Lemon Peel Extract for Synthesizing Non-Toxic Silver Nanoparticles through One-Step Microwave-Accelerated Scheme

Israt Jahan; İbrahim Işıldak

doi:10.18016/ksutarimdoga.vi.737063

TR EN

Mikrodalga Hızlandırmalı Yöntemi İle Limon Kabuk Ekstraktsiyonu Kullanarak Non-toksik Gümüş Nanopartiküllerin Sentezlenmesi

Öz

Bu çalışmada, mikrodalga hızlandırmalı ısıtma sistemi yöntemi ile limon kabuk (Citrus limon) ekstraktsiyonu kullanarak biyofonksiyonel küre şeklinde veya oval şekilli gümüş nanopartiküller elde edilmiştir. Çalışmada gümüş nanopartiküllerin oluşumunu tanımak için UV–vis absorpsiyon spektroskopi, FTIR ve XRD analizleri uygulanırken, nanopartiküllerin morfolojik özelliklerini ortaya çıkarmak için TEM ve Zeta analizi uygulanılmıştır. Üretilmiş AgNP’lerin UV-vis spektrumu, 445 nm’de karakteristik maksimum absorbansını göstermiştir. Fitosentezlenmiş gümüş nanopartiküller, Z-ortalama değeri 41,86 nm olan poli-dispersiyon haline getirilmesi ile birlikte herhangi bir agregasyon ve agglomerasyon olmadan birkaç ay boyunca mükemmel stabilite sergilemiştir. Daha sonra, sağlıklı fare fibroblast hücreleri (L929 hücre çizgisi) üzerindeki biyosentezlenmiş bu Ag NP’lerin non-toksik özelliği doğrulanmıştır. Bu durum, tıp bilimlerin yanı sıra çeşitli biyolojik uygulamalarda da bu nanopartiküllerin potansiyellerini göstermektedir.

Anahtar Kelimeler

Lemon Peel Extract for Synthesizing Non-Toxic Silver Nanoparticles through One-Step Microwave-Accelerated Scheme

Abstract

In this study, biofunctionalized globular or oval shaped silver nanoparticles were obtained by using aqueous extract of lemon peel (Citrus limon) via microwave-accelerated heating system. While UV−visible spectroscopy, FTIR and XRD analyses were applied to recognize the formation of nano-silver, TEM and Zeta analysis were employed to reveal their morphological features. UV–vis spectrum of fabricated AgNPs indicated its characteristic maximum absorbance at 445 nm. Phytosynthesized silver nanoparticles were poly-dispersed with Z-average value of 41.86 nm, and showed excellent stability for several months with no aggregation and agglomeration. The non-toxic nature of the developed Ag nanoparticles was further confirmed by applying on healthy mouse fibroblast L929 cell line, which may expand their potentials for further studies related to medical science and other biological applications.

Keywords

Teşekkür

This study was produced as part of the PhD dissertation of the first author. The authors would like to express their cordial gratefulness to all the lab members of the Polymeric Biomaterials and Macromolecular Synthesis laboratory at Yıldız Technical University for their precious support and assistance. The authors also present special gratefulness to Dr. Fatih Erci and Dr. Rabia ÇAKIR KOÇ for their immense support.

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Israt Jahan ^*
0000-0003-4166-1617
Türkiye

İbrahim Işıldak
0000-0001-9654-1386
Türkiye

Yayımlanma Tarihi

28 Şubat 2021

Gönderilme Tarihi

13 Mayıs 2020

Kabul Tarihi

3 Temmuz 2020

Yayımlandığı Sayı

Yıl 2021 Cilt: 24 Sayı: 1

DOI

https://doi.org/10.18016/ksutarimdoga.vi.737063

IZ

https://izlik.org/JA47YK97XZ

Kaynak Göster

RIS / Bibtex

APA

Jahan, I., & Işıldak, İ. (2021). Lemon Peel Extract for Synthesizing Non-Toxic Silver Nanoparticles through One-Step Microwave-Accelerated Scheme. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 24(1), 1-10. https://doi.org/10.18016/ksutarimdoga.vi.737063