Antioxidant Properties of Methanolic Extract of Sigesbeckia orientalis L. from Rize

Mehtap Atak; Zeynep Bakan; Eda Yılmaz Kutlu; Merve Hüner Yiğit; Nebahat Ejder

doi:10.18016/ksutarimdoga.vi.1491528

TR EN

Rize Yöresinde Yetişen Sigesbeckia orientalis L. Metanollü Ekstresinin Antioksidan Özellikleri

Öz

Sigesbeckiae orientalis Linnaeus, uzun yıllardır enflamatuvar hastalıkların tedavisinde kullanılan geleneksel bir bitkisel ilaçtır. Sigesbeckiae cinsine ait üç türü bulunmaktadır: Sigesbeckia. pubescens Markino (SP), Sigesbeckia glabrescens Makino (SG) ve Sigesbeckia orientalis L. (SO). S. orientalis doğu tıbbında romatizmal rahatsızlıkları hafifletmek, eklemlerin hareketliliğini iyileştirmek ve toksisiteye karşı koruma sağlamak için kullanılmıştır. Bu bitki Çin, Filipinler ve Vietnam gibi Asya ülkelerinde doğal olarak yetişmektedir. Türkiye’de özellikle Karadeniz Bölgesinde yetişen S. orientalis Sarıteçan olarak adlandırılmaktadır. Bu çalışmada, S. orientalis’in metanollü ekstresinin antioksidan kapasitesi toplam fenolik madde miktarı (TPMA) ve toplam flavonoid miktarı (TFA) belirlenerek, antioksidan aktivitesi Ferrik İndirgeyici Antioksidan Güç (FRAP), Cu (II) İyonu İndirgeyici Antioksidan Kapasite (CUPRAC) ve 2,2-difenil-1-pikrilhidrazil Serbest Radikalleri Temizleme Kapasitesi (DPPH) analizleri yapılarak değerlendirildi. S. orientalis ekstresinin toplam fenolik madde miktarı (TPMA) 18 ± 0.57 mgGAE/g kuru ağırlık olarak belirlenirken toplam flavonoid miktarı (TFA) ise 8.55±0.21 mg QE/g kuru ağırlık olarak belirlendi. DPPH (SC50) 380±12 µg/mL bulunurken CUPRAC ve FRAP aktiviteleri sırasıyla 74 ± 1.99 ve 19 ±1.38 mg TE/g kuru ağırlık bulundu. Bu sonuçlar, Rize İkizdere bölgesinde yetişen S. orientalis bitkisinin güçlü antioksidan özelliklere sahip olduğunu ortaya koymaktadır. Bu nedenle, S. orientalis bitkisi, geleneksel tıbbın ötesinde modern tamamlayıcı tıpta da araştırılmaya değer bir potansiyele sahip olabilir.

Anahtar Kelimeler

Antioxidant Properties of Methanolic Extract of Sigesbeckia orientalis L. from Rize

Abstract

Sigesbeckia orientalis Linnaeus is a traditional herbal medicine that has been used for many years to treat inflammatory diseases. The genus Sigesbeckia comprises three species: Sigesbeckia pubescens Markino (SP), Sigesbeckia glabrescens Makino (SG), and Sigesbeckia orientalis L. (SO). S. orientalis has been used in Eastern medicine to alleviate rheumatic disorders, improve joint mobility, and provide protection against toxicity. This plant is naturally found in countries such as China, the Philippines, and Vietnam. In Türkiye, particularly in the Black Sea region, S. orientalis is known as Sarıteçan. In this study, the antioxidant capacity of the methanolic extract of S. orientalis was evaluated by determining the total phenolic content (TPMC) and total flavonoid content (TFC). The antioxidant activity was assessed using Ferric Reducing Antioxidant Power (FRAP), Cu (II) Ion Reducing Antioxidant Capacity (CUPRAC), and 2,2-Diphenyl-1-picrylhydrazyl Free Radical Scavenging Capacity (DPPH) assays. The total phenolic content (TPMC) of S. orientalis extract was determined to be 18 ± 0.57 mgGAE/g dry weight, and the total flavonoid content (TFC) was 8.55 ± 0.21 mg QE/g dry weight. The DPPH (SC50) was found to be 380 ± 12 µg/mL, while the CUPRAC and FRAP activities were 74 ± 1.99 and 19 ± 1.38 mg TE/g dry weight, respectively. These results demonstrate that S. orientalis grown in the Rize İkizdere region possesses strong antioxidant properties. Therefore, S. orientalis may have significant potential not only in traditional medicine but also in modern complementary medicine.

Keywords

Supporting Institution

Herhangi bir kurum yada kuruluştan destek alınmamıştır.

Ethical Statement

Etik kurula ihtiyaç bulunmamaktadır.

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Details

Primary Language

English

Subjects

Pharmaceutical Botany

Journal Section

Research Article

Authors

Mehtap Atak ^*
0000-0002-9451-906X
Türkiye

Zeynep Bakan
0009-0001-7567-2544
Türkiye

Eda Yılmaz Kutlu
0000-0003-1211-4964
Türkiye

Merve Hüner Yiğit
0000-0001-8988-4321
Türkiye

Nebahat Ejder
0000-0001-9557-2033
Türkiye

Early Pub Date

June 10, 2025

Publication Date

July 4, 2025

Submission Date

June 3, 2024

Acceptance Date

April 17, 2025

Published in Issue

Year 2025 Volume: 28 Number: 4

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1491528

IZ

https://izlik.org/JA96JE87BG

Cite

RIS / Bibtex

APA

Atak, M., Bakan, Z., Yılmaz Kutlu, E., Hüner Yiğit, M., & Ejder, N. (2025). Antioxidant Properties of Methanolic Extract of Sigesbeckia orientalis L. from Rize. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 28(4), 1095-1102. https://doi.org/10.18016/ksutarimdoga.vi.1491528