Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

Burcin Yalcin; Merve Güneş; Ayşen Yağmur Kurşun; Ghada Tagorti; Ezgi Golal; Bülent Kaya

doi:10.18016/ksutarimdoga.vi.1224968

TR EN

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Öz

Birçok insektisit formülasyonunda kullanılan sentetik bir piretroid olan tetramethrin kalıntılarının çevre sağlığı ve canlı organizmalar üzerindeki olumsuz etkileri endişe konusudur. Bu çalışmanın amacı, tetrametrin'in hedef dışı bir organizma olan Drosophila melanogaster üzerindeki genotoksik ve gelişimsel etkilerini değerlendirmektir. Bu nedenle Drosophila hemositlerinde komet testi kullanılarak DNA hasarı üzerindeki etkisi, Drosophila kanat SMART kullanılarak da mutasjenik ve rekombinojenik etkileri değerlendirilmiştir. Ayrıca tetramethrin'in Drosophila gelişimi üzerindeki etkileri larva ağırlığı, larva uzunluğu ve yumurta verimi ölçülerek değerlendirilmiştir. Sonuçlar, tetrametrin'in sadece yüksek konsantrasyonda larva ağırlığında ve uzunluğunda bir azalmaya neden olduğunu göstermiştir. Ayrıca yumurta veriminde konsantrasyona bağlı bir şekilde azalma gözlenmiştir. Komet testi sonuçlarına göre, % DNA'da anlamlı bir artış olmadığı için DNA hasarı indüklenmemiştir. Ancak tetrametrin, SMART testinde mitotik rekombinasyonu indükleyerek genotoksisiteye neden olmuştur.

Anahtar Kelimeler

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Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Burcin Yalcin
0000-0002-9694-5839
Türkiye

Merve Güneş
0000-0003-3278-0542
Türkiye

Ayşen Yağmur Kurşun
0000-0003-1657-6808
Türkiye

Ghada Tagorti
0000-0003-4597-8320
Türkiye

Ezgi Golal
0000-0002-7685-7479
Türkiye

Bülent Kaya ^*
0000-0002-0491-9781
Türkiye

Early Pub Date

January 21, 2024

Publication Date

April 1, 2024

Submission Date

January 3, 2023

Acceptance Date

September 7, 2023

Published in Issue

Year 1970 Volume: 27 Number: 2

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1224968

IZ

https://izlik.org/JA36BP97LH

Cite

RIS / Bibtex

APA

Yalcin, B., Güneş, M., Kurşun, A. Y., Tagorti, G., Golal, E., & Kaya, B. (2024). Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 27(2), 304-315. https://doi.org/10.18016/ksutarimdoga.vi.1224968

Cited By

Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi

https://doi.org/10.18016/ksutarimdoga.vi.1574067

Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Öz

Anahtar Kelimeler