In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Serhat Keser; Fatma Keser; İsmail Turkoglu; Omer Kaygılı; Suat Tekın; Ersin Demır; Mustafa Karatepe; Okkes Yılmaz; Sevda Kırbag; Suleyman Sandal; Semra Turkoglu

doi:10.18016/ksutarimdoga.vi.589279

TR EN

In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Abstract

Centaurea L. species were used as medicinal plants among the people for treatment of the common cold, abscesses, peptic ulcers, hemorrhoid and diabetes etc.. In the present study, antiradical properties, phytochemical contents, antimicrobial and antiproliferative activities of three Centaurea species were investigated. Centaurea saligna (K.Koch) Wagenitz methanol (99.94%), Centaurea virgata Lam. methanol (98.23%) and water (98.10%) extracts were showed higher ABTS scavenging than trolox (96.79%). Centaurea kurdica Reichardt extracts showed lower activity than trolox for all the antiradical assays. Centaurea extracts exhibited antimicrobial activity against to some microorganisms. It was determined that these Centaurea species contain high amount of total flavonoid, phenolic and proanthocyanidin, phenolic acids, phytosterols and unsaturated fatty acids. Also, three Centaurea extracts showed very high antiproliferative property on LNCaP, HCT-116, MCF-7 cancer cell lines.

Keywords

Centaurea,Endemic,Antiradical,Phytochemical,Antiproliferative

Supporting Institution

TÜBİTAK

Project Number

114Z124

Thanks

This study was supported by TUBITAK, under grant number 114Z124.

References

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Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Serhat Keser ^*
0000-0002-9678-1053
Türkiye

Fatma Keser
0000-0001-6870-0546
Türkiye

İsmail Turkoglu
0000-0001-7454-7605
Türkiye

Omer Kaygılı
0000-0002-2321-1455
Türkiye

Suat Tekın
0000-0002-2757-1802
Türkiye

Ersin Demır
0000-0002-7676-5953
Türkiye

Mustafa Karatepe
0000-0001-6358-5913
Türkiye

Okkes Yılmaz
0000-0002-8276-4498
Türkiye

Sevda Kırbag
0000-0002-4337-8236
Türkiye

Suleyman Sandal
0000-0002-8916-3329
Türkiye

Semra Turkoglu
0000-0001-7682-0513
Türkiye

Publication Date

February 28, 2020

Submission Date

July 9, 2019

Acceptance Date

September 26, 2019

Published in Issue

Year 2020 Volume: 23 Number: 1

DOI

https://doi.org/10.18016/ksutarimdoga.vi.589279

IZ

https://izlik.org/JA33RC78EJ

Cite

RIS / Bibtex

APA

Keser, S., Keser, F., Turkoglu, İ., Kaygılı, O., Tekın, S., Demır, E., Karatepe, M., Yılmaz, O., Kırbag, S., Sandal, S., & Turkoglu, S. (2020). In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 23(1), 148-156. https://doi.org/10.18016/ksutarimdoga.vi.589279

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Clinical and Experimental Health Sciences

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In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Doğu Anadolu, Türkiye’de Yetişen Üç Centaurea L. Türünün in vitro Biyolojik Değerlendirilmesi ve Fitokimyasal Özellikleri

Öz

Anahtar Kelimeler

In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Abstract

Keywords

Supporting Institution

Project Number

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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Cited By

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