Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey

Aysun Mercimek Takcı; Kenan Canbaz; Sevil Toroglu; Menderes Çenet; Ferudun Koçer

doi:10.18016/ksutarimdoga.vi.1851697

TR EN

Türkiye'nin Kadirli Bölgesinde Yetişen Yabani Myrtus communis L. Bitkisinin Biyoaktivitesi ve Yağ Asitleri

Abstract

Akdeniz Havzası'nda yaygın olarak bulunan Myrtus communis L. (mersin), bazı rahatsızlıkların tedavisinde halk tıbbında kullanılmaktadır. Bu çalışma, Kadirli'den (Osmaniye) toplanan mersin yapraklarının kimyasal bileşimi ve biyolojik aktivitelerinin detaylı bir incelemesini sunmaktadır. Mayıs ve Ağustos 2022 tarihleri arasında, Türkiye'nin Osmaniye ilinin kuzey bölgesinden bitki örnekleri toplandı. M. communis L. yapraklarından farklı özütler hazırlandı. Bu özütlerin antimikrobiyal özellikleri, Kirby-Bauer disk difüzyon tekniği kullanılarak dokuz bakteri suşuna karşı test edildi. Ayrıca, antioksidan potansiyelleri DPPH serbest radikal temizleme ve Fe²⁺ şelasyon testleri ile değerlendirildi. GC-FID analizi, M. communis L.'de 10 farklı yağ asidini tanımladı. Başlıca bileşikler %26,274 oranında linoleik asit (omega-6) (C18:2), %21,961 oranında lignoserik asit (C24:0), %17,714 oranında nervonik asit (C24:1) ve %11,941 oranında cis-4,7,10,13,16,19-Dokosaheksaenoik asit idi. Mersin özütleri, Metisiline dirençli Staphylococcus aureus'a (MRSA) karşı 13,5-15 mm'lik bir zon ile önemli antibakteriyel aktivite gösterdi (BaL). Metanol ve etanol özütleri, Staphylococcus epidermidis B-4268, Escherichia coli JM109, Staphylococcus aureus 6538, metisiline dirençli Staphylococcus aureus (MRSA), vankomisine dirençli Enterococcus (VRE), Pseudomonas aeruginosa ve Escherichia coli K-12'ye karşı ˂10 mm'lik zon çaplarıyla daha yüksek antibakteriyel etkinlik göstermiştir. Metanol ve etanol özütleri, etil asetatın aksine, %24.49-26.18 aralığında ve 0.168-0.178 mg TE/g değerlerinde yüksek DPPH aktivitesi göstermiştir. Mersin (Myrtus communis L.) yapraklarının metanol ve etanol özütlerinin metal şelatlama aktiviteleri sırasıyla %60.47 (0.444 mg TE/g) ve %34.10 (0.250 mg) aralığında bulunmuştur. Sonuçlar, M. communis L. yapraklarının, muhtemelen yüksek doymamış yağ asitleri ve biyoaktif bileşik içeriği nedeniyle önemli antibakteriyel ve antioksidan aktivitelere sahip olduğunu göstermektedir. Bu bulgular, M. communis L. yapraklarını doğal antimikrobiyal ve antioksidan ajanlar için umut vadeden bir kaynak olarak vurgulamaktadır.

Keywords

Project Number

2022/4-1

Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey

Abstract

Myrtus communis L. (myrtle), largely distributing in the Mediterranean Basin, has been used in folk medicine for treating some ailments. This study presents a detailed investigation of myrtle leaves from Kadirli (Osmaniye), including its chemical composition, and biological activities. Between May and August 2022, plant samples were collected from the northern region of Osmaniye, Turkey. Leaves of M. communis L. were used to prepare different extracts. The antimicrobial properties of these extracts were tested against nine bacterial strains using the Kirby–Bauer disk diffusion technique. In addition, their antioxidant potential was evaluated through DPPH free radical scavenging and Fe²⁺ chelation assays. GC-FID analysis described 10 different fatty acids in M. communis L.. The major compounds were linoleic acid (omega-6) (C18:2) with 26.274%, lignoceric acid (C24:0) with 21.961%, nervonic acid (C24:1) with 17.714%, cis-4,7,10,13,16,19-Docosahexaenoic with 11. 941%. Myrtle extracts presented the significant antibacterial activity of 13.5-15 mm zone to Methicillin Resistant Staphylococcus aureus (MRSA) (BaL). The methanol and ethanol extracts demonstrated greater antibacterial efficacy against Staphylococcus epidermidis B-4268, Escherichia coli JM109, Staphylococcus aureus 6538, methicillin-resistant Staphylococcus aureus (MRSA,), vancomycin-resistant Enterococcus (VRE, Pseudomonas aeruginosa and Escherichia coli K-12 with zone diameters of ˂10 mm. Methanol and ethanol extracts, in contrast to ethyl acetate, showed high DPPH activity, with 24.49-26.18% values ranging from 0.168-0.178 mg TE/g. The metal chelating activities of methanolic and ethanolic extracts of Myrtus communis L. leaves revealed in the range of 60.47% (0.444 mg TE/g) and 34.10% (0.250 mg TE/g), respectively. The results indicate that M. communis L. leaves exhibit significant antibacterial and antioxidant activities, likely due to their high content of unsaturated fatty acids and bioactive compounds. These findings highlight M. communis L. leaves as a promising source of natural antimicrobial and antioxidant agents.

Keywords

Project Number

2022/4-1

Thanks

The authors would like to acknowledge the Kahramanmaraş Sütçü İmam University KSÜ BAP (scientific research projects unit) Project (NO: 2022/4-1) for financial support to the realization of these studies. The authors also would like to thank 1) the Kahramanmaraş Sütçü İmam University, ÜSKİM (University, Industry, Public Cooperation Development Application and Research Center) and 2) Çankırı Karatekin University, Central Research Laboratory Application and Research Center for providing laboratory facilities to conducting these studies.

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Details

Primary Language

English

Subjects

Plant Biotechnology

Journal Section

Research Article

Authors

Aysun Mercimek Takcı ^*
0000-0002-3388-1153
Türkiye

Kenan Canbaz
0000-0003-4718-1251
Türkiye

Sevil Toroglu
0000-0001-8667-6383
Türkiye

Menderes Çenet
0000-0002-9644-7741
Türkiye

Ferudun Koçer
0000-0002-8749-7106
Türkiye

Early Pub Date

November 7, 2026

Publication Date

-

Submission Date

December 30, 2025

Acceptance Date

June 11, 2026

Published in Issue

Year 2026 Number: Advanced Online Publication

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1851697

IZ

https://izlik.org/JA48BP52EE

Cite

RIS / Bibtex

APA

Mercimek Takcı, A., Canbaz, K., Toroglu, S., Çenet, M., & Koçer, F. (2026). Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, Advanced Online Publication. https://doi.org/10.18016/ksutarimdoga.vi.1851697

AMA

1.Mercimek Takcı A, Canbaz K, Toroglu S, Çenet M, Koçer F. Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey. KSU J. Agric Nat. 2026;(Advanced Online Publication). doi:10.18016/ksutarimdoga.vi.1851697

Chicago

Mercimek Takcı, Aysun, Kenan Canbaz, Sevil Toroglu, Menderes Çenet, and Ferudun Koçer. 2026. “Bioactivity and Fatty Acids of Wild Myrtus Communis L. In Kadirli, Turkey”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, no. Advanced Online Publication. https://doi.org/10.18016/ksutarimdoga.vi.1851697.

EndNote

Mercimek Takcı A, Canbaz K, Toroglu S, Çenet M, Koçer F (November 7, 2026) Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi Advanced Online Publication

IEEE

[1]A. Mercimek Takcı, K. Canbaz, S. Toroglu, M. Çenet, and F. Koçer, “Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey”, KSU J. Agric Nat., no. Advanced Online Publication, Nov. 2026, doi: 10.18016/ksutarimdoga.vi.1851697.

ISNAD

Mercimek Takcı, Aysun - Canbaz, Kenan - Toroglu, Sevil - Çenet, Menderes - Koçer, Ferudun. “Bioactivity and Fatty Acids of Wild Myrtus Communis L. In Kadirli, Turkey”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi. Advanced Online Publication (November 7, 2026). https://doi.org/10.18016/ksutarimdoga.vi.1851697.

JAMA

1.Mercimek Takcı A, Canbaz K, Toroglu S, Çenet M, Koçer F. Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey. KSU J. Agric Nat. 2026. doi:10.18016/ksutarimdoga.vi.1851697.

MLA

Mercimek Takcı, Aysun, et al. “Bioactivity and Fatty Acids of Wild Myrtus Communis L. In Kadirli, Turkey”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, no. Advanced Online Publication, Nov. 2026, doi:10.18016/ksutarimdoga.vi.1851697.

Vancouver

1.Aysun Mercimek Takcı, Kenan Canbaz, Sevil Toroglu, Menderes Çenet, Ferudun Koçer. Bioactivity and Fatty Acids of Wild Myrtus communis L. in Kadirli, Turkey. KSU J. Agric Nat. 2026 Nov. 7;(Advanced Online Publication). doi:10.18016/ksutarimdoga.vi.1851697