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Valeriana dioscoridis Sm. Ekstraktlarının Biyoaktivite ve Fitokimyasal Kompozisyon Değişimleri

Year 2021, Volume: 24 Issue: 4, 738 - 746, 31.08.2021

Esra Uçar , Mehmet Ataş , Yeter Çilesiz İlker Çinbilgel , Nuraniye Eruygur , Tolga Karaköy

https://doi.org/10.18016/ksutarimdoga.vi.799598

Abstract

Kedi otu (Valeriana dioscoridis Sm.) Caprifoliaceae familyasının çok yıllık bitkisidir. Bu çalışmanın amacı tüketimi gittikçe artan bitkilerden olan V. dioscoridis bitkisinin besin değerleri, ekstrakt içerikleri, antioksidan ve antimikrobiyal aktivite değerleri gibi kalite kriterleri yönünden, farklı bölgelerde yetişen bitkilerin toplandığı bölgelere gore her hangi bir farklılık oluşturup oluşturmadığının belirlenmesi içindir. Bu çalışmada Valeriana dioscoridis Sm. kök ve rizomları Antalya ilinin sekiz farklı bölgesinden toplanmıştır. Elde edilen materyaller toz haline getirilmiş ve % 80 etanol ile ekstrakte edilmiştir. Toz halindeki bitki örneklerinin makro ve mikro besin elemet içerikleri değerlendirilmiş ve ekstraktların da antioksidan ve antimikrobiyal aktiviteleri değerlendirilmiştir. Elde edilen verilere gore farklı bölgelerde yetişen Valeriana dioscoridis Sm. bitki ekstratlarının antioksidan, antimikrobiyal aktiviteleri ve besin içerikleri ve kimyasal kompozisyonunda farklı değerler elde edilmiştir.

Keywords

Antioksidan Antimikrobiyal Caprifoliaceae Makro ve Mikro Elements Valeriana dioscoridis

References

  • Aktaş M, Ateş A 1998. Bitkilerde Beslenme Bozuklukları Nedenleri Tanınmaları. Nurol Matbaacılık A.Ş. Ostim-Ankara.
  • Awouafack MD, McGaw LJ, Gottfried S, Mbouangouere R, Tane P, Spiteller M,Eloff JN 2013. Antimicrobial Activity and Cytotoxicity of the Ethanol Extract, Fractions and Eight Compounds Isolated from Eriosema robustum (Faba-ceae). BMC Complem Altern M,13:289.
  • Blois MS 1958. Antioxidant determinations by the use of a stable free radical. Nature 181:1199-2000.
  • Bogacz A, Mrozikiewicz PM, Karasiewicz M, Bartkowiak-Wieczorek J, Majchrzycki M, Mikolajczak PL, Ozarowski M, Grzeskowiak E 2014. “The Influence of Standardized Valeriana officinalis Extract on the CYP3A1 Gene Expression by Nuclear Receptors in In Vivo Model”. Hindawi Publishing Corporation BioMed Research International Article ID 819093, 7 pages.
  • Bremner JM 1965. “Method of Soil Analysis. Part 2. Chemical and Microbiological Methods”. American Society of Agronomy Inc. Madison, Wise USA, 1149-1178.
  • Bulut Y 2006. Useful Plants of Manavgat (Antalya) Region. Süleyman Demirel University. Institute of Science, Department of Biology. Master Thesis. Isparta. 107 p. Isparta.
  • Ceylan A 1987. Tıbbi Bitkiler II., Ege Üniversitesi Ziraat Fakültesi Yayınları No: 481, İzmir.
  • Clarke G, Ting K, Wiart C, Fry J 2013. High Correlation of 2,2-diphenyl-1-picrylhydrazyl (DPPH) Radical Scavenging, Ferric Reducing Activity Potential and Total Phenolics Content Indicates Redundancy in Use of All Three Assays to Screen for Antioxidant Activity of Extracts of Plants from the Malaysian rainforest. Antioxidants, 2(1): 1-10.
  • CLSI 2002. Reference Method for Broth Dilution Antifungal Suscept-ibility Testing of Yeasts, Approved Standard (2nd ed.). Pennsylva¬nia: Clinical and Laboratory Standards Institute.
  • CLSI 2012. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, Approved Standard. In CLSI (2nd ed.). Pennsylvania: Clinical and Laboratory Standards Institute. Davis PH, Mill RR, Tan K 1988. Flora of Turkey and the East Aegean Islands. 10:155, Edinburgh Univ. Press., Edinburgh.
  • Dimpfel W 2007. Acute Effect of a Valerian Root Extract on Depth of Sleep in Humans (German). Z Phytother, 28(1): 7-15. Abstract from CABA 2008:183113.
  • Ekbiç E, Fidan H, Selim E 2017. The Effect of Cucumber Mosaic Virus (CMV) on Plant Nutrient Content in Cucumber. Academic Journal of Agriculture, 6: 263-268.
  • Eloff JN 1998. A Sensitive and Quick Microplate Method to Determine The Minimal Inhibitory Concentration of Plant Extracts For Bacteria. Planta Med. 64: 711-713.
  • Eruygur N, Dural E 2019. Determination of 1-Deoxynojirimycin by a Developed and Validated HPLCFLD Method and Assessment of In-Vitro Antioxidant, Α-Amylase and Α-Glucosidase Inhibitory Activity in Mulberry Varieties from Turkey. Phytomedicine, 53: 234-242.
  • Guarrera PM, Lucchese F, Medori S 2008. Ethnophytotherapeutical Research in the High Molise Region (Central-Southern Italy). Journal of Ethnobiology and Ethnomedicine, 4(1): 1-11.
  • Güner A, Özhatay N, Ekim T, Başer KHC 2000. Flora of Turkey and the East Aegean Islands. 11: 147, Edinburgh Univ. Press., Edinburgh.
  • Güner A, Aslan S, Ekim T, Vural M, Babaç MT (edlr) 2012. Turkey Plants List (Vascular Plants). Publication of Nezahat Gökyiğit Botanical Garden and Flora Research Association, Istanbul.
  • Güzel N, Gülüt KY, Ortaş İ, İbrikçi H 1992. “Soil Productivity Analysis Methods Laboratory Handbook”. Faculty of Agriculture Yay. No: 117, Adana.
  • Halvorsen B, Holte K, Myhrstad M, Barigmo I, Hvattum E, Remberg S 2002. A Systematic Screening of Total Antioxidants in Dietary Plants. J. Nutr,132 (3): 461-471.
  • Halliwell B 1997. Antioxidant and Human Disease: A General Introduction. Nutrition Reviews, 55(1): 44-52.
  • Inglet GE, Chen D, Berhow M, Lee S 2011. Antioxidant Activity of Commercial Buck Wheat Flours and Their Free and Bound Phenolic Compositions. Food Chem., 125: 923-929.
  • İçli N 2017. Determination of Total Phenolic Compounds, Total Antıoxidant Capacity and Total Flavonoid Compounds in Apple Sour. Health Academy Kastamonu, 2(2): 89-99.
  • Karadeniz A, Çinbilgel İ, Gün SŞ, Çetin A 2015. Antioxidant activity of Some Turkish Medicinal Plants. Nat. Prod. Res., 29(24): 2308-2312.
  • Kuete V 2010. Potential of Cameroonian Plants and Derived Products Against Microbial Infections: a review. Planta Med. 76: 1479–1491.
  • Lopez-Munoz F, Alamo C,Garcia-Garcia P 2006. The Herbs That Have the Property of Healing…,”: The Phytotherapy in Don Quixote. Journal of Ethnopharmacology 106: 429–441.
  • Molan AL, Mahdy AS 2014. Iraqi Medicinal Plants: Total Flavonoid Contents, Free-Radical Scavenging and Bacterial Beta-Glucuronidase Inhibition Activities. IOSR Journal of Dental and Medical Sciences, 13(5): 72-7.
  • Murphy L, Rıley JP 1962. “A Modified Single Solution Method for the Determination of Phosphate in Natural Waters”. Analytica Chimica Acta, 27: 31-36.
  • Naczk M, Shahidi F 2004. Extraction and Analysis of Phenolics in Food. J. Chromatogr A, 1054: 95-111.
  • Petenatti ME, Petenatti EM, Del Vitto LA, Téves MR, Caffini NO, Marchevsky EJ, Pellerano RG 2011. Evaluation of Macro and Microminerals in Crude Drugs and Infusions of Five Herbs Widely Used as Sedatives. Rev. Bras Farmacog, 21(6): 1144-1149.
  • Piccinelli AL, Arana S, Caceres AD, Sorrentino R, Rastrelli L 2004. “New Lignans from the Roots of Valeriana prionophylla with Antioxidative and Vasorelaxant Activities”. J.Nat Prod.,67: 1135–1140.
  • Plaster EJ 1992. Soil Science and Management. 2nd Edition, Delmar Publishers Inc., Albany, New York, USA. Re R, Pellegrini N, Proteggente A, Pannalaa A, MinYang Rice-Evans C, Rice-Evans 1999. Antioxidant Activity Applying an Improved ABTS Radical Cation Decolorization Assay. Free Radic. Biol. Med. 26: 1231–1237.
  • Richardson IBK 1972. Valeriana L. In.: Davis, P.H. Flora of Turkey and the East Aegean Islands, 4: 551-558. Edinburgh Univ. Press., Edinburgh.
  • Sacchetti G, Maietti S, Muzzoli M, Scaglianti M, Manfredini S, Radice M, Bruni R 2005. Comparative Evaluation of 11 Essential Oils of Different Origin as Functional Antioxidants, Antiradicals and Antimicrobials in Foods. Food Chem., 91: 621-632.
  • Saddiqe Z, Naeem I, Maimoona A 2010. A Review of the Antibacterial Activity of Hypericum perforatum L. J Ethnopharmacol,131(3): 511–521.
  • Tzakou O, Couladis M, Pavlovic M,Sokovic M 2004. Composition and Antifungal Activity of The Oil from Aerial Parts and Rhizomes of Valeriana dioscoridis from Greece. J. Essent. Oil Res., 16 (5): 500-503.
  • Yen GC, Wu JY 1999. Antioxidant and Radical Scavenging Properties of Extracts from Ganoderma tsugae. Food Chem., 65: 375-379..

Variation of Bioactivities and Phytochemical Compositions of Valeriana dioscoridis Sm. Extracts

Year 2021, Volume: 24 Issue: 4, 738 - 746, 31.08.2021

Esra Uçar , Mehmet Ataş , Yeter Çilesiz İlker Çinbilgel , Nuraniye Eruygur , Tolga Karaköy

https://doi.org/10.18016/ksutarimdoga.vi.799598

Abstract

Valerian (Valeriana dioscoridis Sm.) is a perennial herb of the Caprifoliaceae family. The aim of this study was to determine the variation of V. dioscoridis plants grown in different regions in respect of the quality criteria traits such as nutrient values, extract contents and in vitro antioxidant and antimicrobial activity values. In this study, roots and rhizomes of V. dioscoridis Sm. were collected from eight different locations in Antalya province. The obtained materials were ground in a blender and extracted with 80% ethanol. The macro and micro-nutrient elements contents of the powdered plant samples were evaluated and the antioxidant and antimicrobial activities of the extracts were investigated. Based on the data obtained, there were different values in the antioxidant, antimicrobial activities, nutrient content and chemical composition content of extracts of V.dioscoridis Sm. plants grown in different locations.

Keywords

Antioksidan Antimikrobiyal Caprifoliaceae Makro ve Mikro Element Valeriana dioscoridis

References

  • Aktaş M, Ateş A 1998. Bitkilerde Beslenme Bozuklukları Nedenleri Tanınmaları. Nurol Matbaacılık A.Ş. Ostim-Ankara.
  • Awouafack MD, McGaw LJ, Gottfried S, Mbouangouere R, Tane P, Spiteller M,Eloff JN 2013. Antimicrobial Activity and Cytotoxicity of the Ethanol Extract, Fractions and Eight Compounds Isolated from Eriosema robustum (Faba-ceae). BMC Complem Altern M,13:289.
  • Blois MS 1958. Antioxidant determinations by the use of a stable free radical. Nature 181:1199-2000.
  • Bogacz A, Mrozikiewicz PM, Karasiewicz M, Bartkowiak-Wieczorek J, Majchrzycki M, Mikolajczak PL, Ozarowski M, Grzeskowiak E 2014. “The Influence of Standardized Valeriana officinalis Extract on the CYP3A1 Gene Expression by Nuclear Receptors in In Vivo Model”. Hindawi Publishing Corporation BioMed Research International Article ID 819093, 7 pages.
  • Bremner JM 1965. “Method of Soil Analysis. Part 2. Chemical and Microbiological Methods”. American Society of Agronomy Inc. Madison, Wise USA, 1149-1178.
  • Bulut Y 2006. Useful Plants of Manavgat (Antalya) Region. Süleyman Demirel University. Institute of Science, Department of Biology. Master Thesis. Isparta. 107 p. Isparta.
  • Ceylan A 1987. Tıbbi Bitkiler II., Ege Üniversitesi Ziraat Fakültesi Yayınları No: 481, İzmir.
  • Clarke G, Ting K, Wiart C, Fry J 2013. High Correlation of 2,2-diphenyl-1-picrylhydrazyl (DPPH) Radical Scavenging, Ferric Reducing Activity Potential and Total Phenolics Content Indicates Redundancy in Use of All Three Assays to Screen for Antioxidant Activity of Extracts of Plants from the Malaysian rainforest. Antioxidants, 2(1): 1-10.
  • CLSI 2002. Reference Method for Broth Dilution Antifungal Suscept-ibility Testing of Yeasts, Approved Standard (2nd ed.). Pennsylva¬nia: Clinical and Laboratory Standards Institute.
  • CLSI 2012. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, Approved Standard. In CLSI (2nd ed.). Pennsylvania: Clinical and Laboratory Standards Institute. Davis PH, Mill RR, Tan K 1988. Flora of Turkey and the East Aegean Islands. 10:155, Edinburgh Univ. Press., Edinburgh.
  • Dimpfel W 2007. Acute Effect of a Valerian Root Extract on Depth of Sleep in Humans (German). Z Phytother, 28(1): 7-15. Abstract from CABA 2008:183113.
  • Ekbiç E, Fidan H, Selim E 2017. The Effect of Cucumber Mosaic Virus (CMV) on Plant Nutrient Content in Cucumber. Academic Journal of Agriculture, 6: 263-268.
  • Eloff JN 1998. A Sensitive and Quick Microplate Method to Determine The Minimal Inhibitory Concentration of Plant Extracts For Bacteria. Planta Med. 64: 711-713.
  • Eruygur N, Dural E 2019. Determination of 1-Deoxynojirimycin by a Developed and Validated HPLCFLD Method and Assessment of In-Vitro Antioxidant, Α-Amylase and Α-Glucosidase Inhibitory Activity in Mulberry Varieties from Turkey. Phytomedicine, 53: 234-242.
  • Guarrera PM, Lucchese F, Medori S 2008. Ethnophytotherapeutical Research in the High Molise Region (Central-Southern Italy). Journal of Ethnobiology and Ethnomedicine, 4(1): 1-11.
  • Güner A, Özhatay N, Ekim T, Başer KHC 2000. Flora of Turkey and the East Aegean Islands. 11: 147, Edinburgh Univ. Press., Edinburgh.
  • Güner A, Aslan S, Ekim T, Vural M, Babaç MT (edlr) 2012. Turkey Plants List (Vascular Plants). Publication of Nezahat Gökyiğit Botanical Garden and Flora Research Association, Istanbul.
  • Güzel N, Gülüt KY, Ortaş İ, İbrikçi H 1992. “Soil Productivity Analysis Methods Laboratory Handbook”. Faculty of Agriculture Yay. No: 117, Adana.
  • Halvorsen B, Holte K, Myhrstad M, Barigmo I, Hvattum E, Remberg S 2002. A Systematic Screening of Total Antioxidants in Dietary Plants. J. Nutr,132 (3): 461-471.
  • Halliwell B 1997. Antioxidant and Human Disease: A General Introduction. Nutrition Reviews, 55(1): 44-52.
  • Inglet GE, Chen D, Berhow M, Lee S 2011. Antioxidant Activity of Commercial Buck Wheat Flours and Their Free and Bound Phenolic Compositions. Food Chem., 125: 923-929.
  • İçli N 2017. Determination of Total Phenolic Compounds, Total Antıoxidant Capacity and Total Flavonoid Compounds in Apple Sour. Health Academy Kastamonu, 2(2): 89-99.
  • Karadeniz A, Çinbilgel İ, Gün SŞ, Çetin A 2015. Antioxidant activity of Some Turkish Medicinal Plants. Nat. Prod. Res., 29(24): 2308-2312.
  • Kuete V 2010. Potential of Cameroonian Plants and Derived Products Against Microbial Infections: a review. Planta Med. 76: 1479–1491.
  • Lopez-Munoz F, Alamo C,Garcia-Garcia P 2006. The Herbs That Have the Property of Healing…,”: The Phytotherapy in Don Quixote. Journal of Ethnopharmacology 106: 429–441.
  • Molan AL, Mahdy AS 2014. Iraqi Medicinal Plants: Total Flavonoid Contents, Free-Radical Scavenging and Bacterial Beta-Glucuronidase Inhibition Activities. IOSR Journal of Dental and Medical Sciences, 13(5): 72-7.
  • Murphy L, Rıley JP 1962. “A Modified Single Solution Method for the Determination of Phosphate in Natural Waters”. Analytica Chimica Acta, 27: 31-36.
  • Naczk M, Shahidi F 2004. Extraction and Analysis of Phenolics in Food. J. Chromatogr A, 1054: 95-111.
  • Petenatti ME, Petenatti EM, Del Vitto LA, Téves MR, Caffini NO, Marchevsky EJ, Pellerano RG 2011. Evaluation of Macro and Microminerals in Crude Drugs and Infusions of Five Herbs Widely Used as Sedatives. Rev. Bras Farmacog, 21(6): 1144-1149.
  • Piccinelli AL, Arana S, Caceres AD, Sorrentino R, Rastrelli L 2004. “New Lignans from the Roots of Valeriana prionophylla with Antioxidative and Vasorelaxant Activities”. J.Nat Prod.,67: 1135–1140.
  • Plaster EJ 1992. Soil Science and Management. 2nd Edition, Delmar Publishers Inc., Albany, New York, USA. Re R, Pellegrini N, Proteggente A, Pannalaa A, MinYang Rice-Evans C, Rice-Evans 1999. Antioxidant Activity Applying an Improved ABTS Radical Cation Decolorization Assay. Free Radic. Biol. Med. 26: 1231–1237.
  • Richardson IBK 1972. Valeriana L. In.: Davis, P.H. Flora of Turkey and the East Aegean Islands, 4: 551-558. Edinburgh Univ. Press., Edinburgh.
  • Sacchetti G, Maietti S, Muzzoli M, Scaglianti M, Manfredini S, Radice M, Bruni R 2005. Comparative Evaluation of 11 Essential Oils of Different Origin as Functional Antioxidants, Antiradicals and Antimicrobials in Foods. Food Chem., 91: 621-632.
  • Saddiqe Z, Naeem I, Maimoona A 2010. A Review of the Antibacterial Activity of Hypericum perforatum L. J Ethnopharmacol,131(3): 511–521.
  • Tzakou O, Couladis M, Pavlovic M,Sokovic M 2004. Composition and Antifungal Activity of The Oil from Aerial Parts and Rhizomes of Valeriana dioscoridis from Greece. J. Essent. Oil Res., 16 (5): 500-503.
  • Yen GC, Wu JY 1999. Antioxidant and Radical Scavenging Properties of Extracts from Ganoderma tsugae. Food Chem., 65: 375-379..
There are 36 citations in total.

Details

Primary Language English
Journal Section RESEARCH ARTICLE
Authors

Esra Uçar 0000-0001-6327-4779

Mehmet Ataş 0000-0002-9425-0080

Yeter Çilesiz 0000-0002-4313-352X

İlker Çinbilgel 0000-0003-3084-5998

Nuraniye Eruygur 0000-0002-4674-7009

Tolga Karaköy 0000-0002-5428-1907

Publication Date August 31, 2021
Submission Date September 24, 2020
Acceptance Date December 17, 2020
Published in Issue Year 2021Volume: 24 Issue: 4

Cite

APA Uçar, E., Ataş, M., Çilesiz, Y., Çinbilgel, İ., et al. (2021). Variation of Bioactivities and Phytochemical Compositions of Valeriana dioscoridis Sm. Extracts. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 24(4), 738-746. https://doi.org/10.18016/ksutarimdoga.vi.799598
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