EN
TR
Anthelmintic Activities of Methanol Extracts of Five Different Geophyte Plant Species
Abstract
The purpose of this study was to look into the in vitro anthelmintic activities of methanol extracts of Hyacinthella lineata (Steud. ex Schult. & Schult.f.) Chouard, Ornithogalum umbellatum L., Allium reuterianum Boiss., Cyclamen coum Mill., and Sternbergia clusiana (Ker Gawl.) Ker Gawl. ex Spreng.. The paralysis and death times of the Indian earthworm, Cosmocerca ornata, were used to assess anthelmintic activity. Three different concentrations, (5,10 and 20 mg mL-1) of methanol extracts were used to determine the time required to paralyze and to induce death in the earthworms. Albendazole (15 mg mL-1) was used as reference standard drug. Plant extracts at higher concentrations (20 mg mL-1) produced faster paralytic effects and a shorter time to death. The results revealed that S. clusiana killed all of the test worms within 20 ± 0.6 min of exposure and was 100% effective. Among all five plants extracts tested, S. clusiana was found to be highly effective and significant against C. ornata. The findings will aid in understanding the significance and application of these medicinal plant species in the food industry, traditional medicine, and pharmaceutical applications. This anthelmintic study of the plant extracts revealed that traditional medicine may be as effective as modern medicine in combating pathogenic micro-organisms.
Keywords
Destekleyen Kurum
PAMUKKALE ÜNİVERSİTESİ BAP Birimi, Doktora Projesinden
Teşekkür
PAMUKKALE ÜNİVERSİTESİ BAP Birimine katkılarından dolayı teşekkür ederiz
Kaynakça
- Aydin C, Mammadov R 2017. Phenolic Composition, Antioxidant, Antibacterial, Larvacidal Against Culex pipiens and Cytotoxic Activites of Hyacinthella lineata Steudel Extracts. International Journal of Food Properties 20(10): 2276-2285.
- Berkov S, Bastida J, Tsvetkova R, Viladomat F, Codina C 2009. Alkaloids from Sternbergia colchiciflora. Z Naturforsch 64: 311-316.
- Blessing O, Ezea Omonike O, Edith O 2019. Ajaiyeoba In vitro anthelmintic properties of root extracts of three Musa species Journal Pharmacy & Bioresources 16(2): 145-151.
- Bokov DO, Krasikova MK, Sergunova EV, Bobkova NV, Kovaleva TY, Bondar AA, et al. 2020. Pharmacognostic, Phytochemical and Ethnopharmacological Potential of Cyclamen coum Mill. Pharmacogn J 12(1): 204-212.
- Chybowski J 1997. Study of the anthelmintic activity of garlic extracts. Herba Polonica 43: 383-387.
- Dall'acqua S, Castagliuolo I, Brun P, Ditadi F, Palu G, Innocenti G. 2010. Triterpene Glycosides With in Vitro Anti-Inflammatory Activity From Cyclamen repandum tubers Carbohydrate Research 30: 345- 709.
- Davis PH, 1978. Flora of Turkey and East Aegean Islands. Vol. 6. Edinburgh University of Edinburgh Press, Edinburgh: 128-135.
- Delazar A, Nazifi E, Movafeghi A, Nahar L, Nazemiyeh H, Moghadam SB, Asnaashari S, Sarker SD 2009. Gc-Ms Analysis Of Ornithogalum procerum. Daru 17(1): 33-36.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Yapısal Biyoloji
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
30 Aralık 2022
Gönderilme Tarihi
23 Eylül 2022
Kabul Tarihi
6 Kasım 2022
Yayımlandığı Sayı
Yıl 2022 Cilt: 25 Sayı: Ek Sayı 2
