Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

Burcin Yalcin; Merve Güneş; Ayşen Yağmur Kurşun; Ghada Tagorti; Ezgi Golal; Bülent Kaya

doi:10.18016/ksutarimdoga.vi.1224968

TR EN

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Öz

Birçok insektisit formülasyonunda kullanılan sentetik bir piretroid olan tetramethrin kalıntılarının çevre sağlığı ve canlı organizmalar üzerindeki olumsuz etkileri endişe konusudur. Bu çalışmanın amacı, tetrametrin'in hedef dışı bir organizma olan Drosophila melanogaster üzerindeki genotoksik ve gelişimsel etkilerini değerlendirmektir. Bu nedenle Drosophila hemositlerinde komet testi kullanılarak DNA hasarı üzerindeki etkisi, Drosophila kanat SMART kullanılarak da mutasjenik ve rekombinojenik etkileri değerlendirilmiştir. Ayrıca tetramethrin'in Drosophila gelişimi üzerindeki etkileri larva ağırlığı, larva uzunluğu ve yumurta verimi ölçülerek değerlendirilmiştir. Sonuçlar, tetrametrin'in sadece yüksek konsantrasyonda larva ağırlığında ve uzunluğunda bir azalmaya neden olduğunu göstermiştir. Ayrıca yumurta veriminde konsantrasyona bağlı bir şekilde azalma gözlenmiştir. Komet testi sonuçlarına göre, % DNA'da anlamlı bir artış olmadığı için DNA hasarı indüklenmemiştir. Ancak tetrametrin, SMART testinde mitotik rekombinasyonu indükleyerek genotoksisiteye neden olmuştur.

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Yapısal Biyoloji

Bölüm

Araştırma Makalesi

Yazarlar

Burcin Yalcin
0000-0002-9694-5839
Türkiye

Merve Güneş
0000-0003-3278-0542
Türkiye

Ayşen Yağmur Kurşun
0000-0003-1657-6808
Türkiye

Ghada Tagorti
0000-0003-4597-8320
Türkiye

Ezgi Golal
0000-0002-7685-7479
Türkiye

Bülent Kaya ^*
0000-0002-0491-9781
Türkiye

Erken Görünüm Tarihi

21 Ocak 2024

Yayımlanma Tarihi

1 Nisan 2024

Gönderilme Tarihi

3 Ocak 2023

Kabul Tarihi

7 Eylül 2023

Yayımlandığı Sayı

Yıl 1970 Cilt: 27 Sayı: 2

DOI

https://doi.org/10.18016/ksutarimdoga.vi.1224968

IZ

https://izlik.org/JA36BP97LH

Kaynak Göster

RIS / Bibtex

APA

Yalcin, B., Güneş, M., Kurşun, A. Y., Tagorti, G., Golal, E., & Kaya, B. (2024). Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 27(2), 304-315. https://doi.org/10.18016/ksutarimdoga.vi.1224968

Cited By

Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi

https://doi.org/10.18016/ksutarimdoga.vi.1574067

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Tetramethrin'in Drosophila melanogaster’ de Genotoksik ve Gelişim Üzerine Etkilerinin Araştırılması

Öz

Anahtar Kelimeler