Yabani Yenilebilir Bir Mantar Olan Lycoperdon molle Pers.'nin Antioksidan ve Antigenotoksik Potansiyeli

Buğrahan Emsen; Büşranur Güven; Abdullah Kaya

doi:10.18016/ksutarimdoga.v22i45606.523756

EN TR

Yabani Yenilebilir Bir Mantar Olan Lycoperdon molle Pers.'nin Antioksidan ve Antigenotoksik Potansiyeli

Öz

Mevcut çalışmada, yenilebilir önemli mantar türlerinden biri olan Pers.'nin kültüre edilmiş insan periferal lenfositleri üzerindeki antioksidan ve antigenotoksik etkilerinin incelenmesi amaçlamıştır. Kurutulmuş taze L. molle'den elde edilen metanol (LMME) ve su (LMSE) ekstraktlarının farklı konsantrasyonları (1-100 mg/L) ile muamele edilen hücrelerdeki toplam oksidan durum (TOD) ve toplam antioksidan kapasite (TAK) değişimleri test edilmiştir. Bu analizlerin sonucunda, LMME ve LMSE'nin 100 mg/L'lik konsantrasyonun hücrelerdeki TOD oranını negatif kontrole kıyasla 0.05 düzeyinde yükselttiği belirlenmiştir. Her iki ekstraktın 1-25 mg/L konsantrasyonlu uygulamalarının sebep olduğu TAK düzeylerinin negatif kontrol grubu tarafından ortaya çıkarılan TAK oranından yüksek oldukları tespit edilmiştir. İlgili ekstraktların hücreler üzerinde genetik hasar oluşturma düzeyleri mikronükleus (MN) ve kromozom aberasyonu (KA) testleri ile belirlenmiştir. Her iki ekstrakt grubunda da 50 ve 100 mg/L konsantrasyonlu uygulamalar haricindeki denemelerin sebep oldukları MN ve KA frekanslarının negatif kontrole kıyasla istatistiksel açıdan (p > 0.05) farklı olmadığı tespit edilmiştir.

Anahtar Kelimeler

Genotoksisite,Makromantar,Oksidatif stres,Sitotoksisite

Destekleyen Kurum

Karamanoğlu Mehmetbey Üniversitesi Bilimsel Araştırma Projeleri (BAP) Birimi

Proje Numarası

13-YL-17

Teşekkür

Bu çalışma Karamanoğlu Mehmetbey Üniversitesi Bilimsel Araştırma Projeleri (BAP) Birimi tarafından 13-YL-17 numaralı proje ile desteklenmiştir. Desteklerinden dolayı Karamanoğlu Mehmetbey Üniversitesi BAP Birimi'ne teşekkür ederiz.

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Buğrahan Emsen ^*
0000-0002-9636-2596
Türkiye

Büşranur Güven
0000-0003-2858-491X
Türkiye

Abdullah Kaya
0000-0002-4654-1406
Türkiye

Yayımlanma Tarihi

31 Ekim 2019

Gönderilme Tarihi

7 Şubat 2019

Kabul Tarihi

18 Nisan 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 22 Sayı: 5

DOI

https://doi.org/10.18016/ksutarimdoga.v22i45606.523756

IZ

https://izlik.org/JA65GF59TL

Kaynak Göster

RIS / Bibtex

APA

Emsen, B., Güven, B., & Kaya, A. (2019). Yabani Yenilebilir Bir Mantar Olan Lycoperdon molle Pers.’nin Antioksidan ve Antigenotoksik Potansiyeli. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 22(5), 724-732. https://doi.org/10.18016/ksutarimdoga.v22i45606.523756