Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species

Çiğdem Aydın; Ramazan Mammadov

doi:10.18016/ksutarimdoga.vi.1179200

EN TR

Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species

Abstract

The purpose of this study was to look into the in vitro anthelmintic activities of methanol extracts of Hyacinthella lineata (Steud. ex Schult. & Schult.f.) Chouard, Ornithogalum umbellatum L., Allium reuterianum Boiss., Cyclamen coum Mill., and Sternbergia clusiana (Ker Gawl.) Ker Gawl. ex Spreng.. The paralysis and death times of the Indian earthworm, Cosmocerca ornata, were used to assess anthelmintic activity. Three different concentrations, (5,10 and 20 mg mL-1) of methanol extracts were used to determine the time required to paralyze and to induce death in the earthworms. Albendazole (15 mg mL-1) was used as reference standard drug. Plant extracts at higher concentrations (20 mg mL-1) produced faster paralytic effects and a shorter time to death. The results revealed that S. clusiana killed all of the test worms within 20 ± 0.6 min of exposure and was 100% effective. Among all five plants extracts tested, S. clusiana was found to be highly effective and significant against C. ornata. The findings will aid in understanding the significance and application of these medicinal plant species in the food industry, traditional medicine, and pharmaceutical applications. This anthelmintic study of the plant extracts revealed that traditional medicine may be as effective as modern medicine in combating pathogenic micro-organisms.

Keywords

Beş Farklı Geofit Bitki Türünden Elde Edilen Metanolik Ekstraktların ın vitro Antihelmint Aktivitesinin Araştırılması

Abstract

Bu çalışma Hyacinthella lineata, Ornithogalum umbellatum, Allium reuterianum, Cyclamen coum, Sternbergia clusiana türleri metanol ekstraktlarının in vitro antihelmintik aktivitelerini araştırmak için tasarlanmıştır. Hint toprak solucanı Cosmocerca ornata’nın paraliz ve ölüm zamanının hesaplanması ile antihelmint aktivite değerlendirilmesi yapılmıştır. Paraliz ve ölüme yol açan süreyi belirlemek için üç farklı konsantrasyon (5,10 ve 20 mg mL-1) kullanılmıştır. Referans standart olarak Albendazol (15 mg mL-1) kullanılmıştır. Bitki özütleri yüksek konsantrasyonlarda (20 mg mL-1) daha hızlı paralitik etkiler ve daha kısa zamanda ölüm göstermiştir. Sonuçlar göstermiştir ki, Sternbergia clusiana türüne maruz kalan test solucanlarının tümü 20±0.6 dakika içinde ölüm göstererek %100 etkili olmuştur. Beş bitki türü arasında S. clusiana'nın solucanlara (Cosmocerca ornata) karşı oldukça etkili olduğu ve önemli sonuçlar verdiği bulunmuştur. Sonuçlar, bu tıbbi türlerin gıda endüstrisindeki, geleneksel tıptaki ve farmasötik uygulamalardaki önemini ve kullanımını anlamamıza yardımcı olacaktır. Bitki özleri üzerinde yapılan bu antelmintik çalışma, geleneksel tıbbın patojenik mikroorganizmaların üstesinden gelmek için modern tıp kadar etkili olabileceğini ortaya koydu.

Keywords

Supporting Institution

PAMUKKALE ÜNİVERSİTESİ BAP Birimi, Doktora Projesinden

Thanks

PAMUKKALE ÜNİVERSİTESİ BAP Birimine katkılarından dolayı teşekkür ederiz

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Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Çiğdem Aydın ^*
0000-0003-1934-9766
Türkiye

Ramazan Mammadov
0000-0003-2218-5336
Türkiye

Publication Date

December 30, 2022

Submission Date

September 23, 2022

Acceptance Date

November 6, 2022

Published in Issue

Year 2022 Volume: 25 Number: Ek Sayı 2

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1179200

IZ

https://izlik.org/JA74BF48FM

Cite

RIS / Bibtex

APA

Aydın, Ç., & Mammadov, R. (2022). Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 25(Ek Sayı 2), 376-381. https://doi.org/10.18016/ksutarimdoga.vi.1179200

AMA

1.Aydın Ç, Mammadov R. Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species. KSU J. Agric Nat. 2022;25(Ek Sayı 2):376-381. doi:10.18016/ksutarimdoga.vi.1179200

Chicago

Aydın, Çiğdem, and Ramazan Mammadov. 2022. “Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi 25 (Ek Sayı 2): 376-81. https://doi.org/10.18016/ksutarimdoga.vi.1179200.

EndNote

Aydın Ç, Mammadov R (December 1, 2022) Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 25 Ek Sayı 2 376–381.

IEEE

[1]Ç. Aydın and R. Mammadov, “Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species”, KSU J. Agric Nat., vol. 25, no. Ek Sayı 2, pp. 376–381, Dec. 2022, doi: 10.18016/ksutarimdoga.vi.1179200.

ISNAD

Aydın, Çiğdem - Mammadov, Ramazan. “Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 25/Ek Sayı 2 (December 1, 2022): 376-381. https://doi.org/10.18016/ksutarimdoga.vi.1179200.

JAMA

1.Aydın Ç, Mammadov R. Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species. KSU J. Agric Nat. 2022;25:376–381.

MLA

Aydın, Çiğdem, and Ramazan Mammadov. “Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, vol. 25, no. Ek Sayı 2, Dec. 2022, pp. 376-81, doi:10.18016/ksutarimdoga.vi.1179200.

Vancouver

1.Çiğdem Aydın, Ramazan Mammadov. Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species. KSU J. Agric Nat. 2022 Dec. 1;25(Ek Sayı 2):376-81. doi:10.18016/ksutarimdoga.vi.1179200