providing lubrication during normal birth. 52 infants were included in the study. A sterile soft-tipped device was used to collect the VC, and a swab was taken from the baby's skin immediately after birth. In addition, mothers under the age of 35 and over the age of 35 were grouped as multiparous and nulliparous and their VC was examined separately. In VC, the levels of the elements responsible for production and repair in the human body were investigated. Homogenized samples were measured by Atomic Absorption Spectrophotometer. Element results were given as mean and standard deviation; *Na+: 12.09 ± 0.58, *Cl-: 10.27 ± 1.08, *K+:1.84 ± 0.54, **Fe+2: 72.39 ± 4.84, **Mg+2: 67.07 ± 3.31, **Ca+2:864.51 ± 32.61, **Cu+2:12.98 ± 2.01, **Zn+2: 11.00 ± 1.55 (*:mg/g tissue, **:ug/g tissue). According to the results of literature review and to the best of knowledge, limited information on element levels of VC has been reported. The studied elements are found as cofactors in growth and development and in many biochemical mechanisms. Protein and lipid contents have been investigated in previous studies and it has been reported that VC has an important role in protecting the fetus from external factors and infections. In addition, the protection of amniotic fluid from maceration and the prevention of fluid and electrolyte losses of the skin are also mentioned. It is thought that this research will make an important contribution to the determination of the biochemical structure of VC, which is a natural and protective substance.

Keywords

Thanks

The study was supported by the individual research projects unit of Kahramanmaras Sutcu Imam University.

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Rumeysa Duyuran ^*
0000-0002-7110-0303
Türkiye

Metin Kılınç
0000-0002-1623-0201
Türkiye

Hasan Dağlı
0000-0003-2756-6277
Türkiye

Publication Date

June 30, 2023

Submission Date

September 14, 2022

Acceptance Date

November 15, 2022

Published in Issue

Year 2023 Volume: 26 Number: 3

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1175469

IZ

https://izlik.org/JA25PH78UU

Cite

RIS / Bibtex

APA

Duyuran, R., Kılınç, M., & Dağlı, H. (2023). Evaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa SubstanceEvaluation of Some Elements (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Levels in Vernix Caseosa Substance. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 26(3), 471-476. https://doi.org/10.18016/ksutarimdoga.vi.1175469