Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

Burcin Yalcin; Merve Güneş; Ayşen Yağmur Kurşun; Ghada Tagorti; Ezgi Golal; Bülent Kaya

doi:10.18016/ksutarimdoga.vi.1224968

TR EN

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Abstract

Birçok insektisit formülasyonunda kullanılan sentetik bir piretroid olan tetramethrin kalıntılarının çevre sağlığı ve canlı organizmalar üzerindeki olumsuz etkileri endişe konusudur. Bu çalışmanın amacı, tetrametrin'in hedef dışı bir organizma olan Drosophila melanogaster üzerindeki genotoksik ve gelişimsel etkilerini değerlendirmektir. Bu nedenle Drosophila hemositlerinde komet testi kullanılarak DNA hasarı üzerindeki etkisi, Drosophila kanat SMART kullanılarak da mutasjenik ve rekombinojenik etkileri değerlendirilmiştir. Ayrıca tetramethrin'in Drosophila gelişimi üzerindeki etkileri larva ağırlığı, larva uzunluğu ve yumurta verimi ölçülerek değerlendirilmiştir. Sonuçlar, tetrametrin'in sadece yüksek konsantrasyonda larva ağırlığında ve uzunluğunda bir azalmaya neden olduğunu göstermiştir. Ayrıca yumurta veriminde konsantrasyona bağlı bir şekilde azalma gözlenmiştir. Komet testi sonuçlarına göre, % DNA'da anlamlı bir artış olmadığı için DNA hasarı indüklenmemiştir. Ancak tetrametrin, SMART testinde mitotik rekombinasyonu indükleyerek genotoksisiteye neden olmuştur.

Keywords

Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

Abstract

The adverse effects of tetramethrin residues, a synthetic pyrethroid used in many insecticide formulations, on environmental health and living organisms are a matter of concern. The aim of this study was to evaluate the genotoxic and developmental effects of tetramethrin in a non-target organism, Drosophila melanogaster. Thus, its effect on DNA damage was evaluated using the Comet assay in hemocytes, and its mutagenic and recombinogenic effects were evaluated using Drosophila wing SMART. Also, the effects of tetramethrin on Drosophila development were evaluated by measuring larval weight, larval length, and fecundity. Results showed that tetramethrin induced a decrease in the larval weight and length only at a high concentration. Moreover, a decrease in fecundity in a dose-dependent manner was observed. According to the Comet assay results, DNA damage was not induced because there was no significant increase in % DNA. However, tetramethrin caused genotoxicity by inducing mitotic recombination in the SMART assay.

Keywords

References

Abdulbaki H, & Al-Deeb M.A (2023). Neuroprotective effects of ferulic acid and thymoquinone against deltamethrin-induced neurotoxicity in Drosophila melanogaster. Advancements in life sciences, 10(2), 289-297.
Abeyasuriya K.G.T.N, Nugapola N.W.N.P, Perera M.D.B, Karunaratne W.A.I.P & Karunaratne S.H.P.P. (2017). Effect of dengue mosquito control insecticide thermal fogging on non-target insects. International Journal of Tropical Insect Science, 37(1), 11–18. https://doi.org/10.1017/S1742758416 000254.
Abrahams, P.J., Houweling, A., Schouten, R., van der Eb, A.J. & Terleth, C. (2003). Abnormal kinetics of induction of UV-stimulated recombination in human DNA repair disorders. DNA Repair, 2(11), 1211-1225. https://doi.org/10.1016/S1568-7864 (03) 00141-1.
Anushree, Ali, M. Z., Bilgrami, A. L., & Ahsan, J. (2023). Acute exposure to arsenic affects pupal development and neurological functions in Drosophila melanogaster. Toxics, 11(4), 327. https://doi.org/10.3390/toxics11040327
Arias, M., Bonetto, C., & Mugni, H. (2020). Sublethal effects on Simocephalus vetulus (Cladocera: Daphnidae) of pulse exposures of cypermethrin. Ecotoxicology and environmental safety, 196, 110546. https://doi.org/10.1016/j.ecoenv.2020. 110546
Arslan, P. (2022). Determinations of the effects of cyfluthrin on the hemocytes parameters of freshwater mussel (Unio delicatus). Ege Journal of Fisheries and Aquatic Sciences, 39(1), 39-45. https://doi.org/10.12714/egejfas.39.1.06
Ballesteros, M. L., Boyle, R. L., Kellar, C. R., Miglioranza, K. S. B., Bistoni, M. A., Pettigrove, V., & Long, S. M. (2020). What types of enzyme activities are useful biomarkers of bifenthrin exposure on Chironomus sp. (Diptera, Chironomidae) larvae under laboratory and field-based microcosm conditions? Aquatic toxicology (Amsterdam, Netherlands), 228, 105618. https://doi.org/10.1016/j.aquatox.2020.105618
Barrios-Arpi, L., Arias, Y., Lopez-Torres, B., Ramos-Gonzalez, M., Ticli, G., Prosperi, E., & Rodríguez, J. L. (2022). In vitro neurotoxicity of flumethrin pyrethroid on SH-SY5Y neuroblastoma cells: Apoptosis associated with oxidative stress. Toxics, 10(3), 131. https://doi.org/10.3390/toxics10030131

Batiste-Alentorn, M., Xamena, N., Velázquez, A., Creus, A., & Marcos, R. (1986). Mutagenicity testing of the pyrethroid insecticide cypermethrin in Drosophila. Mutagenesis, 1(5), 343–346. https://doi.org/10.1093/mutage/1.5.343
Bej, S., Ghosh, K., Chatterjee, A., & Saha, N. C. (2021). Assessment of biochemical, hematological and behavioral biomarkers of Cyprinus carpio on exposure to a type-II pyrethroid insecticide Alpha-cypermethrin. Environmental toxicology and pharmacology, 87, 103717. https://doi.org/10.1016/ j.etap.2021.103717
Beken, A. T., Saka, Ş., Aydın, İ., Fırat, K., Suzer, C., Benzer, F., Erişir, M., Özden, O., Hekimoğlu, M. A., Engin, S., & Antepli, O. (2022). In vivo and in vitro evolution of the effects of cypermethrin on turbot (Scophthalmus maximus, Linnaeus, 1758) spermatozoa. Comparative biochemistry and physiology Part C: Toxicology & Pharmacology, 256, 109298. https://doi.org/10.1016/j.cbpc.2022.109298
Berry-III, R. & Lopez-Martinez, G. (2020). A dose of experimental hormesis: When mild stress protects and improves animal performance. Comparative Biochemistry and Physiology, Part A, 242, 110658. https://doi.org/10.1016/j.cbpa.2020.110658.
Çavuşoğlu, K., Kaya, A., Yilmaz, F., & Yalçin, E. (2012). Effects of cypermethrin on Allium cepa. Environmental toxicology, 27(10), 583–589. https://doi.org/10.1002/tox.20681
Charpentier, G., Louat, F., Bonmatin, J. M., Marchand, P. A., Vanier, F., Locker, D., & Decoville, M. (2014). Lethal and sublethal effects of imidacloprid, after chronic exposure, on the insect model Drosophila melanogaster. Environmental science & technology, 48(7), 4096–4102. https://doi.org/10.1021/es405331c
Charreton, M., Decourtye, A., Henry, M., Rodet, G., Sandoz, J. C., Charnet, P., & Collet, C. (2015). A locomotor deficit induced by sublethal doses of pyrethroid and neonicotinoid insecticides in the honeybee Apis mellifera. PloS one, 10(12), e0144879. https://doi.org/10.1371/journal.pone. 0144879
Chedik, L., Bruyere, A., Vee, M.L., Stieger, B., Denizot, C., Parmentier, Y., Potin, S. & Fardel, O. (2017). Inhibition of human drug transporter activities by the pyrethroid pesticides allethrin and tetramethrin. PLoS One, 12(1), e0169480. https://doi.org/10.1371/journal.pone.0169480.
Chen, X., Wang, Y., Wu, W., Dong, K., & Hu, Z. (2018). DSC1 channel-dependent developmental regulation of pyrethroid susceptibility in Drosophila melanogaster. Pesticide biochemistry and physiology, 148, 190–198. https://doi.org/10.1016/ j.pestbp.2018.04.014
Corcellas, C., Andreu, A., Manez, M., Sergio, F., Hiraldo, F., Eljarrat, E. & Barcelo, D. (2017). Pyrethroid insecticides in wild bird eggs from a World Heritage Listed Park: A case study in Donana National Park (Spain). Environmental Pollution, 228, 321-330. https://doi.org/10.1016/ j.envpol.2017.05.035.
Cruces, M. P., Pimentel, E., Vidal, L. M., Jiménez, E., Suárez, H., Camps, E., & Campos-González, E. (2023). Genotoxic action of bifenthrin nanoparticles and its effect on the development, productivity, and behavior of Drosophila melanogaster. Journal of toxicology and environmental health. Part A, 86(18), 661–677. https://doi.org/10.1080/15287394. 2023.2234408
Demir, E., Kocaoğlu, S. & Kaya, B. (2008). Genotoxicity testing of four benzyl derivaties in the Drosophila wing spot test. Food and Chemical Toxicology, 46(3), 1034-1041. https://doi.org/10.1016/ j.fct.2007. 10.035.
Dhawan, A., Bajpayee, M. & Parmar, D. (2009). Comet assay: a reliable tool for the assessment of DNA damage in different models. Cell Biology and Toxicology, 25(1), 5–32. https://doi.org/10.1007/ s10565-008-9072-z.
Dikmen, B.Y., Vejselova, D., Kutlu, H.M., Filazi, A, & Erkoç, F. (2018). Effects of synthetic pyrethroids on RTG-2 cells. Toxin Reviews, 37(4), 304-312. https://doi.org/10.1080/15569543.2017.1366922.
Elser, B. A., Hing, B., & Stevens, H. E. (2022). A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides. Critical reviews in toxicology, 52(5), 371–388. https://doi.org/10.1080/10408444.2022.2122769
Frei, H. & Würgler, F.E. (1988). Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive results. Mutation Research/ Environmental Mutagenesis and Related Subjects, 203(4), 297–308. https://doi.org/10.1016/ 0165-1161(88)90019-2.
Frei, H., Clements, J., Howe, D. & Würgler, F.E. (1992). The genotoxicity of the anticancer drug mitoxantrone in somatic and germ cells of Drosophila melanogaster. Mutation Research, 279(1), 21-33. https://doi.org/10.1016/0165-1218(92)90262-x.
Göl, E., Çok, İ., Battal, D., & Şüküroğlu, A. A. (2023). Assessment of preschool children's exposure levels to organophosphate and pyrethroid pesticide: A human biomonitoring study in two Turkish provinces. Archives of environmental contamination and toxicology, 84(3), 318–331. https://doi.org/10.1007/s00244-023-00986-3
Graf, U., Würgler, F.E., Katz, A.J., Frei, H., Juon, H., Hall, C. B. & Kale, P.G. (1984). Somatic mutation and recombination test in Drosophila melanogaster. Environmental Mutagenesis, 6(2), 153-188. https://doi.org/10.1002/em.2860060206.
Greno, M., Amariei, G., Boltes, K., Castro-Puyana, M., García, M. A., & Marina, M. L. (2021). Ecotoxicity evaluation of tetramethrin and analysis in agrochemical formulations using chiral electrokinetic chromatography. The Science of the total environment, 800, 149496. https://doi.org/ 10.1016/j.scitotenv.2021.149496
Horton, M.K., Jacobson, J.B., Mckelvey, W., Holmes, D., Fincher, B., Quantano, A., Diaz, B.P., Shabbazz, F., Shepard, P., Rundle, A. & Whyatt, R.M. (2011). Characterization of residential pest control products used in inner-city communities in New York City. Journal of Exposure Science and Environmental Epidemiology, 21(3), 291-301. https://doi.org/10.1038/jes.2010.18.
Huff Hartz, K. E., Weston, D. P., Johanif, N., Poynton, H. C., Connon, R. E., & Lydy, M. J. (2021). Pyrethroid bioaccumulation in field-collected insecticide-resistant Hyalella azteca. Ecotoxicology, 30(3), 514–523. https://doi.org/10.1007/s10646-021-02361-1
Ileriturk, M., & Kandemir, F. M. (2023). Carvacrol protects against λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity by modulating oxidative stress, inflammation, apoptosis, endoplasmic reticulum stress, and autophagy. Environmental toxicology, 38(7), 1535-1547. https://doi.org/10.1002/tox.23784
Ileriturk, M., Kandemir, O., & Kandemir, F. M. (2022). Evaluation of protective effects of quercetin against cypermethrin-induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and endoplasmic reticulum stress pathway. Environmental toxicology, 37(11), 2639–2650. https://doi.org/10.1002/tox.23624
Irving, P., Ubeda, J.M., Doucet, D., Troxler, L., Lagueux, M., Zachary, D., Hoffmann, J.A., Hetru, C. & Meister, M. (2005). New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cellular Microbiology, 7(3), 335-350. https://doi.org/10.1111/j.1462-5822. 2004. 00462.x.
Jameel, M., Alam, M. F., Younus, H., Jamal, K., & Siddique, H. R. (2019). Hazardous sub-cellular effects of Fipronil directly influence the organismal parameters of Spodoptera litura. Ecotoxicology and environmental safety, 172, 216–224. https://doi.org/ 10.1016/j.ecoenv.2019.01.076
Kadala, A., Charreton, M., Charnet, P., Cens, T., Rousset, M., Chahine, M., Vaissière, B. E., & Collet, C. (2019). Voltage-gated sodium channels from the bees Apis mellifera and Bombus terrestris are differentially modulated by pyrethroid insecticides. Scientific reports, 9(1), 1078. https://doi.org/ 10.1038/s41598-018-37278-z
Kadala, A., Charreton, M., Jakob, I., Cens, T., Rousset, M., Chahine, M., Le Conte, Y., Charnet, P., & Collet, C. (2014). Pyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons. PloS one, 9(11), e112194. https://doi.org/10.1371/journal.pone.0112194
Kadala, A., Charreton, M., Jakob, I., Le Conte, Y., & Collet, C. (2011). A use-dependent sodium current modification induced by type I pyrethroid insecticides in honeybee antennal olfactory receptor neurons. Neurotoxicology, 32(3), 320–330. https://doi.org/10.1016/j.neuro.2011.02.007
Karadeniz, A., Kaya, B., Savaş, B. & Topcuoğlu, Ş.F. (2011). Effects of two plant growth regulators, indole-3-acetic acid and beta-naphthoxyacetic acid, on genotoxicity in Drosophila SMART assay and on proliferation and viability of HEK293 cells from the perspective of carcinogenesis. Toxicology and Industrial Health, 27(9), 840-848. https://doi.org/ 10.1177/0748233711399314.
Karataş, A., & Bahçeci, Z. (2009). Effect of cypermethrin on some developmental stages of Drosophila melanogaster. Bulletin of environmental contamination and toxicology, 82(6), 738–742. https://doi.org/10.1007/s00128-008-9604-5
Kastenbaum, M.A. & Bowman, K.O. (1970). Tables for determining the statistical significance of mutation frequencies. Mutation Research, 9(5), 527-549. https://doi.org/10.1016/0027-5107(70)90038-2.
Kaya, B., Kocaoğlu, S. & Demir, E. (2006). Analysis of UV-stimulated recombination in the Drosophila SMART assay. Environmental and Molecular Mutagenesis, 47(5), 357-361. https://doi.org/ 10.1002/em.20215.
Kaya, B., Marcos, R., Yanıkoğlu, A. & Creus, A. (2004). Evaluation of the genotoxicity of four herbicides in the wing spot test of Drosophila melanogaster using two different strains. Mutation Research. 557(1), 53-62. https://doi.org/10.1016/ j.mrgentox.2003. 09.010.
Kaya, B., Yanıkoğlu, A. & Marcos, R. (1999). Genotoxicity studies on the phenoxyacetates 2,4-D and 4-CPA in the Drosophila wing spot test. Teratagen Careinagen and Mutagen, 19, 305-312.
Kim, S.S., Kwack, S.J., Lee, R.D., Lim, K.J., Rhee, G.S., Seok, J.H., Kim, B.H., Won, Y.H., Lee, G.S., Jeung, E.B., Lee, B.M. & Park, K.L. (2005). Assessment of estrogenic and androgenic activities of tetramethrin in vitro and in vivo assays. Journal of Toxicology and Environmental Health Part A, 68(23-24), 2277-2289. https://doi.org/10.1080/ 15287390500182453.
Kissoum, N., Gheraibia, H.B., Hamida, Z.C. & Soltani, N. (2020). Evaluation of the pesticide Oberon on a model organism Drosophila melanogaster via topical toxicity test on biochemical and reproductive parameters. Comparative Biochemistry and Physiology, Part C Pharmacolgy, 228, 108666. https://doi.org/10.1016/j.cbpc.2019.108666.
Klopic, I., Kolsek, K. & Dolenc, M.S. (2015). Glucocorticoid-like activity of propylparaben, butylparaben, diethylhexyl phthalate and tetramethrin mixtures studied in the MDA-kb2 cell line. Toxicology Letters, 232(2), 376–383. https://doi.org/10.1016/j.toxlet.2014.11.019.
Kumaravel, T.S. & Jha, A.N. (2006). Reliable Comet assay measurements for detecting DNA damage induced by ionising radiation and chemicals. Mutation Research, 605(1-2), 7–16. https://doi.org/ 10.1016/j.mrgentox.2006.03.002.
Kuzukiran, O., Simsek, I., Yorulmaz, T., Dikmen, B.Y., Ozkan, O. & Filazi, A. (2021). Multiresidues of environmental contaminants in bats from Turkey. Chemosphere, 282, 131022. https://doi.org/ 10.1016/j.chemosphere.2021.131022.
Lesseur, C., Kaur, K., Kelly, S. D., Hermetz, K., Williams, R., Hao, K., Marsit, C. J., Caudle, W. M., & Chen, J. (2023). Effects of prenatal pesticide exposure on the fetal brain and placenta transcriptomes in a rodent model. Toxicology, 490, 153498. https://doi.org/10.1016/j.tox.2023.153498
Li, H., Cheng, F., Wei, Y., Lydy, M.J. & You, J. (2017). Global occurrence of pyrethroid insecticides in sediment and the associated toxicological effects on benthic invertebrates: An overview. Journal of Hazardous Materials, 324(part B), 258-271. https://doi.org/10.1016/j.jhazmat.2016.10.056.
Lindsley, D.L. & Zimm, G.G. (1992). The genome of Drosophila melanogaster. San Diego, CA: Academic Press; 1992.
Luo, G., Santoro, I.M., McDaniel, L.D., Nishijima, I., Mills, M., Youssoufian, H., Vogel, H., Schultz, R.A. & Bradley, A. (2000). Cancer predisposition caused by elevated mitotic recombination in Bloom mice. Nature Genetics, 26(4), 424-429. https://doi.org/ 10.1038/82548.
Mendis, J. C., Tennakoon, T. K., & Jayasinghe, C. D. (2018). Zebrafish embryo toxicity of a binary mixture of pyrethroid insecticides: d-tetramethrin and cyphenothrin. Journal of Toxicology, 2018, 4182694. https://doi.org/10.1155/2018/4182694
Mukhopadhyay, I., Chowdhuri, D. K., Bajpayee, M., & Dhawan, A. (2004). Evaluation of in vivo genotoxicity of cypermethrin in Drosophila melanogaster using the alkaline Comet assay. Mutagenesis, 19(2), 85–90. https://doi.org/10.1093/ mutage/geh007
Mukhopadhyay, I., Siddique, H. R., Bajpai, V. K., Saxena, D. K., & Chowdhuri, D. K. (2006). Synthetic pyrethroid cypermethrin induced cellular damage in reproductive tissues of Drosophila melanogaster: Hsp70 as a marker of cellular damage. Archives of environmental contamination and toxicology, 51(4), 673–680. https://doi.org/ 10.1007/ s00244-005-0169-6
Nozawa, H., Minakata, K., Hasegawa, K., Yamagishi, I., Suzuki, M., Kitamoto, T., Watanabe, K. & Suzuki, O. (2021). A fatal case involved in pyrethroid insecticide ingestion: Quantification of tetramethrin and resmethrin in body fluids of a deceased by LC–MS/MS. Forensic Toxicology, 40, 189-198. https://doi.org/10.1007/s11419-021-00594-7.
Official Journal of the European Union (EU). (2018). Commission Regulation 2018/1480; 2018.
Ormerod, K.G., LePine, O.K., Abbineni, P.S., Bridgeman, J.M., Coorssen, J.R., Mercier, A.J. & Tattersall, G.J. (2017). Drosophila development, physiology, behaviour, and lifespan are influenced by altered dietary composition. Fly, 11(3), 153–170. https://doi.org/10.1080/19336934.2017.1304331.
Orsolin, P.C., Silva-Oliveira, R.G. & Nepomuceno, J.C. (2012). Assessment of the mutagenic, recombinagenic and carcinogenic potential of orlistat in somatic cells of Drosophila melanogaster. Food and Chemical Toxicology, 50, 2598–2604. https://doi.org/10.1016/j.fct.2012.05.008.
Pandey, U.B. & Nichols, C.D. (2011). Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacological Reviews, 63(2), 411–436. https://doi.org/10.1124/pr.110.003293.
Parimi, D., Sundararajan, V., Sadak, O., Gunasekaran, S., Mohideen, S.S. & Sundaramurthy, A. (2019). Synthesis of positively and negatively charged CeO2 nanoparticles: Investigation of the role of surface charge on growth and development of Drosophila melanogaster. ACS Omega, 4(1), 104−113. https://doi.org/10.1021/ acsomega.8b02747.
QYResearch Group, (2021). Global Synthetic Pyrethroids Market Growth 2021-2026. [cited 2022 Dec 24]. Available from: https://www. marketresearch.com/LP-Information-Inc-v4134/ Global-Synthetic-Pyrethroids-Growth-14812096/
Reiter, L.T., Potocki, L., Chien, S., Gribskov, M. & Bier, E. (2001). A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Research, 11(6), 1114-25. https://doi.org/10.1101/gr.169101.
Saillenfait, A.M., Ndiaye, D. & Sabate, JP. (2015). Pyrethroids: Exposure and health effects – An update. International Journal of Hygiene and Environmental Health, 218(3), 281-292. https://doi.org/10.1016/j.ijheh.2015.01.002.
Sanchez-Alarcon, J., Milic, M., Arroyo, S.G., Goncalez, J.M.R.M. & Valencia, R. (2016). Assessment of DNA damage by Comet assay in buccal epithelial cells: Problems, achievement, perspectives. Environmental Health Risk - Hazardous Factors to Living Species, 77-135. https://doi.org/ 10.5772/ 62760.
Shashikumar, S., & Rajini, P. S. (2010). Cypermethrin elicited responses in heat shock protein and feeding in Caenorhabditis elegans. Ecotoxicology and environmental safety, 73(5), 1057–1062. https://doi.org/10.1016/j.ecoenv.2010.02.003
Shen, P., Hsieh, T. H., Yue, Y., Sun, Q., Clark, J. M., & Park, Y. (2017). Deltamethrin increases the fat accumulation in 3T3-L1 adipocytes and Caenorhabditis elegans. Food and chemical toxicology, 101, 149–156. https://doi.org/ 10.1016/j.fct.2017.01.015
Sierra, L.M., Carmona, E.R., Aguado, L. & Marcos, R. (2014). The Comet assay in Drosophila: Neuroblast and hemocyte cells. In: L.M. Sierra, & I. Gaivao (Eds.), Genotoxicity and DNA repair: A practical approach, methods in pharmacology and toxicology. Springer Science+Business Media, New York, p. 269-282. https://doi.org/10.1007/978-1-4939-1068-7_15.
Simaremare, S.R.S., Hung, C.C., Yu, T.H., Hsieh, C.J. & Yiin, L.M. (2021). Association between pesticides in house dust and residential proximity to farmland in a rural region of Taiwan. Toxics, 9(8), 180. https://doi.org/10.3390/toxics9080180.
Singh, P., Lata, P., Patel, S., Pandey, A. K., Jain, S. K., Shanker, R., & Dhawan, A. (2011). Expression profiling of toxicity pathway genes by real-time PCR array in cypermethrin-exposed mouse brain. Toxicology mechanisms and methods, 21(3), 193–199. https://doi.org/10.3109/15376516.2010.538939
Siudeja, K. & Bardin, A.J. (2017). Somatic recombination in adult tissues: What is there to learn? Fly, 11(2), 121-128. https://doi.org/ 10.1080/19336934.2016.1249073.
Szabad, J., Soos, I., Polgar, G. & Hejja, G. (1983). Testing the mutagenicity of malondialdehyde and formaldehyde by the Drosophila mosaic and the sex-linked recessive lethal tests. Mutation Research, 113(2), 117-133. https://doi.org/ 10.1016/0165-1161(83)90224-8.
Tasman, K., Rands, S.A. & Hodge, J.J.L. (2021). The power of Drosophila melanogaster for modeling neonicotinoid effects on pollinators and identifying novel mechanisms. Frontiers in Physiology, 12, 659440. https://doi.org/10.3389/fphys.2021.659440.
United States Environmental Protection Agency (US EPA). (2010). Reregistration Eligibility Decision (RED) Document for Tetramethrin. Prevention, Pesticides and Toxic Substances. EPA 738-R-08-012; 2010.
United States Environmental Protection Agency (US EPA). (2016). Washington, D.C. 20460, Office of Chemical Safety and Pollution Prevention. Preliminary Comparative Environmental Fate and Ecological Risk Assessment for the Registration Review of Eight Synthetic Pyrethroids and Pyrethrins DP No. D425791; 2016.
United States Environmental Protection Agency (US EPA). (2019). Washington, D.C. 20460, Office of Chemical Safety and Pollution Prevention. Tetramethrin Updated Human Health Risk Assessment. DP No. 453657; 2019.
United States Environmental Protection Agency (US EPA). (2020). Tetramethrin. Interim Registration Review Decision, Case Number 2660; 2020.
Wang, W., Warren, M. & Bradley, A. (2007). Induced mitotic recombination of p53 in vivo. Proceedings of the National Academy of Sciences of the United States of America, 104(11), 4501–4505. https://doi.org/10.1073/pnas.0607953104
Würgler, F.E. & Vogel, E.W. (1986). In vivo mutagenicity testing using somatic cells of Drosophila melanogaster. In: F.J. de Serres (Ed.), Chemical Mutagens, Vol. 10, Plenum, New York, p. 1-72.
Yan, Y., Yang, Y., You, J., Yang, G., Xu, Y., Huang, N., Wang, X., Ran, D., Yuan, X., Jin, Y., Fan, Y., Lei, J., Li, W., & Gu, H. (2011). Permethrin modulates cholinergic mini-synaptic currents by partially blocking the calcium channel. Toxicology letters, 201(3), 258–263. https://doi.org/10.1016/j.toxlet. 2011.01.009
Yavuz, O., Aksoy, A., Das, Y. K., Gulbahar, M. Y., Guvenc, D., Atmaca, E., Yarim, F. G., & Cenesiz, M. (2015). Subacute oral toxicity of combinations of selected synthetic pyrethroids, piperonyl butoxide, and tetramethrin in rats. Toxicology and industrial health, 31(4), 289–297. https://doi.org/ 10.1177/ 0748233712469651
Yavuz, O., Aksoy, A., Das, Y. K., Gulbahar, M. Y., Yarim, G. F., Cenesiz, M., Atmaca, E., & Guvenc, D. (2010). Repeated-dose 14-day dermal toxicity of different combinations of some synthetic pyrethroid insecticides, piperonyl butoxide, and tetramethrin in rats. Cutaneous and ocular toxicology, 29(1), 16–25. https://doi.org/10.3109/15569520903415076
Yuan, L., Lin, J., Xu, Y., Peng, Y., Clark, J. M., Gao, R., Park, Y., & Sun, Q. (2019). Deltamethrin promotes adipogenesis via AMPKα and ER stress-mediated pathway in 3T3- L1 adipocytes and Caenorhabditis elegans. Food and chemical toxicology, 134, 110791. https://doi.org/ 10.1016/j.fct.2019.110791
Zaller, J.G. & Brühl, C.A. (2019). Editorial: Non-target effects of pesticides on organisms inhabiting agroecosystems. Frontiers in Environmental Science, 7, 75. https://doi.org/10.3389/fenvs. 2019.00075.
Zhang, D., Park, Z.Y., Park, J.A., Kim, S.K., Jeong, D., Cho, S.H., Shim, J.H., Kim, J.S., El-Aty, A.M. & Shin, H.C. (2016). A combined liquid chromatography-triple-quadrupole mass spectrometry method for the residual detection of veterinary drugs in porcine muscle, milk, and eggs. Environmental Monitoring and Assessment, 188(6), 348. https://doi.org/10.1007/s10661-016-5344-x.
Zhong, M., Zhai, Q., Zhang, R., Yin, H., Li, J., Ma, Z., Fang, L., Zhang, C., & Li, Y. (2021). Effect of pyrethroid pesticides on the testis of male rats: A meta-analysis. Toxicology and industrial health, 37(4), 229–239. https://doi.org/10.1177/074823372 11000979
Zordan, M., Osti, M., Pesce, M. & Costa, R. (1994). Chloral hydrate is recombinogenic in the wing spot test in Drosophila melanogaster. Mutation Research, 322(2), 111-116. https://doi.org/10.1016/ 0165-1218(94)00017-4.

Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Burcin Yalcin
0000-0002-9694-5839
Türkiye

Merve Güneş
0000-0003-3278-0542
Türkiye

Ayşen Yağmur Kurşun
0000-0003-1657-6808
Türkiye

Ghada Tagorti
0000-0003-4597-8320
Türkiye

Ezgi Golal
0000-0002-7685-7479
Türkiye

Bülent Kaya ^*
0000-0002-0491-9781
Türkiye

Early Pub Date

January 21, 2024

Publication Date

April 1, 2024

Submission Date

January 3, 2023

Acceptance Date

September 7, 2023

Published in Issue

Year 2024 Volume: 27 Number: 2

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1224968

IZ

https://izlik.org/JA36BP97LH

Cite

RIS / Bibtex

APA

Yalcin, B., Güneş, M., Kurşun, A. Y., Tagorti, G., Golal, E., & Kaya, B. (2024). Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 27(2), 304-315. https://doi.org/10.18016/ksutarimdoga.vi.1224968

AMA

1.Yalcin B, Güneş M, Kurşun AY, Tagorti G, Golal E, Kaya B. Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. KSU J. Agric Nat. 2024;27(2):304-315. doi:10.18016/ksutarimdoga.vi.1224968

Chicago

Yalcin, Burcin, Merve Güneş, Ayşen Yağmur Kurşun, Ghada Tagorti, Ezgi Golal, and Bülent Kaya. 2024. “Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi 27 (2): 304-15. https://doi.org/10.18016/ksutarimdoga.vi.1224968.

EndNote

Yalcin B, Güneş M, Kurşun AY, Tagorti G, Golal E, Kaya B (April 1, 2024) Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 27 2 304–315.

IEEE

[1]B. Yalcin, M. Güneş, A. Y. Kurşun, G. Tagorti, E. Golal, and B. Kaya, “Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster”, KSU J. Agric Nat., vol. 27, no. 2, pp. 304–315, Apr. 2024, doi: 10.18016/ksutarimdoga.vi.1224968.

ISNAD

Yalcin, Burcin - Güneş, Merve - Kurşun, Ayşen Yağmur - Tagorti, Ghada - Golal, Ezgi - Kaya, Bülent. “Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 27/2 (April 1, 2024): 304-315. https://doi.org/10.18016/ksutarimdoga.vi.1224968.

JAMA

1.Yalcin B, Güneş M, Kurşun AY, Tagorti G, Golal E, Kaya B. Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. KSU J. Agric Nat. 2024;27:304–315.

MLA

Yalcin, Burcin, et al. “Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila Melanogaster”. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, vol. 27, no. 2, Apr. 2024, pp. 304-15, doi:10.18016/ksutarimdoga.vi.1224968.

Vancouver

1.Burcin Yalcin, Merve Güneş, Ayşen Yağmur Kurşun, Ghada Tagorti, Ezgi Golal, Bülent Kaya. Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. KSU J. Agric Nat. 2024 Apr. 1;27(2):304-15. doi:10.18016/ksutarimdoga.vi.1224968

Cited By

Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi

https://doi.org/10.18016/ksutarimdoga.vi.1574067