Investigation of Nutritional Content, Antioxidant Anticancer and Antimicrobial Activities of Pleurotus eryngii (DC. Ex Fr.) Quel, Extract Obtained by Different Solvents

Hilal Acay; Abdurrahman Dündar; Semra Kaçar; Mehmet Fırat Baran; Cumali Keskin

doi:10.18016/ksutarimdoga.vi.742646

EN TR

Investigation of Nutritional Content, Antioxidant Anticancer and Antimicrobial Activities of Pleurotus eryngii (DC. Ex Fr.) Quel, Extract Obtained by Different Solvents

Abstract

The present study related the nutritional contents, fatty acid compositions, in vitro antioxidant, anticancer and antimicrobial activities of different solvents extracts of Pleurotus eryngii. The nutritional contents of the P. eryngii were investigated in detail. Crude protein (g 100 kg-1), carbohydrate (g 100 kg-1), lipid (g 100 kg-1), ash (g 100 kg-1), dietary fiber (g 100 kg-1) and energy value (cal 100 g-1) of fruiting bodies were analysed. Fatty acid compositions of total lipid, phospholipid and triacylglycerol fractions of Pleurotus eryngii were investigated by Gas chromatography. Totally 13 different fatty acids constituents were identified. Antioxidant properties including total antioxidant activity, free radical scavenging activity, reducing power activity, metal chelating activity, and superoxide anion radical scavenging activity were evaluated using different tests. The highest total antioxidant, DPPH scavenging, metal chelating, and superoxide anion radical scavenging activities were determined in ethyl acetate extracts. The potential of cytotoxic activity on PC-3 (prostate cancer) cell lines was found to depend on the concentration and the type of the tested extracts fractions. It was determined that hexane, ethyl acetate, and methanol extracts of Pleurotus eryngii have inhibition effect on the growth of tested microorganisms. The present results suggested that used as a daily nutrient, the Pleurotus eryngii could be a novel source for new drug developments and promising in some cancer treatment.

Keywords

Pleurotus eryngii (DC. Ex Fr.) Quel’in Farklı Çözücülerle Elde Edilen Özütlerinin Besinsel Içeriğinin, Antioksidan Antikanser ve Antimikrobiyal Aktivitelerinin Araştırılması

Öz

Bu çalışma Pleurotus eryngii'nin farklı çözücü ekstraktlarının besinsel içerikleri, yağ asidi bileşimleri, in vitro antioksidan, antikanser ve antimikrobiyal aktiviteleri ile ilgilidir. P. eryngii'nin besinsel içeriği ayrıntılı olarak araştırıldı. Meyve gövdesinin ham protein (g 100 kg-1), karbonhidrat (g 100 kg-1), lipit (g 100 kg-1), kül (g 100 kg-1), diyet lifi (g 100 kg-1) ve enerji değeri (100 g-1) analiz edildi. Pleurotus eryngii'nin toplam lipit, fosfolipid ve triaçilgliserol fraksiyonlarının yağ asidi bileşimleri Gaz kromatografisi ile araştırıldı. Toplam 13 farklı yağ asidi bileşeni belirlendi. Toplam antioksidan aktivite, serbest radikal süpürme aktivitesi, indirgeme gücü aktivitesi, metal şelatlama aktivitesi ve süperoksit anyon radikali süpürme aktivitesini içeren antioksidan özellikler farklı testler kullanılarak değerlendirildi. En yüksek toplam antioksidan, DPPH radikali süpürme, metal şelatlama ve süperoksit anyon radikal süpürme aktiviteleri etil asetat özütünde belirlendi. PC-3 (prostat kanseri) hücre hattı üzerindeki sitotoksik aktivite potansiyelinin, test edilen özüt fraksiyonlarının konsantrasyonuna ve tipine bağlı olduğu bulundu. Pleurotus eryngii'nin heksan, etil asetat ve metanol ekstraktlarının, test edilen mikroorganizmaların büyümesini inhibe edici etkiye sahip olduğu belirlendi. Mevcut sonuçlar, günlük besin olarak kullanılan Pleurotus eryngii'nin yeni ilaç gelişmeleri ve bazı kanser tedavilerinde umut vaat eden yeni bir kaynak olabileceğini düşündürmektedir.

Anahtar Kelimeler

Supporting Institution

Mardin Artuklu University

Project Number

MAÜ -15- SYO- 04

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Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Hilal Acay
0000-0002-7732-106X
Türkiye

Abdurrahman Dündar
0000-0002-7930-1054
Türkiye

Semra Kaçar
0000-0002-9869-9045
Türkiye

Mehmet Fırat Baran
0000-0001-8133-6670
Türkiye

Cumali Keskin ^*
0000-0003-3758-0654
Türkiye

Publication Date

April 30, 2021

Submission Date

May 27, 2020

Acceptance Date

July 28, 2020

Published in Issue

Year 2021 Volume: 24 Number: 2

DOI

https://doi.org/10.18016/ksutarimdoga.vi.742646

IZ

https://izlik.org/JA79TF97SU

Cite

RIS / Bibtex

APA

Acay, H., Dündar, A., Kaçar, S., Baran, M. F., & Keskin, C. (2021). Investigation of Nutritional Content, Antioxidant Anticancer and Antimicrobial Activities of Pleurotus eryngii (DC. Ex Fr.) Quel, Extract Obtained by Different Solvents. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 24(2), 267-277. https://doi.org/10.18016/ksutarimdoga.vi.742646

Cited By

Fumaria parviflora Lam. ve Fumaria capreolata L.’nin Antioksidan ve Sitotoksik Aktiviteleri

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi

https://doi.org/10.18016/ksutarimdoga.vi.899937