Year 2019, Volume 22 , Issue 2, Pages 193 - 201 2019-04-30

Bazı Ruta L. Ekstraktlarının Biyoaktif Madde İçerikleri ve Radikal Kovucu Aktiviteleri
Total Bioactive Contents and Radical Scavenging Activities of Some Ruta L. Extracts

Cennet YAMAN [1] , Deniz ULUKUŞ [2] , Osman TUGAY [3]


Ruta L. geleneksel tıbbi bitki olarak yaygın kullanılan, Rutaceae familyasının cinslerinden biridir. Bu çalışmada, yabani Ruta chalepensis L. (toprak üstü kısmı) ve Ruta montana L. (yaprak-çiçek ve gövde kısımları) türlerinin metanol ve etanol ekstraktlarının antioksidan aktiviteleri incelenmiştir.  En yüksek ekstraktsiyon verimini R. montana  (çiçek-yaprak) metanol ekstraktı sağlamıştır (% 15.11, 151.12 ± 0.78 mg / g). En düşük verim ise R. montana (gövde) etanol ekstraktında (% 2.67, 26.66 ± 0.50 mg / g) tespit edilmiştir. R. chalepensis metanol ve etanol ekstraktlarının kuru madde içerisindeki toplam flavonoid madde içeriğinin, R. montana  metanol çiçek-yaprak ekstraktı hariç diğer ekstraktlarından daha yüksek olduğu gözlenmiştir. Toplam flavonoid ve fenolik madde içeriği en az R. montana gövde kısmının etanol ekstraktlarından elde edilmiştir. Ayrıca ekstraktların 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) ve 2, 2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS) gibi radikal süpürücü aktiviteleri araştırılmış ve çözücü bazında değerlendirildiğinde R. chalepensis  ekstraktlarının daha yüksek aktivite sergilediği gözlenmiştir. Sonuç olarak, bu çalışmada elde edilen verilerden yararlanılarak Ruta ekstraktlarının doğal bir antioksidan kaynağı olabilirliliği tartışılmıştır.

is a genus of the Rutaceae family, mostly used as a traditional medicinal plant. In this study, the antioxidant activities of methanolic and ethanolic extracts of wild Ruta chalepensis L. (above ground plant) and Ruta montana L. (leaves-flowers, stems) were assessed. The results showed that methanol extract of flower-leave of Ruta montana provided the highest yield of extraction (15.11%, 151.12±0.78 mg/g) whereas the lowest yield was obtained in ethanol extract of stems of Ruta montana (2.67%, 26.66±0.50 mg/g). Total flavonoid content in dry weight of methanol and ethanol extracts of Ruta chalepensis was found higher than other extracts except methanol leaves-flowers extract of Ruta montana. It was determinated that ethanol extracts of Ruta montana stem sustained less total flavonoid and phenolic content. Also, radical scavenging activities such as 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and 2, 2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS) of extracts was investigated, and according to the solvent, it was revealed that extracts of Ruta chalepensis exhibited high activity. As a result, it has been discussed that Ruta can be used as a natural antioxidant by taking advantage of these data. Ruta L.

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Primary Language tr
Subjects Science
Journal Section RESEARCH ARTICLE
Authors

Orcid: 0000-0002-2364-8171
Author: Cennet YAMAN (Primary Author)
Institution: BOZOK ÜNİVERSİTESİ, ZİRAAT FAKÜLTESİ, TARLA BİTKİLERİ BÖLÜMÜ, YOZGAT
Country: Turkey


Orcid: 0000-0002-9627-5492
Author: Deniz ULUKUŞ
Institution: SELÇUK ÜNİVERSİTESİ, FEN FAKÜLTESİ, BİYOTEKNOLOJİ BÖLÜMÜ
Country: Turkey


Orcid: 0000-0003-3980-7648
Author: Osman TUGAY
Institution: SELÇUK ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ
Country: Turkey


Dates

Application Date : November 21, 2018
Acceptance Date : January 2, 2019
Publication Date : April 30, 2019

APA Yaman, C , Ulukuş, D , Tugay, O . (2019). Bazı Ruta L. Ekstraktlarının Biyoaktif Madde İçerikleri ve Radikal Kovucu Aktiviteleri . Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi , 22 (2) , 193-201 . DOI: 10.18016/ksutarimdoga.vi.486352