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Total Bioactive Contents and Radical Scavenging Activities of Some Ruta L. Extracts

Yıl 2019, Cilt: 22 Sayı: 2, 193 - 201, 30.04.2019

Cennet Yaman , Deniz Ulukuş , Osman Tugay

https://doi.org/10.18016/ksutarimdoga.vi.486352
Cited By: 2

Öz

is
a genus of the Rutaceae family, mostly used as a traditional medicinal plant.
In this study, the antioxidant activities of methanolic and ethanolic extracts
of wild Ruta chalepensis L. (above
ground plant) and Ruta montana L.
(leaves-flowers, stems) were assessed. The results showed that methanol extract
of flower-leave of Ruta montana provided the highest yield of extraction (15.11%, 151.12±0.78
mg/g) whereas the lowest yield was
obtained in ethanol extract of stems of Ruta
montana (2.67%, 26.66±0.50 mg/g). Total flavonoid content in dry weight of
methanol and ethanol extracts of Ruta chalepensis
was found higher than other extracts except methanol leaves-flowers extract
of Ruta montana. It was determinated
that ethanol extracts of Ruta montana
stem sustained less total flavonoid and phenolic content. Also, radical
scavenging activities such as 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and
2,
2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS) of extracts
was investigated, and according to the solvent, it was revealed that extracts
of Ruta chalepensis exhibited high
activity. As a result, it has been discussed that Ruta can be used as a natural
antioxidant by taking advantage of these data. Ruta L.

Anahtar Kelimeler

Ruta L. flavonoids phenolics DPPH ABTS

Kaynakça

  • Aguilar-Santamaria L, Tortoriello J 1995. Anticonvulsant and sedative effects of crude extracts of Ternstroemia pringlei and Ruta chalepensis. Phytother Res, 10:531e3.
  • Ahn J, Grün IU, Mustapha A 2007. Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef. Food Microbiology, 24:7–14.
  • Al-Said MS, Tariq M, Al-Yahya MA, Rafatullah S, Ginnawi OT, Ageel AM 1990. Studies on Ruta chalepensis, an ancient medicinal herb still used in traditional medicine. J Ethnopharmaeol., 28:305–312.
  • Bajaj S, A. Urooj, Prabhasankar P 2006. Effect of incorporation of mint on texture, colour and sensory parameters of biscuits. International Journal of Food Properties, 9:691-700.
  • Bejar E, Bussmann R, Roa C, Sharon, D 1997. Herbs of Southern Ecuador. A Field Guide to the Medicinal Plants of Vilcabamba. Rodale Press, 256-257.
  • Boligon AA, Machado MM, Athayde ML 2014. Technical Evaluation of Antioxidant Activity. Medicinal chemistry, 4(7):517-522.
  • Caleja C, Barros L, Antonio AL, Ciric A, Barreira JCM, Soković M, ve ark., 2015.Development of a functional dairy food: Exploring bioactive and preservation effects of chamomile (Matricaria recutita L.). Journal of Functional Foods, 16:114-124.
  • Di Stasi LC, Hiruma CA, Guimaraes CM 1994. Medicinal plants used in Brazilian Amazon. Fitoterapia, 65:529–540.
  • El Guiche R, Tahrouch S, Amri O, El Mehrach K, Hatimie A 2015. Antioxidant activity and total phenolic and flavonoid contents of 30 medicinal and aromatic plants located in the South of Morocco. Int J New Technol Res., 1:7–11.
  • Ereifej, K.I., Feng, H., Rababah, T., Almajwal, A., Alủdatt,M., Gammoh, S.I., Oweis, L.I., 2015. Chemical composition, phenolics, anthocyanins concentration and antioxidant activity of ten wild edible plants. Food and Nutrition Sciences 6:581–590.
  • Fakhfakh N, Zouari S, Zouari M, Loussayef C, Zouari N 2012. Chemical composition of volatile compounds and antioxidant activities of essential oil, aqueous and ethanol extracts of wild Tunisian Ruta chalepensis L. (Rutacea). Journal of Medicinal Plant Research, 6:593–600.
  • Forment M, H Roques 1941. Répertoire desplantes médicinales et aromatiques d’Algérie. Ed. OFALAC, 59.
  • Gali L, Bedjou F 2018. Antioxidant and anticholinesterase effects of the ethanol extract, ethanol extract fractions and total alkaloids from the cultivated Ruta chalepensis, South African Journal of Botany, https://doi.org/10.1016/j.sajb.2018.04.011.
  • GangwarM, Gautam MK, Sharma AK, Tripathi YB, Goel RK, Nath G 2014. Antioxidant Capacity and Radical Scavenging Effect of Polyphenol Rich Mallotus philippenensis Fruit Extract on Human Erythrocytes: An In Vitro Study. ScientificWorldJournal., 12.
  • Gonzalez-Trujano ME, Carrera D, Ventura-Martinez R, Cedillo-Portugal E, Navarrete A 2006. Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice. J Ethnopharmacol., 106:129–135.
  • Günaydin K, Göycıncık S 2005. Phytochemical studies on Ruta chalepensİs (LAM.) lamarck. Natural Product Research, 19(3):203-10.
  • Iauk L, Mangano K, Rapisarda A, Ragusa S, Maiolino L, Musumeci R, Costanzo R, Serra A, Speciale A 2004. Protection against murine endotoxemia by treatment with Ruta chalepensis L., a plant with anti-inflammatory properties. J Ethnopharmacol., 90:267–272.
  • Jastrzebski Z, Medina OJ, Moreno LM, Gorinstein S 2007. In vitro studies of polyphenol compounds, total antioxidant capacity and other dietary indices in a mixture of plants (Prolipid). International Journal of Food Sciences and Nutrition, 58:531–541.
  • Kacem M, Kacem I, Simon G, BenMansour A, Chaabouni S, Elfeki A, Bouaziz M 2015. Phytochemicals and biological activities of Ruta chalepensis L. growing in Tunisia. Food Bioscience, 12:73–83.
  • Kacem M, Simon G, Leschiera R, Misery L, ElFeki A, Lebonvallet N 2014. Antioxidant and anti-inflammatory effects of Ruta chalepensis L. extracts on LPS-stimulated RAW 264.7 cells. In Vitro Cell Dev Biol Anim., 51:128–141.
  • Katalinic V, Milos M, Kulisic T, Jukic M 2006. Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols. Food Chemistry, 94:550–557.
  • Kettawan A, Chanlekha K, Kongkachuichai R, Charoensiri R 2011. Effect of cooking on antioxidant activities and polyphenol content of edible mushrooms commonly consumed in Thailand. Pakistan Journal of Nutrition, 10:1094–1103.
  • Khadhri A, Bouali I, Belkhir S, Mokded R, Smiti S, Falé P, Eduarda M, Araújo M, Luisa M, Serralheiro M 2017. Invitro digestion, antioxidant and antiacetylcholinesterase activities of two species of Ruta: Ruta chalepensis and Ruta montana. Pharmaceutical Biology, 55(1):101-107.
  • Kubitzki K, Kallunki JA, Duretto M, Wilson PG 2011. Rutaceae. In: Kubitzki, K. (Ed) The families and genera of vascular plants. Vol. 10, Springer Verlag, Berlin, 276–356.
  • Khlifi D, Sghaier RM, Amouri S, Laouini D, Hamdi M, Bouajila J 2013. Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L. Food Chem Toxicol., 55:202–208.
  • Li P, Sun W, Luo C, Shan T, Mou Y, Lu S, Mao Z, Zhou L 2012. In vitro evaluation of antioxidant activities of polysaccharides from the endophytic fungus Berkleasmium sp. Dzf12. African Journal of Microbiology Research 6:471–477.
  • Loizzo MR, Falco T, Bonesi M, Sicari V, Tundis R, Bruno M 2018. Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities. Natural Product Research, 32(5):521–528.
  • Mansour SS, Tarik MY, Rafatullah MAS, Ginnawi OT, Ageel AM 1990. Studies on Ruta chalepensis, an ancient medicinal herb still used in traditional medicine. J Ethnopharmacol., 28:305–312.
  • Martínez-Pérez EF, Hernández-TeránF, Serrano-GallardoLB 2017. In Vıvo Effect Of Ruta chalepensıs extract On Hepatıc Cytochrome 3A1 In Rats. Afr J Tradit Complement Altern Med., 14(4):62–68.
  • Morton CM, Telmer C 2014. New Subfamily Classification for the Rutaceae. Annals of the Missouri Botanical Garden, 99(4):620-641.
  • Narayanasamy B, Jeyakumar N, Manoharan DK 2018. Effect of natural antioxidants on the oxidation stability of methyl ester of rubber seed oil. Journal Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, 40 (6):680-687.
  • Ouerghemmi I, Rebey IB, Rahali FZ, Bourgou S, Pistelli L, Ksouri R, Marzouk B, TounsiMS 2017. Antioxidant and antimicrobial phenolic compounds from extracts of cultivated and wild-grown Tunisian Ruta chalepensis. Journal of Food and Drug Analysis, 25(2):350-359.
  • Park JH, Lee HS 2015. Inhibitory effects of quinoline isolated from Ruta chalepensis and its structurally related derivatives against α-amylase or α-glucosidase. J Appl Biol Chem., 58:5–8.
  • Pasqualone A, Bianco AM, Paradiso VM, Summo C, Gambacorta G, Caponio F. ve ark., 2015. Production and characterization of functional biscuits obtained from purple wheat. Food Chemistry, 180:64-70.
  • Perry LM 1980. Medicinal Plants of East and Southeast Asia. The MIT Press, Boston, MA, pp. 368.
  • Pollio A, De Natale A, Appetiti E, Aliotta G, Touwaide A 2008. Continuity and change in the Mediterranean medical tradition: Ruta spp. (Rutaceae) in Hippocratic medicine and present practices. J Ethnopharmacol., 116:469–482.
  • Ramesh BN, Rao TSS, Prakasam A, Sambamurti K, Rao KSJ 2013. Neuronutrition and Alzheimer's disease. Journal of Alzheimer's Disease, 19:1123–1139.
  • Salvo G, Ho SYW, Rosenbaum G, Ree R, Conti E 2010. Tracing the temporal and spatial origins of island endemics in the Mediterranean region: a case study from the citrus family (Ruta L., Rutaceae). Systematic Biology, 59:705–722.
  • Shah MA, Don Bosco SJ, Mir SA 2014. Plant extracts as natural antioxidants in meat and meat products. Meat Science, 98, pp. 21-33.
  • Townsend CC 1967. Haplophyllum A.Juss. In: Davis, P.H (Ed.) Flora of Turkey and The Aegean Islands, vol 2. Edinburgh University Press, Edinburgh, pp 496–506.
  • Tugay O 2012. Rutaceae. Şu eserde: Güner, A., Aslan, S., Ekim, T., Vural, M., Babaç, M. T., (edlr.) Türkiye Bitkileri Listesi (Damarlı Bitkiler). NezahatGökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını. İstanbul.
  • Turgay O, Ulukuş D 2017. Haplophyllum sahinii(Rutaceae), a new species from Central Anatolia (Turkey).Phytotaxa, 29(3):265–272.
  • Ulubelen A, Ertugrul L, Birman H, Yigit R, Erseven G, Olgac V 1994. Antifertility effects of some coumarins isolated from Ruta chalepensis and R. chalepensis var. latifolia in rodents. Phytother Res., 8:233–236.
  • Zellagui A, Belkassam A, Belaidi A, Gherraf N 2012. Environmental impact on the Chemical Composition and yield of essential oils of Algerian Ruta Montana (Clus.) L and their antioxidant and antibacterial activities. Advances in Environmental Biology, 6 (10):2684-2688.

Bazı Ruta L. Ekstraktlarının Biyoaktif Madde İçerikleri ve Radikal Kovucu Aktiviteleri

Yıl 2019, Cilt: 22 Sayı: 2, 193 - 201, 30.04.2019

Cennet Yaman , Deniz Ulukuş , Osman Tugay

https://doi.org/10.18016/ksutarimdoga.vi.486352
Cited By: 2

Öz

Ruta L. geleneksel tıbbi bitki
olarak yaygın kullanılan, Rutaceae familyasının cinslerinden biridir. Bu
çalışmada, yabani Ruta chalepensis L.
(toprak üstü kısmı) ve Ruta montana L.
(yaprak-çiçek ve gövde kısımları) türlerinin metanol ve etanol ekstraktlarının
antioksidan aktiviteleri incelenmiştir. 
En yüksek ekstraktsiyon verimini R.
montana  (çiçek-yaprak) metanol
ekstraktı sağlamıştır (% 15.11, 151.12 ± 0.78 mg / g). En düşük verim ise R. montana (gövde) etanol ekstraktında
(% 2.67, 26.66 ± 0.50 mg / g) tespit edilmiştir. R. chalepensis metanol ve etanol ekstraktlarının kuru madde
içerisindeki toplam flavonoid madde içeriğinin, R. montana  metanol
çiçek-yaprak ekstraktı hariç diğer ekstraktlarından daha yüksek olduğu
gözlenmiştir. Toplam flavonoid ve fenolik madde içeriği en az R. montana gövde kısmının etanol
ekstraktlarından elde edilmiştir. Ayrıca ekstraktların
2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) ve 2, 2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS) gibi
radikal süpürücü aktiviteleri araştırılmış ve çözücü bazında
değerlendirildiğinde R. chalepensis  ekstraktlarının daha yüksek aktivite
sergilediği gözlenmiştir. Sonuç olarak, bu çalışmada elde edilen verilerden
yararlanılarak Ruta ekstraktlarının
doğal bir antioksidan kaynağı olabilirliliği tartışılmıştır.

Anahtar Kelimeler

Ruta L. flavonoid fenolik DPPH ABTS

Kaynakça

  • Aguilar-Santamaria L, Tortoriello J 1995. Anticonvulsant and sedative effects of crude extracts of Ternstroemia pringlei and Ruta chalepensis. Phytother Res, 10:531e3.
  • Ahn J, Grün IU, Mustapha A 2007. Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef. Food Microbiology, 24:7–14.
  • Al-Said MS, Tariq M, Al-Yahya MA, Rafatullah S, Ginnawi OT, Ageel AM 1990. Studies on Ruta chalepensis, an ancient medicinal herb still used in traditional medicine. J Ethnopharmaeol., 28:305–312.
  • Bajaj S, A. Urooj, Prabhasankar P 2006. Effect of incorporation of mint on texture, colour and sensory parameters of biscuits. International Journal of Food Properties, 9:691-700.
  • Bejar E, Bussmann R, Roa C, Sharon, D 1997. Herbs of Southern Ecuador. A Field Guide to the Medicinal Plants of Vilcabamba. Rodale Press, 256-257.
  • Boligon AA, Machado MM, Athayde ML 2014. Technical Evaluation of Antioxidant Activity. Medicinal chemistry, 4(7):517-522.
  • Caleja C, Barros L, Antonio AL, Ciric A, Barreira JCM, Soković M, ve ark., 2015.Development of a functional dairy food: Exploring bioactive and preservation effects of chamomile (Matricaria recutita L.). Journal of Functional Foods, 16:114-124.
  • Di Stasi LC, Hiruma CA, Guimaraes CM 1994. Medicinal plants used in Brazilian Amazon. Fitoterapia, 65:529–540.
  • El Guiche R, Tahrouch S, Amri O, El Mehrach K, Hatimie A 2015. Antioxidant activity and total phenolic and flavonoid contents of 30 medicinal and aromatic plants located in the South of Morocco. Int J New Technol Res., 1:7–11.
  • Ereifej, K.I., Feng, H., Rababah, T., Almajwal, A., Alủdatt,M., Gammoh, S.I., Oweis, L.I., 2015. Chemical composition, phenolics, anthocyanins concentration and antioxidant activity of ten wild edible plants. Food and Nutrition Sciences 6:581–590.
  • Fakhfakh N, Zouari S, Zouari M, Loussayef C, Zouari N 2012. Chemical composition of volatile compounds and antioxidant activities of essential oil, aqueous and ethanol extracts of wild Tunisian Ruta chalepensis L. (Rutacea). Journal of Medicinal Plant Research, 6:593–600.
  • Forment M, H Roques 1941. Répertoire desplantes médicinales et aromatiques d’Algérie. Ed. OFALAC, 59.
  • Gali L, Bedjou F 2018. Antioxidant and anticholinesterase effects of the ethanol extract, ethanol extract fractions and total alkaloids from the cultivated Ruta chalepensis, South African Journal of Botany, https://doi.org/10.1016/j.sajb.2018.04.011.
  • GangwarM, Gautam MK, Sharma AK, Tripathi YB, Goel RK, Nath G 2014. Antioxidant Capacity and Radical Scavenging Effect of Polyphenol Rich Mallotus philippenensis Fruit Extract on Human Erythrocytes: An In Vitro Study. ScientificWorldJournal., 12.
  • Gonzalez-Trujano ME, Carrera D, Ventura-Martinez R, Cedillo-Portugal E, Navarrete A 2006. Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice. J Ethnopharmacol., 106:129–135.
  • Günaydin K, Göycıncık S 2005. Phytochemical studies on Ruta chalepensİs (LAM.) lamarck. Natural Product Research, 19(3):203-10.
  • Iauk L, Mangano K, Rapisarda A, Ragusa S, Maiolino L, Musumeci R, Costanzo R, Serra A, Speciale A 2004. Protection against murine endotoxemia by treatment with Ruta chalepensis L., a plant with anti-inflammatory properties. J Ethnopharmacol., 90:267–272.
  • Jastrzebski Z, Medina OJ, Moreno LM, Gorinstein S 2007. In vitro studies of polyphenol compounds, total antioxidant capacity and other dietary indices in a mixture of plants (Prolipid). International Journal of Food Sciences and Nutrition, 58:531–541.
  • Kacem M, Kacem I, Simon G, BenMansour A, Chaabouni S, Elfeki A, Bouaziz M 2015. Phytochemicals and biological activities of Ruta chalepensis L. growing in Tunisia. Food Bioscience, 12:73–83.
  • Kacem M, Simon G, Leschiera R, Misery L, ElFeki A, Lebonvallet N 2014. Antioxidant and anti-inflammatory effects of Ruta chalepensis L. extracts on LPS-stimulated RAW 264.7 cells. In Vitro Cell Dev Biol Anim., 51:128–141.
  • Katalinic V, Milos M, Kulisic T, Jukic M 2006. Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols. Food Chemistry, 94:550–557.
  • Kettawan A, Chanlekha K, Kongkachuichai R, Charoensiri R 2011. Effect of cooking on antioxidant activities and polyphenol content of edible mushrooms commonly consumed in Thailand. Pakistan Journal of Nutrition, 10:1094–1103.
  • Khadhri A, Bouali I, Belkhir S, Mokded R, Smiti S, Falé P, Eduarda M, Araújo M, Luisa M, Serralheiro M 2017. Invitro digestion, antioxidant and antiacetylcholinesterase activities of two species of Ruta: Ruta chalepensis and Ruta montana. Pharmaceutical Biology, 55(1):101-107.
  • Kubitzki K, Kallunki JA, Duretto M, Wilson PG 2011. Rutaceae. In: Kubitzki, K. (Ed) The families and genera of vascular plants. Vol. 10, Springer Verlag, Berlin, 276–356.
  • Khlifi D, Sghaier RM, Amouri S, Laouini D, Hamdi M, Bouajila J 2013. Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L. Food Chem Toxicol., 55:202–208.
  • Li P, Sun W, Luo C, Shan T, Mou Y, Lu S, Mao Z, Zhou L 2012. In vitro evaluation of antioxidant activities of polysaccharides from the endophytic fungus Berkleasmium sp. Dzf12. African Journal of Microbiology Research 6:471–477.
  • Loizzo MR, Falco T, Bonesi M, Sicari V, Tundis R, Bruno M 2018. Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities. Natural Product Research, 32(5):521–528.
  • Mansour SS, Tarik MY, Rafatullah MAS, Ginnawi OT, Ageel AM 1990. Studies on Ruta chalepensis, an ancient medicinal herb still used in traditional medicine. J Ethnopharmacol., 28:305–312.
  • Martínez-Pérez EF, Hernández-TeránF, Serrano-GallardoLB 2017. In Vıvo Effect Of Ruta chalepensıs extract On Hepatıc Cytochrome 3A1 In Rats. Afr J Tradit Complement Altern Med., 14(4):62–68.
  • Morton CM, Telmer C 2014. New Subfamily Classification for the Rutaceae. Annals of the Missouri Botanical Garden, 99(4):620-641.
  • Narayanasamy B, Jeyakumar N, Manoharan DK 2018. Effect of natural antioxidants on the oxidation stability of methyl ester of rubber seed oil. Journal Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, 40 (6):680-687.
  • Ouerghemmi I, Rebey IB, Rahali FZ, Bourgou S, Pistelli L, Ksouri R, Marzouk B, TounsiMS 2017. Antioxidant and antimicrobial phenolic compounds from extracts of cultivated and wild-grown Tunisian Ruta chalepensis. Journal of Food and Drug Analysis, 25(2):350-359.
  • Park JH, Lee HS 2015. Inhibitory effects of quinoline isolated from Ruta chalepensis and its structurally related derivatives against α-amylase or α-glucosidase. J Appl Biol Chem., 58:5–8.
  • Pasqualone A, Bianco AM, Paradiso VM, Summo C, Gambacorta G, Caponio F. ve ark., 2015. Production and characterization of functional biscuits obtained from purple wheat. Food Chemistry, 180:64-70.
  • Perry LM 1980. Medicinal Plants of East and Southeast Asia. The MIT Press, Boston, MA, pp. 368.
  • Pollio A, De Natale A, Appetiti E, Aliotta G, Touwaide A 2008. Continuity and change in the Mediterranean medical tradition: Ruta spp. (Rutaceae) in Hippocratic medicine and present practices. J Ethnopharmacol., 116:469–482.
  • Ramesh BN, Rao TSS, Prakasam A, Sambamurti K, Rao KSJ 2013. Neuronutrition and Alzheimer's disease. Journal of Alzheimer's Disease, 19:1123–1139.
  • Salvo G, Ho SYW, Rosenbaum G, Ree R, Conti E 2010. Tracing the temporal and spatial origins of island endemics in the Mediterranean region: a case study from the citrus family (Ruta L., Rutaceae). Systematic Biology, 59:705–722.
  • Shah MA, Don Bosco SJ, Mir SA 2014. Plant extracts as natural antioxidants in meat and meat products. Meat Science, 98, pp. 21-33.
  • Townsend CC 1967. Haplophyllum A.Juss. In: Davis, P.H (Ed.) Flora of Turkey and The Aegean Islands, vol 2. Edinburgh University Press, Edinburgh, pp 496–506.
  • Tugay O 2012. Rutaceae. Şu eserde: Güner, A., Aslan, S., Ekim, T., Vural, M., Babaç, M. T., (edlr.) Türkiye Bitkileri Listesi (Damarlı Bitkiler). NezahatGökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını. İstanbul.
  • Turgay O, Ulukuş D 2017. Haplophyllum sahinii(Rutaceae), a new species from Central Anatolia (Turkey).Phytotaxa, 29(3):265–272.
  • Ulubelen A, Ertugrul L, Birman H, Yigit R, Erseven G, Olgac V 1994. Antifertility effects of some coumarins isolated from Ruta chalepensis and R. chalepensis var. latifolia in rodents. Phytother Res., 8:233–236.
  • Zellagui A, Belkassam A, Belaidi A, Gherraf N 2012. Environmental impact on the Chemical Composition and yield of essential oils of Algerian Ruta Montana (Clus.) L and their antioxidant and antibacterial activities. Advances in Environmental Biology, 6 (10):2684-2688.
Toplam 44 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm ARAŞTIRMA MAKALESİ (Research Article)
Yazarlar

Cennet Yaman 0000-0002-2364-8171

Deniz Ulukuş 0000-0002-9627-5492

Osman Tugay 0000-0003-3980-7648

Yayımlanma Tarihi 30 Nisan 2019
Gönderilme Tarihi 21 Kasım 2018
Kabul Tarihi 2 Ocak 2019
Yayımlandığı Sayı Yıl 2019Cilt: 22 Sayı: 2

Kaynak Göster

APA Yaman, C., Ulukuş, D., & Tugay, O. (2019). Bazı Ruta L. Ekstraktlarının Biyoaktif Madde İçerikleri ve Radikal Kovucu Aktiviteleri. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi, 22(2), 193-201. https://doi.org/10.18016/ksutarimdoga.vi.486352

Cited By

Radical Scavenging and Antibacterial Activities of Ruta buxbaumii Poir. (Rutaceae) Growing in Raman Mountain-Batman
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
https://doi.org/10.16984/saufenbilder.898031
Dekoksiyon tıbbi adaçayı ve oğul otu çaylarının fitokimyasalları ve antioksidan aktiviteleri üzerine örnek miktarı ve dekoksiyon süresinin etkisi
Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi
Cennet YAMAN
https://doi.org/10.18016/ksutarimdoga.vi.810689
 Kapak Resmi İndir

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