Chemical Content and Biological Activity Spectrum of Nigella sativa Seed Oil
Abstract
In this study, it was aimed
to investigate the chemical composition and biological activities including
antioxidant, anticholinesterase, antimicrobial and urease activity of Nigella sativa seed oil growing in Muğla
(Köyceğiz). The oil of plant was obtained using Soxhlet apparatus. Thirty-one
components of the oil were determined by Gas Chromatography-Mass Spectrometry
(GC-MS). The major components of oil were detected as palmitic acid (10.48%),
linoleic acid (8.05%), o-cyemene
(7.11%), 3,5-dimethyl cyclohexanol (6.68%), thymoquinone (6.44%), p-tert-buthyl catechol (6.28%) and
8-methyl-1-undecene (3.28%). The findings obtained from biological activity
assays showed that Nigella sativa oil
was a promising candidate that can be used in the discovery of new drugs and
the preparation of new natural drug preparations.
Keywords
Supporting Institution
Project Number
Thanks
References
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Details
Primary Language
English
Subjects
Structural Biology
Journal Section
Research Article
Authors
Yusuf Sıcak
*
0000-0003-2339-5837
Türkiye
Publication Date
December 31, 2019
Submission Date
March 9, 2019
Acceptance Date
May 16, 2019
Published in Issue
Year 2019 Volume: 22 Number: 6
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