TR
EN
Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster
Abstract
This research aimed to examine the anti-genotoxic properties of Stachys viscosa, a plant of the Lamiaceae family, which has medicinal and aromatic properties and is widely used in cosmetics, food, and pharmaceutical industries. The Drosophila wing somatic mutation and recombination test (SMART), an in vivo tool for evaluating somatic mutation and recombination, was employed. The anti-genotoxic effect of the S. viscosa plant against mitomycin C (MMC) mutagen was investigated. The study evaluated doses of 5 mg, 15 mg, 45 mg, and 60 mg of S. viscosa, concluding that doses of 45 mg and 60 mg effectively mitigated DNA damage induced by MMC. At doses of 45 mg and 65 mg, the total number of spots caused by MMC was suppressed by 8.21% and 13.17%, respectively. The data collected indicate that the S. viscosa plant possesses certain anti-genotoxic properties.
Keywords
References
- Al Snafi, A.E. (2013). The pharmaceutical importance of Althea officinalis and Althea rosea: A Review. International Journal of PharmTech Research, 5, 1378–1385.
- Boldbaatar, D., El-Seedi, H.R., Findakly, M., Jabri, S., Javzan, B., Choidash, B., Göransson, U., & Hellman, B. (2014). Antigenotoxic and antioxidant effects of the Mongolian medicinal plant Leptopyrum fumarioides (L): An in vitro study. Journal of Ethnopharmacology, 155(1), 599-606.
- Çelik, H., & Uysal, H. (2023). ‘Skualen’ triterpeninin somatik mutasyonlar üzerine etkisinin Drosophila melanogaster’de in vivo kanat benek testi ile araştırılması. KSÜ Tarım ve Doğa Dergisi, 26(3), 477-486.
- Çetinkaya, A.Y., & Yurtsever, S. (2021). Somatic mutations and recombination test in Drosophila melanogaster used for investigating the genotoxicity of some food additives. International Journal of Agriculture, Environment and Food Science, 5(1), 65-73.
- Duman, H., Kartal, M., Altun, L., Demirci, B., & Başer, K.H.C. (2005). The essential oil of Stachys laetivirens Kotschy & Boiss. ex Rech. fil., endemic in Turkey. Flavour and Fragrance Journal, 20(1), 48-50.
- El-Hefny, I., Hozayen, W., AlSenosy, N., Basal, W., Ahmed, A., & Diab, A. (2020). Evaluation of genotoxicity of three food preservatives in Drosophila melanogaster using Smart and Comet Assays. Journal of Microbiology, Biotechnology and Food Sciences, 10(1), 38-41.
- Gezici, S., Turkmen, M., & Karahan, F. (2024). Exploring the anti-cancer properties of essential oils from some Lamiaceae species against human cancer cells with multivariate analysis. South African Journal of Botany, 166, 287-296.
- Graf, U., Würgler, F.E., Katz, A.J., Frei, H., Juon, H., Hall, C.B., & Kale, P.G. (1984). Somatic mutation test in Drosophila melanogaster. Environmental Mutagenesis, 6, 153–88.
Details
Primary Language
English
Subjects
Entomology
Journal Section
Research Article
Early Pub Date
February 1, 2025
Publication Date
February 12, 2025
Submission Date
October 26, 2024
Acceptance Date
December 23, 2024
Published in Issue
Year 2025 Volume: 28 Number: 1
APA
Kılıç Karabulut, A., & Açar, M. (2025). Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 28(1), 53-61. https://doi.org/10.18016/ksutarimdoga.vi.1574067
AMA
1.Kılıç Karabulut A, Açar M. Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster. KSU J. Agric Nat. 2025;28(1):53-61. doi:10.18016/ksutarimdoga.vi.1574067
Chicago
Kılıç Karabulut, Aygül, and Mikail Açar. 2025. “Antigenotoxic Effects of Stachys Viscosa (Lamiaceae), a Potential Medicinal Plant in Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi 28 (1): 53-61. https://doi.org/10.18016/ksutarimdoga.vi.1574067.
EndNote
Kılıç Karabulut A, Açar M (February 1, 2025) Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 28 1 53–61.
IEEE
[1]A. Kılıç Karabulut and M. Açar, “Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster”, KSU J. Agric Nat., vol. 28, no. 1, pp. 53–61, Feb. 2025, doi: 10.18016/ksutarimdoga.vi.1574067.
ISNAD
Kılıç Karabulut, Aygül - Açar, Mikail. “Antigenotoxic Effects of Stachys Viscosa (Lamiaceae), a Potential Medicinal Plant in Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 28/1 (February 1, 2025): 53-61. https://doi.org/10.18016/ksutarimdoga.vi.1574067.
JAMA
1.Kılıç Karabulut A, Açar M. Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster. KSU J. Agric Nat. 2025;28:53–61.
MLA
Kılıç Karabulut, Aygül, and Mikail Açar. “Antigenotoxic Effects of Stachys Viscosa (Lamiaceae), a Potential Medicinal Plant in Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, vol. 28, no. 1, Feb. 2025, pp. 53-61, doi:10.18016/ksutarimdoga.vi.1574067.
Vancouver
1.Aygül Kılıç Karabulut, Mikail Açar. Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster. KSU J. Agric Nat. 2025 Feb. 1;28(1):53-61. doi:10.18016/ksutarimdoga.vi.1574067
